Document jN4VomGXNQkG75ajj5VMDQrp

St. Paul, MN 5544-1000 651 733 i ! 10 May 23, 2003 fc 2 Z < o - S T By Hand Delivery Document Processing Center (7407) Office of Pollution, Prevention and Toxics U.S. Environmental Protection Agency 1200 Pennsylvania Avenue, N. W. Washington, DC 20460 Attention: Section 8(e) Coordinator P e: Dear Sir/Madam: TSCA Section 8(e) Submissions T _ A c r 3^! ^ ompany repuests tha* EPA place the attached studies in the I bUA Section 8(e) docket. We have included an index for these studies identifying the study title, test substance and CAS number. A CBI version of this index and the studies also is being submitted today pursuant to EPA procedures. 3M has concluded that data in these studies may not be, strictly speaking, corroborative of previously reported or published information as defined in EPA's ' reporting guidance or otherwise potentially may warrant 8(e) submission based on EPA's reporting guidance. 3M appreciates EF A s attention to this matter. Please contact the undersigned if you have any questions or require further information reqardinq this submission. ' .a Very truly yours, L i . n a m c i m c t . r\tStiU, m .U Executive Director 3M Environmental Technology And Safety Services (651) 778-4331 kereed@mmm.com CONTAINS NO CONFIDENTIAL BUSINESS INFORMATION SUBMISSION BY 3M COMPANY ON MAY 23, 2003 H N N M ttN M U i Exploratory 28-Day Oral Toxicity Study with T7250, T-7251, T-7252, T-7253, T-7254, and T7255 by Daily Gavage In the Rat Followed by a 14/28-Day Recovery Period (NOTOX Project 264656) m IW llilli l i l l i i i i i i l Separate studies for each chemical: CBI removed); Hexanesullonamide, 1,1,2,2,3,3,4,4,5,5,6,6,6- Tridecafluoro-n-(2-Hydroxyethyl)-N-Methyl -100% ; i-Butanesulfonamide, 1,1,2,2,3,3,4,4,4-Nonefluoro* N-n(2-Hydroxyethyl)-N-Meihyl -1 00% ! i|g |f f p |g CB! removed); 68555 75-9; 34454-97-2 aS3-~ ;s3fs Exploratory 28-Day Oral Toxicity Study with T7125, T-7126, T-7127, T-712S, and T-7129 by Daily Gsvege in the Rat Followed by a 14/28-Duy Recovery Period (NOTOX Project 256679) Cyclohexanesulfonic acid, decafluoro(pentafluorme!hyi)-, polassium salt (CAS No. 57584-42-3) - 66-70%; Cyclohexanesulfonic acid, decafluoro(trifuloromethyl)-, potassium salt (CAS No. 68156-07-0)-18-22%; Cyclohexanesulfonic acid, nonaf)uorobis(triftuoromethyl)-, potassium salt (CAS No. 68T56-01-4) - 9-13%; Cyclohexanesulfonic acid, undecafluoro-, potassium salt (CAS No. 3107-18-4}1*3% 67584-42-3; 68156-07-0; 68166-01-4; 3107-16-4 0S 03-- 1X 3$* Subchronic 90-Day Oral Toxicity with T-6524 by Daily Gavage in the Rat Followed by a 26-Day Recovery' Perioc 65% Sulfonamides, C4-8-alkane, perfluoro, N-(3- 179005-06-2 (dimelhyloxidoamino)propyt), pofassium CAST 179005-06-2; 20% Amine oxide C8F17S02NH(->0)CH2CH2CH2N(CH3)2; 15% C3- C7 K-saits of amine oxides CNF2N+1S02N-)(+K)(- ?0)CH2CH2CH2N(CH3)2 A Study fur Effects on Embryofoelal Development [CBI removfed] of the Rat (Inhalation Administration) [CBI removed] Evaluation of the Ability of T-5870 to Induce Chromosome Aberrations In Cultured Peripheral Human Lymphocytes (with Independent Repeat) 2-ethoxy ethyl acrylate 106-74-1 oo3~ S3<fS osrt>3(S 3 S tm Chromosomal Aberration Test of T-6695 Using CBI removed] Cultured Mammalian Cells '' CBI removed] m ir Acute Orai Toxicity Study in Rats (Exp. No. 920584) (Test Article: Intermedlo 1249) Acute Oral Toxicity Study in Rats (Exp. No. 930321) (Test Article: 501149) Sxin Corrosivity Study of T-5799 In Rabbits (DOT/'JN regulations) Skin Corrosivity Study of T-5800 in Rabbits (DOT/UN Regulations) 2-methyl-2-butanone-(4-sulfonamidophenyi)hydra2one; Molecular Formula: C11H17N302S 3H-pyrazol-3-0ne, 2-(4*aminophenyl), 4-dihydro-5(1-pyrrolidinyl) 1-Oolanesulfonyl Fluoride - 87.5%, Other Alkyl Suitonyl Fluorides and Acidic Impunits -11% , Water - 5.4%, Octanesulfonyl Chloride -1.4% %Octanesulfonyl Fluoride- 87.5%, Other Alkyl Sulfonyl Fluorides and Acidic Impurities -11% , Water - 5.4%, Octanesulfonyl Chloride -1.4% . Unknown 30707-77*6 40530-63-5; Unknown; 7732-18-5; 7795-95-1 40630-63-5; Unknown: 7732-18-5; 7795-95-1 n it* o $ c 3 -\ iH fS 5o 3- /S 3 6 f oSoS*/S 3 * f Primary Dermal Irritation/Corroslon Study of T5635 in Rabbits. (OECD Guidelines) Primary Dermal Irritation/Corrosion Study of T5897 in Rabbi's (OECD Guidelines) Okin Corrosivity Study of T-7030.1 in Rabbits ( witn Protocol TP4205 attached) CBI removed] [CBI removed) Isophthaloylbls (2-methylarziridine) - 97%, Toluene - 7652-64-4; 108-88-3; 2%, Xylene-0.5% . . 1330-20-7 [CBI removed] . [CBI removed] Dermal Sensitization Study of T-5474 in Guinea Pigs - Maximization Test (EPA Guidelines) Water (CAS No. 7732-18-5) - 68.4% ; Dodecylbenzenesulfonic Acid (CAS No. 27176-87-0) -17.5%; Polymethacrylate (CAS No. 25087-26-7) 11.76%; Sodium Hydroxide (CAS No. 1310-73-2) 2.3%; Unknown - 0.040% 7732-18-5; .27176-87-0; 25087-26-7; 1310-73-2 o5b3-~ /S 3 9 -1 o S ^T L /S3T?~ o&o3-~ /S 3J3 0S03 ~ is rrr DC159626 5.2 Page 1 o f2 53 CONTAINS NO CONFIDENTIAL BUSINESS INFORMATION SUBMISSION BY 3M COMPANY ON MAY 23, 2003 Dermal Sensitization Study of T-5894 in Guinea Pigs Maximization Test (EC Guidelines) (with Protocol TP6164E attached) [CBI removed] [CBI removed] m os<& Dermal Sensitization Study of T-6006 in Guinea Pigs - Closed Patch Technique (ERA Guidelines) Dimethyltetradecyfamine Oxide - 55%, 3332.-27-2; 109-28-4; Oleamidopropyldimetbylamine 18%, 1-Methoxy -2- 107-98-2:106-22-9; Propanol - 5%, Cltroneilo! - 5%, Polyethylene Glycol 25322-66-3; 33939-64-9; - < 3%, Alpha - (Carboxymethyl) - Omega - 7128-91-8; 67-63-0; (Dodecyloxyl) Poly (Oxyethylene) Sodium Salt * Unknown; 7732-18*5; 64 -3% , Trialkyl Amine Oxide - 2%, Isopropyl Alcohol - 19-7 2%, Fragrance Sozio SZ 5467 2%, Water -1% , Acetic Acid - 1%, Miscellaneous ingredients at less than 1% cu re3 - Dermal Sensitization Study of T-7280 in Guinea Pigs - Closed Patch Technique (with Protocol TP2008 attached) [CBI removed] [CBIremoved] Acute Oral Toxicity Study of T-6736 in Rats (OECD Guidelines) (with Protocol TP2069 attached) '' 4,6-dibromo-2-isopropyl phenol ' Unknown Acute Toxicity to Daphnia Magna [CBI removed] ' [CBI removed] j Evaluation of the Mutagenic Activity of T-5870 in 2-ethoxy ethyl acrylate ! an In Vitro Mammalian Cell Gene Mutation Test I with L5178Y Mouse Lymphoma Cells (with ! Independent Repeat) ~' _ j Acute Eye Irritation Study in New Zealand White HP=Benzothiazolium (9CI); SB=3-ethyl-2-((3-(3-(3- Rabbits (Exp. No. 620364) (Test Article: 586442* ethyl-2(3H)-benzothiazolylidene)-1-propenyl)-5,5- 50056) dimethyl-2-cyclohexen-1 -ylidene)methyl)-6-methoxy- 5-methyl-; NM=lodide; Molecular Formula: C32H37N20S2.I 106-74-1 87699-86-3 Acute Eye Irritation Study in New Zealand While Rabbits (Exp, No. 940151) (Test Article: 580066) Thiazolium, 3-ethy)-2-[3-(3-ethyl-2- thiezo!idinylidene)-1-propeny!]-4,5-dlhydro-,iodide; Molecular Formula: C13H21N2S2.I 3065-71*2 is 393" e>JTc>3~ /S 3?foS~o3~~ fS 37# o S o 3-~ 1S 33-? 5o3~~ /S 3 0S03* - Acute Eye irritation Study in New Zealand White 3-ethoxy-carbonyl-methyl-4-eloxy-methylldene- Rabbits (Exp. No. S30529) (Test Article: 1268) rhocianlne; Molecular Formula: C1DH13N04S2 Acute Eye irritation Study in New Zealand White C6H10CIN3O2S Rabbits (Exp. No. 920582) (Test Article: 1248) Unknown . Unknown One Generation Reproduction Study of PFOS - Perfluorooctane Sulfonic Acid Potassium Sail Mevalonic Acid/Choiesterol Challenge.and NOEL investigation in Rats ' ' 2795-39-3 Augmented acute (4-hour) inhalation toxicity study with T-6905 in rats 2% solids of fluorochemical fatty acid ester in water 306974-63-0 oSoS-- /S 3 $ Z - /oSS3 3# T3 " 0$B3 - /S3?Joyo3 - /S 3 (f - DCV596265.2 Page 2 o f 2