Document jBJaYOoZM5Kx2Go4VONGkmMLQ

LIVER ANGIOSARCOMA CASES GCNFiretmL KFX/ASL - ASL AEDKESS dRCDLATICN OF REGISTER ADAMS Dr A Ross Air Products, Allentown, Pa, USA BAGS1AW Dr I MM Norsk Hydro, Newttn Aycllffe, IX BAND Dr P R Oanf-or Control Agency of British Galunhia, Vancouver, Canada EAENES Jnr W C Monsanto, St Louis, Missouri, USA BARR Dr J T BAERAT Dr G Air Products, Allentown, Pa, USA AECRP, Comnencry, France BAXTER Dr Peter EMAS, London, UK SEAUPRE M Government of Quebec Cancer Registry, Canada EENEGI Dr M Naphtachimie, Lavera, Prance BENNETT Dr B ICI HLHhouse, IX EEREA2ZI Dr P Inst of Occupational Health, Milan University, Italy BESC3E Dr Dynamit Nobel, Trolsdorf, Germany BISHOP Dr C EMAS, Bootle, IX B0RREU1 F E Georgia Gulf, Delaware City, USA BCSERR W Formosa Plastics, Delaware City, USA BURGESS Mr David ICI Americas, Wilmington, Delaware USA BIREN Dr David Kemanord, Stockholm, Sweden CARTER Dr JT EMAS, London, IK CHI.A Mr C Enichem Polimerl, Mian, Italy CHANCE Mr M ICI Runcorn, UK CLADS Mr P G AM, Brussels, Selgium (LAYTON Mr H Norsk Hydro, Newton Aycllffe, IX (XNEASSOT Dr J C Chloe ChiMe, Saint-Forts, France DAVIES Mr J G ICI, Everberg, Belgian (2) EE SLOWER Dr Salvay & Cle, Brussels, Belgian DE VOS Mr A J ICL Everberg, Belgian utttz Dr H W B F Goodrich, Akron, Ohio, USA DOLL Sir Richard Imperial Cancer Research Fund, Oxford University, IX DCKBRDWSCL S L Dow Chemical, Midland, Michigan, USA EGPCNT Mr G AEME, Brussels, Belgium QtUNGER Mr H VKE, Frankfurt, Germany ERNST Dr W Berufsgenossenschaft der ChenrLschen Industries, Numherg, Germany FALX, Dr H Chronic Diseases Div, US Dept of Health & Hunan Services, Atlanta, USA FERGUSON Dr D M ICI Anericas, Wilmington, Delaware, USA FOHMANDr D Imperial Cancer Research Fund, Oxford University, IK ERASE R W DiverslTech General, Akrtn, Ohio, USA FRIEDEL Dr H P Berufsgenossenschaft der Cbanischen Industries, Heidelberg, Germany GOLURG Prof L Duke Univ Medical Center, Durham, North Carolina, USA G0S2T0NYI Jnr Dr R E Tenneoo Chad.cals, Fiscatawy, New Jersey, USA gottesmanrt The Vinyl Institute, New York, USA HARRIS Dr WD Uniroyal Inc, Mlddlebury, Connecticut, USA HILL Dr G 3 Alberta Cancer Board, Edmonton, Canada HniMANDrD W Diamond Shamrock Corp, Dallas, Texas, USA HOTERERDr RK BF Goodrich, Cleveland, Chin, USA HXGSCN Mr J EMAS, Bootle, IX HDGG Dr W A Imperial Oil Ltd, Sarnia, Ontario, Canada HOWARD Dr J X University of Otago School of Medicine, Wellington, few Zealand BUMPER? Dr N F Id Australia, Melbourne, Australia JAUVEEX Mr J Chloe CMirrte, Paris, France JERVIS Mr HR Id Minhank, Loodon UR KAERH Dr Bruce Dupont, Wilmington, Delaware USA ---- -------------------------- KREUGER Dr R A BF Goodrich, Akron, Ohio, USA LALOINE Dr J P Salvay, Brussels, Belgian LANHAM Dr John Dow Chsnical Europe, Horgen, Switzerland LAWRENCE Mr J SPI, New York, USA LAHRENCE-JONES Sir Christopher, Chief Medical Officer, Id, Loodon IX LEE Dr F I Victoria Hospital, Blackpool, Lanos, IX LELBACH Prof MC University of Earn, West Germany LEVEQUE Dr G CDF Chtaie, AZF, BuUy-les-Mines, France LEVISCN Dr D A St Jarpjwlcraew's Hospital, Loodon, UK LEWIS Dr P Chemical Industries Association, London, UK lOUVIERMr Solvay, Brussels, Belgian LUSSAIO Dr J Atochem, Francs 00 So CO 2- - WPX/ASL - ASL AECEESS.2 R&S 039932 MAHLARD Dr J M Madlzinsche Abteilung, Luzern, Switzerland MALBJIRA Anna Statistics Canada, Ottawa MAL2DNI Prof C Institute di Oncolcgia, Bologna, Italy MAIIRE Prof Lo Medll-Ade-S, Milan, Italy MAHTUSSI Dr R Montedisai, Milan, Italy MUDIZICN D Norsk Hydro, Newton Aycliffe, IK M3EKA Mr Neste Oy, Espoo, Finland MWIESANO Dr R IARC, Lyons, France MJITI Dr A A Dupexlal SAIC, Buenos Aires, Argentina MINN Dr A Mootante, Brussels, Belgim MJNOZ K3UICN Dr M Rio Rodaitt, Madrid, Spain MacSVEEN Prof RNM Western Infirmary, Glasgow, Scotland NAKAMJRA. S Japanese JVC Association, Tokyo O'SULLIVAN Dr JJ ICI Runcorn, IK OLSON H G VC Safety Association, Louisiana, USA CKEN Dr R Trades Union Congress, London, tX PAUSE Dr G M ICI Central Medical Group, Alderley Park, IK PAOIAU2CA Dr S tfantedlson, Milan, Italy POPPER Dr Hans Mount Sinai 'Medical Center, New York, USA POSSBERG Dr J Whcfcei-Chende, Munich, Germany HJECH Dr A M Atochem, Brignoud, France HJRDHAM Dr J ranadian Centre for Occupational Health & Safety, Hamilton, Canada RAMBAED Dr J RP Rseherches, Antony, France RAN3NES P Norsk Hydro, Porsgrunn, Norway RICHARD Dr P Rhone Poulenc, Roussillon, France ROBSON Mrs D Saskatchewan Cancer Foundation, Regina, Canada RCDRIGUES Dr MJF ICI, Sao Paulo, Brazil ROUSH Dr G Monsanto, St Louis, Missouri, USA RUTY Dr J Atochan, St Auban, France SAIG Dr J NIOSH, Cincinnati, USA SARAOd Dr R IARC, Lyons, France SCHEFFERS Dr M L DSM/CTMD, Geleen, Holland SGHEPER Dr H University of Manitoba, Winnipeg, Canada SERDItxE Dr D Diamond Shamrock, Dallas, USA SHAH Dr Has CMA, Washington DC, USA SIGRIST Dr J Shell QriMe, Berre L'Etang, France SMITH Dr E Division of Ehvironnental Health, World Health Organisation, Geneva, Switzerland SMEK Dr P M Llandough Hospital, Penarth, UK SPIRTAS Dr R Nd/NIH, Bethesda, Marylarri, USA STAFFORD Dr J Somerset, UK SIARECKER Mr BASF, Iuduigshafen, Germany TAMBURRO Prof (H University of Louisville, USA TER. HAAR Dr Gary Ethyl Corporation, Baton Rouge, Louisiana, USA TEHWIESCH Dr B Qiendsche Werke Euls, Kreis Recklinghausen, Germany THEBTAnr.T Dr Gilles ItGill University, Montreal, Canada TfflESS Prof Dr AM BASF, Ludwigshhafen, Germany JHUS-EVEtCCN Dr E Norsk Hydro, Porsgrum, Norway THXTSON Dr D H Career Treatment & Research Foundation, Halifax, Nova Scotia, Canada TCRDOIR Dr W Shell, An Den Haag, Holland VAN MR bHH Dr H J AECI, Sasolburg, South Africa WA1LACE J R Esso, Sarnia, Ontario, Canada WAL.TEMAIE H BF Goodrich, Cleveland, Ohio, Usa WEJDUNG S 0 Kemanord, Stockholm, Sweden WHEELER Dr D J ICI HUlhouse, UK WREEIZR R N Union Carbide, South Charleston, USA WHISTDN Dr J ICC HUlhouse, UK WHITE K H Duperial, Buenos Aires, Argentina WILDSKI 0 ELectrocbendcal Industries, Acre, Israel WTL1IAJ5 Dr EMJ BP Chemicals, Penarth, UK WILSON Prof R Harvard University, Cambridge, Massachusetts, USA ^ WRIGHT Dr A P ICI Wilton, UK YORK J ICI Everberg, Belgiun From: Dr B Bennett, Medical Department, Imperial Chsnical Industries Pic HUlhouse Site, PO Box 4, Ihomton-Cleveleys, Blackpool FY5 4QD, UK. February 1986 CONFIDENTIAL REGISTER OF CASES OF ANGIOSARCOMA OF THE LIVER DUE TO EXPOSURE TO VINYL CHLORIDE - REVIEW DATE 1 JANUARY 1986 PREFACE: Acknowledgments, significant changes and comments 1. The new cases in the Register are the following : France Germany UK 18 23, 24, 25, 26, 27 11, 12 2. There are amendments from the previous Register against the following cases: Germany 21, 22 US 36, 38 3. I would like to thank Dr De Sloover, Dr D M J Williams and Dr Friedel for informing me of new cases. 4. For the case corrections I would like to thank Dr Friedel, Mr J T Barr and Mr R W Frase. 5. For other corrections and information, thanks to Dr D Forman, Mr J T Barr, Mr T H Sutherland and Hr N F Humphry. 6. I should be very grateful if all recipients of the Register could continue to keep me fully informed of any new cases, or, if they should hear of other Companies who have dcquired a case of ASL, it would be much appreciated if I could be notified by the appropriate person. It is extremely helpful if new information is supplied in tabulated form, using the headings in the Register as far as possible. 7. I would like to thank the many people who have suggested research topics, and should be grateful if I could be kept up to date. 8. I shall be happy to supply to any recipient of the Register a copy of the Paper "Exposure to Vinyl Chloride and Angiosarcoma of the Liver: a report of the Register of cases'* by Dr David Forman, myself, Dr John Stafford and Sir Richard Doll, published in the British Journal of Industrial Medicine, November 1985 (42: 750-753) Dr Brian Bennett Medical Department Imperial Chemical Industries pic Hillhouse Site P O Box 4 Thornton-Cleveleye Blackpool FY5 4QD England February 1986 660 S'Sb 1706600 S'SH IMPERIAL CHEMICAL INDUSTRIES PLC WPX/ASL 2 - LANGIOCASES,4 Index LIVER ANGIOSARCOMA CASES (REVIEW DATE - 1 JANUARY 1986) Table Sequence Belgium 4 Canada Czechoslovakia France Germany Italy Japan Norway Sweden UK USA Yugoslavia Incidence of Cases per annua (Table 1) Distribution of Cases by Country (Table 2) Page 1 2-3 A 5-8 9-14 15 16 17 18 19-21 22-28 29 30 31 ASL Case Numbers by year of Death (Table 6) ASL Case Numbers by year of first exposure (Table 7) Western Europe PVC Producers - Start-up Dates vs ASL Cases (Table 8) USA PVC Producers - Start-up Dates vs ASL Cases (Table 9) Canadian PVC Producers - Start-up Dates vs ASL Cases (Table 10) East European PVC Producers - Start-up Dates vs ASL Cases (Table 11) Japanese PVC Producers - Start-up Dates vs ASL Cases (Table 12) South & Central American PVC Producers - Start-Up Dates (Table 13) Australasian PVC Producers - Start-up Dates (Table 14) Page 42 43 44 4 5+46 47 48 49 50 51 Pattern of Cases by Factory (Table 3) Latency Periods (Table 4A) Distribution of Latency Periods (Table 4B-4H) 32 33 34-40 Annual Geographical Incidence (Table 5) 41 ir.i* t i | HUC1UH IHi'tKUL ClItHtCAt. INMiSTKleS H.C MVtill An. Jo. .re, C.i.i - B.t. i l January HU) W/iSl._l - LAKU I0CA&2 3,4 l 2 1 4 54 1 a 10 11 U n 14 15 14 COUNTRY AMD lertvtNcx KO NAME Oft INITIAL* DATE Of KITH CUHTAN* FACTORY riftST vc EiroSUftIC DATE Of DIAGNOSIS AGE AT DIAGNOSIS years or nrosuftfc to DUCHOftlft TEARS or axroauftft DATE Or DEATH HUTOtOClCAl. C0HTUNAT10M ESTIMATED mosuRi I.IVEL OCCUrATJON OTHER CAREER HIGHLIGHTS OTHER COHHfcHTl rei.ciijh 01 12.01.11 lolvay j i | 01 1 1 SR 2* Ot 40 Solway i. 00,02.5H 00.OS.24 41 i> w 2t.04,24 Tee Ulfth Autnelaenar Driller la a Hepatic taete 14 yra foundry la Oct 11)4 im-lHft expoeeJ to Toly worker (1 r.) were awraal. Retired 200 |i|w 5 yra (11 yra) rb 1125 for 1 lira Uerk la ftteee lloapltal lead far day lad. 4 cIhwI* Hey It24 cal induatry certainly Cuwplaia under Cllaical ead 100 career Jatella io 4 to t*1 are ftlvan la a paper by iiiUclm* *mrmr JluUlet at el In Arch, ftalft. axpoead to 50-200 pp Hud. Sue. llfft. Hcd. ft bra per Tree. Hvi. day U 25a1 Lei* It2) yaftaa loclavae 401-412 ilfi-iNC eapoaed to 50-200 ppa la auto clave mua T57TTB~ pin 1525- 50 n RETIRED i r#b itn 10 01 42 00.10.19 It w * 23 10 ft) Yaa Oft.42-01. 4) 01.42 -10.21 200 pjaa fth/day 04.41-12, 44 * 200 rv* Aotoelaeear rtrvnan alnca 5 yra 5 alba 10 n. Operator 1 yra Rathe. 1 at alia July 29a Thoracic pain 02. It. Hepatic teat* altered 10.?t. ReaUiwa cctioftrapliy tl.lt. Hep*** iccioay 02.SO. Clivaot herapy. lufotaallua jtlveu In lattar 12 Noe 1RM I run Dr Oa ft louver. SS66&0 SSfcf S1^ g660 r(* 2 CANADA Slmt I IMPERIAL CHKHICAL 1NWMTIIES PLC LIVER An|loearcoea Caeaa - (Review Datet I Jan 1984) m All detea uhi UK eyalee DA - MONTH - TEAK UPX/ASL_1 - LAH(U0CAflKB,7 t 2 7 4 5* 7 * t 10 11 11 11 14 15 14 COUNTRY AND REFERENCE HQ KAHE 01 DATE OP INITIALS IIRTN COHPAXI FACTORY rim vc EXPOSURE OATS OP DIAGNOSIS ACE AT DIAGNOSIS TEAM OP EXPOSURE TO DIAGNOSIS TEAM OP EXPOSURE DATE OP DEATU HISTOLOGICAL CONI'IRKAT ION ESTIHATEO EIPOSUII LEVEL OCCUPATION OTHER CAREER UICHLJGJIia 0T1IES COHKENT* CANADA 01 02 0) 04 OS 04 or 0B Of SIUUII 1CAN 15.12.11 DU 1155 41 11 11 02.09.55 Tee 06.01.14 DO mi 41 u u 21.12.52 Vei 24.0*.If DU 1142 42 11 10 21.01.42 Vm 05.04.If 1145 1167 4* 32 12 21.01.68 Taa OI.OJ.tl IS.12.If Of.11.11 11.05.20 11.01.21 1144 196* ST 14 05 05.07.4* Yea DO DTI 51 34 11 10.04.71 Ye* 1144 1972 51 24 25 24.11.72 Ye* 1141 111) 51 12 05 12.06.71 Yaa 1946 1974 51 II 24 04.09.74 Ye# Reactor cleaner Operator Booker pelyeerlaatlen HataUuiwi! Operator al]lwr||6t, pipefitter UtirUed overtlea Seoker Operator, foreman Worked uviirt lea Hon* a* ok a r Ractor cUlMf Operator, foreman, water cooIIar unit Worked overtine Smoker laactor cleaner Malar cooling unit Worked overt lea Seoker Raactor cleaner Maintenance, millwright UorUd overt lee Seoker * Raactor claanar Machine eltop operator and poly noli Uorkad overtlee Seoker Raactor claanar Ha Inteuauce machine atop la plaut 25 prat Seoker Furnace op. pipefitter maintenance Worked overt lee Seoker Pi)ii by Ur P DELORME In Anomie* d'Anatoala p*lhoU|l4)u farU, 117* Vo I 7) No 2 pplOS-114 chlaa tMi ai Ned UOi a liepatoea end SSL eleuiltaneeueJy N|i 3 CANADA Bltccl 1 1MPEHIAL CIIEHICAL iNttimiEB tUl DAT - Hflfrm - UAI *nTit*i uu UK LIVE* Caaaa - (tavtaw Data] I Jan 1384) . 2 3 4 3& 7 1 * 10 11 12 13 wvn/asl t - LAiwiocAaea.l it 13 P li CuUNTNT AND AElfcHENCE NO BAHI 01 INITIAL! DAT Of mm an in nt FACTUAY msT vc EXPOSURE DATE or DlACttOUII ACE AT DIAGNOSIS TEAK! Of ixrosoNt TO DIAGNOSIS TEAK! OP tiroSUAE DATE Or DEATH HIJTOUM3ICAL CONTINUATION ESTIHATED EXPOSURE LEVEL OCCUPATION OTItU CANSEH 111 CULI CUTS OTIItN COMMENTS CANADA 10 lt.0J.ll 1433 tm it 13 it oo.o4.ir Tl Htcur clur Ttiruaca op* a^lnlanauca, packaging Ea-anafcar ZE660O S$H 866600 SSU 4 CZCCIKISUlViUClA UfPEEUL CHEMICAL IHDUSTEUS PLC LIVES An|loircM Cum - (livlw P4tll I Jao WJ W1/JJI.J - IAHCIOCA3ES,* I 2 i 4 14 7 1 10 it 11 1) 14 IS 14 COUNT BY AWO EEf EJtEHCE HO DANE OS INITIALS OATS or IUTII COMPANY fACTOir mat vc EIP03UEE OATS or OtACHOSIB ACE AT DIAGNOSIS team or CXP05UKC TO DIAGNOSIS mis or CXPOSUME DATs or DEATH UlSTOLOUICAL COHriiHATlOH EST1HATED smsittc LEVEL OCCUPATION OTUEE CANEEI UlCirUCIlTS OTUEE COHHEHTE cirrous wVAKIA 01 1ft.04.14 t.t* Co Novaky 01.07.SJ 14.11.11 41 14 14 14.tl.ll Tu Aotoclavo Cloanor IAKC Jatiar of 1--4--62 Salat la Iron Prof A David of Cant ra tud U^IUm au4 01 at.07.if lilt* Co Nov*Ay 0i.ll.10 11.11. H ii u n It.M.M Ym Autoelava Claaaar IAKC lattar of l-A-ftl |iv aonaofiat altaroA dal** for iLlo cai. I Lava acccptad Ik* cLan|ea aloea tlM data* coaa fro* Prof A Davlf of tb* Contra of Induatrlal ll||Uao and Occupatloual data* cooa orlfiiially Iron HI02HI. pl i FRANCE S1i I I lHVERIAL CHEMICAL INDUSTRIES L'LC LIVER Ang L os* rcom Caaua - (XavJau Datat I Jan S6) Wi/ASIJ - LANGlOCASKS.Iti 1 t 1 4 i6 7 1 > 10 11 11 11 14 11 16 COUNT XT AND REVERENCE NO NANS OR INITIALS PATE Of RUTH COHfANf FACTORY heat vc EIFOSUEE DATE Of DIAGNOSIS ACE AT DIAGNOSIS YEAH OF rJtroauAE to DIAGNOSIS YEARS OF EIF03URE DATE OF OEATN UiSTOlitflCAL COKrtkllATlOH ESTIMATED Eirosust LEVEL OCCUFATIOH OTUEJt CAREER HIGHLIGHTS OTHER COMMENTS FRANCE 01 H 11.04,24 ir louas- 00,01.46 11,01.62 41 11 i* 19.01.67 Vaa III|h AuUclava Hie* woilar aa4 clooasr It yra al Arch. Hal. Frol. 1 10 u 1 Ho* 71 V 171-117 02 3 IK 01.06*11 rcuK IrljMiU 06.01,16 11.01,71 61 it 11 lt.UI.7J Tea Ulali 1 yn on Italian Raf, (N10SII no aonoaar origin C Suimatoa at coanaftt) 10 yri on al Houaoll* (tolyacr praaao laalloo oaJUalo 1 Hit* 1977 t 711 01 NAV 06,01.10 if Si faun 00,00.46 11.01,71 11 11 04 HOE i 1 i 01 1 17.01.11 rcui irl|nowl 19.10.41 lt.01.7i * 11.01,IS rcuE irfgnouj 11,01,61 11.01,76 IS 16 11 l 19 29.06.71 Tea 16 04.01.76 Y*a 11 11.01,76 V III lb fatywarkar 10 yra aa auloclavs cleauar Coapouadlni 1 jrro VCH production Hat. Ratf at 16 yra Italian FOU al Arch. Hal* Frof. 1 17 a' Sktphord* 6 Juna 71 Souyar, Haooa f 111-111 Nlh No iuMr |ir<Htuctloo workar r. rvc Ml I ration II fra NUN folyvorkar 11 yra 1 Itlior acutony Rof F Coiadara 9th Fab 1976 at #1 taaalaa costal las Uoapttau* 10 Saytnkra 2)Si:lal Uraphf 1976 Iouh4 ASI. Fravluusly l)llkaarilta| Nona frua ASI. SHgloaarcono 4)RJgbc Alto Hspalaclooy FI 1 Icluwakl al al La Nuuvolla Fraaaa Hi4Ua)< G66o 0t?660 S'Sd p-(- 4 FRANCE Bhavt 3 1HKHIAL CHEMICAL INDUSTRIES FLC UVCI An|lQircMi Ci - (Kvl Datel I Jan 1966) UM/i5L_l - LANCIOCASES.I I 1 1 3 4 jR 7 R t 10 11 12 11 14 13 14 COUNTRY A NO REFEIEHCE NO MAHE OR INtTlAIJ DATE OF RUTH COMPANY FACTOR! FIRST VC Etrosukt DATE Of DUCNOSli ACE AT DIAGNOSIS YEARS OP flPOSUKl TO DIAGNOSIS VRARR Or DATE Of txrasuR* DEATH HISTOLOGICAL CONFIRMATION tSTTHATRO EXPOSURE LtVEL 0CCUFATIOH OTUER CAREER HIGHLIGHTS OTHER 1 COMMENTS FRANCK 04 r* 14.04.34 fCUK Irl|au4 01,03.31 11.Oi.74 41 i 1* 13 11.09.74 lu Moderate <1930-1*40) (NIOSH 1 y may* flltret too 12.09.74) 10-11 yr* polyworkar u4 work* UVT Title nan kil AOL prior to AS. Ann* da Hal* Puli July '77 P 443 4 4. AOL wee found In 197) live yre before Ail. 0? CJR 3i.OA.27 ir 9t Auban 01.07.30 A! tar 4* 24 22 01.07,74 lit HlRh Fltnt fere- 1*71-4 .4.1. Died f daatk (HIOSK no aA In C(|M 1. epttcaeeli NIOSH c MM at) palytir St Ant.. Sail! liver Italloa lea Ion found 00.07.76 slier eulopey OR A 01,04,34 Rolvay Tovaue 11.0S.S7 01.11.11 42 i* i* 30.01.77 Yea Holmu 4 yrt packer cl nr 14 |ri autoclave Marker Had kaen tunnel worker pravlouely 09 nri OR.10,14 If Si Foua 10.01.41 1A.01.74 43 IS 21 IS.11.77 Ym Vary UIrIi rolyoer* 10 jrra In Operated 4,74 194R-l944 laatloa tulphur kc for ruoovel el Liiur operator, acid factory, liedur Iron Expoture eutecleaeer, atoreVeepar 4 1 tvar end 1164-1*7* utoctave Roaeral died after oeloleneiico eervtcea accond mrRtal optrtt ton for blllo krone lilal f 1 alula Taper by Or Rely et el In Arckivat d Jlaladea Frofuaaioeale Vol AO No 4 1979 paftaa 741-J, 1 r|i ) rUHCI Shaat 3 i l 13 COUrtflT AKD AEKfclENCE HO KAHC OK INITIALS OATH or SIXTH 4 OJHTAMT IHPKHUL CHK HI CAL IHMI^TMJKS TLC t.lVEH Ai|lairc{Mia Caiti - (Mvltu Datal I Jam IfU) WX/ASLJ - LAHUI0CASKS(I2 5i 1 A nt 10 11 12 14 rACTUMT r ust vc MJfUStlKK MATE OK MACHOS [| ACK AT DIAGNOSIS teaks or TOKXFOSUHft 0IACHOSIA TEAKS Or Exrosm DATE Or DEATH HISTOLOGICAL COHPtKHATlOK ESTUUTEU Eirosuxt LEVEL OCCUrATlOH 15 OT1IEK CAXEEK highlights 1* OTLItl ' COHHEHTS France 10 vr ii L 12 ii ii HI 314.01.lt xr It loaa 00.11.54 I0.01.7A 11 21 10.01.71 Iti tr u ii15*01.12 St Fbm 66.0LU ll.oi.7t 44 11.11.74 Tea i4.64.i4 rcut ))lrl|iu>ud 0S.dl.4t od.ol. 41 li.6l.Jl lolvay Tivaui lJ.ol.6J 16.04. 74 ' (6 16 --n-- lJ.04.7t Vu 16 n---- li.04.54' Ya* 01-01-14 Ctiloa st r0 ChUla (ranaerly if) 1*41 4i00.07. --~n-- ----- ii------ ]4 it.07.81 V#> HltL Nlth Au(cUm daaur 10 yre U aacltaalcal aa|lonerIng laAuatry 1*44-1554 1S4I-1S46 jtolfiur laatloa |aral Furpoaa wf4oUrU-ri*n VCH ayiitfcaal a (HC1 A Aeatyt *m) ForuM <*** A* ailtrlaa) IS 7] r.tlr.4 Pled af pulaoHary aabutlM S day* altar aurgary High Ifainoair pro4actUii acufl pljraei-- laatloa operator Autocleanar i tit, Auto~ oparaUr I yr* ejfcla Cl|;atta tcWlc. uuliar until I10 yra ae 1*74. Ill all auaatlUr U at 2*77 im to S rn. eaallary vara Qaaoplitjival Copoljraata Manufacture varlcaa. 4 rfa Ssirjical liUrwnt Ion 25.03. It (rttl.t Iw ialec|4*ay) Vary tilth IS4J-1S7S 1tJi-lSIS ni workISO-H75 All ijrjiaa af aalaiaaaaca Job* o lateraltt~ aaufeclura ently 4 aalnlaaanc a HI5-1 All ! VCH roly froceaa __________ J-t>660 S^a fltl | FRANCE SUtet 4 IMPERIAL CHE HE CAE, INDUSTRIES PLC 2^6600 S'Sd LIVE* AnRloaarcoua Cat** ~ (Ravlau Dalai I Jan USA) \ 3 3 A 34 7 a 1 10 il 13 13 WX/A3LJ - LANCJIOCASEE,! 3 14 13 14 comm and mCKEIICK HO NAME Oft INITIALS OATft or I1RTU COHfAHt FACTO** first vc Ftrosufts DATE OF DIAGNOSIS ACE AT DIAGNOSIS TEAKS Or EXPOSURE TO DIAGNOSIS TEAftl OF urosuse DATE OF OAATJI IIISTOEXICJCAL C0NF1KMATI0K ESTIMATED EXPOSURE LEVEL occurAT ION OTHER CAKEED MICMLlCUtS OTHER COMMENTS Franr* 1 3 \>tr 03.01.33 Cliloa At foai 07.01.33 2B.01.12 43 t; i; Allvt Tat UUL-10 ft Autoclava Otlata Kuila raia c leantr (foiMrlf 7 jrra 1153-1**3 v> luloeUvi op*rator 1*41-1*42 J C Conteaeot Latiar of 3 10 1*43 14 CIM n.or.n Qiloa Si ft 17.10.41 03.01.1) 41 41 31 03.0A.a3 Tat m ik-n 7ol]rtirlaa(<` Oilata Ha4.nl.- lan frocaaa (fo rat dp Lw - 1 |Ia Han ar) Halalanaaca Worker Naaltb 4 Safety Agent Rattled Jan 1*7*. J C ConCeaaet l.al lara of 3 10 1*41 and 13 7 44. u llAft 13.01,13 a to* It Font 17.04.41 03.0A.il AO 14 ia oi.oA.ai Vta II Uh - Autoclave Ollier aectofa Ra 11 rail CbUla 1) yet Claitrr ol St Puaa 01.01.7* (Fomarly 1*44-1*11 Factory 1*71- J C Cantaaaat ar> 1*74 Latiar of 3 10 1*41 ftia 14.01.41 lolvay Tivaui 0V.O1.il 11.03.M 41 31 n 27.l2.flA 13.01,04 tUgb-12 jrra Autoclave Lou - * jrrt Cleaner O*.03.44 Klftlit Hipaitclutf 03.03.4434.09.44 cUaaoiliarapy lor luuft- |iarl lal renlaalou. OS.K - liver iarurranee. 10.44 - liin|i avolwl loa of Ilia dlteaae fill I GERMANY Shot tl IMPERIAL CUEK1CA1. INDUSTRIES PIC L1YKR Aug I oaarcoa* Caaaa - (Ravlew Datoi 1 Jan 1906) WI/AUJ - LAHCIOCASERJA 1 2 ] A SA 7 1 9 10 11 11 11 ii IS U COUNTRY AHD REVERENCE HO HAJ1E Oft INITIALS DATE Of RlRTlI COMPANY PACTuttY rtasT vc EXPOSURE DATA OP DIACH091S age at 01ACH08II YEARS OP EXPOSURE TO DIAGNOSIS YEARS Or EXPOSURE DATE Or DEATH HISTOLOGICAL CUHURKATiOM ESTIMATED EXPOSURE LEVEL OCCUPATION OTHER CAREER UICUL1C1ITR OTHER OQHHEHTR GERMANY 01 01 01 00.00.10 Djrautt TrolaJorf 01.10.14 19.09.tB 10 11 11 11.01.49 7.. (NI0S1I) 00.00.11 Oyn*U TroliJutf li.IO.JJ n.oi.Jo 19 11 11 ia.ii./i 7*. (MIOSH) 00.00.10 Rbalnfal- 09.04.31 oo.oi.n A3 11 it lo.io.n 7*. (MIOSII) Jan l rijrwoiVit fsljfwilar rilling paatlcld* atroca) cau with vc KaporlaJ tinJnr nan poijnwrIsntInn twrlara In N10511 Mat of SI.3.77. TUIa af cumaa la atrlctly corrad How* war 1 wwnJar what liar Ihla nan bad high i[Hiiara to WCH In hi* cau lilting ofratloaf DA 00.00.30 Uackar lurft* u.oi.i; 14. It. 74 AA ii 17 IS.11. 74 Y* (Hioail) 100-300 rfm faljfMrlar 4 IIS! waa Clinical hauao* but M|h Uapotarr uUclaifttr Jalalla In during 1 jft nutln*Mf far 1 yr papr bp awtadtiMr Cofcal at ! Virchow# Arch A Path 1974 171 p US-101 Efr660 S9d t't?660 S^y p*ja 10 GERMANY filita t 1 IMPERIAL CHEMICAL INDUSTRIES tlC LIVLK AnftlotarcDa* Casts - (Ievlev Datei I Jan 1966) UM/ASL_1 - LANG10CA3ES,1 3 1 1 3 4 Si 7 6 1 10 11 11 13 14 IS 16 country and AKmENCE MO HJlMC OR INITIALS DATE Or RUTH CO*IfA NT rACTOR t rusT vc MfOfiUBE date or DlACttOStl ACE AT DIAGNOSIS TEARS OR EIFOSURE TO DIAGNOSIS TEARS Of urosutE OATS or DEATH HISTOLOGICAL COUn ItMAT IUH ESTIMATED EXPOSURE LEVEL OCCUTATIOH OTHER CAREER lit CHI. 1 CUTS OTUEH COMMENTS GERMANY OS (HIOSH |Jvss ss Cass 06) 00.00.St Hosebet frankfurt 01,04.60 io.11.71 ia 13 OS U.ll. 74 Taa (NIOSII) SO Cheats aaya *cLenletry laboratarlan In tlia Techaalofilcal Baaaarcli Dapartnaat * (NIOSII a aya assistant factary chanlat which aay be wranfi tranaletlea) Co nf IrtteJ R|iorts4 uaJar oon-potynerlaalloA workers la NIOSII llat of 31.3.77 eE 1 * 76. 1 funU think title la a corraat alaaal(leal Ion by NIOBII. The nan nay Leva keen InvalraS In VCM yolynerlestIon 1* pi lot tl am ar Ja oaln plant. 06 (NIOSII |Imi as Cast OS) 00.00. SI La res UelAsIwt 14.11.61 00.00.73 43 i) 11 OR.01.73 Taa rVC - Hsnwfsetura Shift Uafir 01 00.00.16 Necksr srt' 13.04,34 ll.ll.7i 4) n 11 13.11.73 Isa hauean (NIOSII says 11) fVC Menu- all work Incl auto* cleaning >3 yra (1134-64) roranan Tacb Oav 6 yra (1367-1173} 06 00.00.17 Oynaalt TroleJorf 11.07.34 06.04.73 SI 10 10 13.11.73 Taa 1 Tolyworker t r*t* i GERMANY Sheet 1 IMPERIAL CHEMICAL INDUSTRIES fLC LIVER Ai>| (> rcoM Caraa - (Ravtaur Patti ) Jan 1944) Uri/*3L_2 - LANOIOCASES.IS 1 *1 COUHTMT ANU lEPEKENCE HO 1 NAME OR INITIALS 1 OATS OP R1RTU 4 COMPANY 14 7 A 1 10 II 11 11 14 FACTORY FIRST VC EXPOSURE BATE OP DIAGNOSIS ACE AT DIAGNOSIS TEARS OP EXPOSURE TO DIAGNOSIS TEARS OP EXPOSURE pate or PEATU HISTOLOGICAL CON MRUAT IQ* ESTIMATED EXPOSURE LEVEL OCCUPATION 11 OTHER CAREER UlCItLICUTS 14 OTHER COMMENTS GERMANY OR oo.oo.it CUIt Karl 10.01. 41 14.04.74 41 11 11 14.01.74 fti LUr* paake 11 fra pulp* wrlar JmI 17l auta- alava claaalai Coat rel roo* * IT* 10/74 Co nl 1 rued Aaari|i a{ii>aiira Ural ri 110 ri. ftCC 1000 pp. Heat 1 fra a*. 71 ppa. La at* ft av 11 ppa 10 CHIOS It |ivii at Cii Ik) oo.oo.it am Ha rl oi.oi.4i 00.01.17 <0 it 10 or.01.77 Yea Uti4 paeke 10 fra poly- uorkar lacl 111 auto* elava alaaalAR Average expoaure (Irat t yr* 1 SO nee 1000 p|ua. I.aat fr a* 71 pl*. am latter of H.04./4 H (H10SH ||vm * Case 10) It 00.00.11 Hacker lurRLaura* 10.10.14 14.04,11 41' * 11 00.00.11 r >*!( TralHarl 00.00.41 00.|0 71 1* 14 11 14.04.71 Yi 4 07.10.7? laa NIrR 1 1 fra auto clave cleaner 19 pro Miter operator PVC Hamr* faclura Autoclava uorkar lor 4 ,r. i______________ Sfreeeo SSy 9fr66E0 S$H ri n CEKMAHV Sliest 4 1 COUNTRY AND REFERENCE HO 1 i --------5-------- NAME OX INITIALS DATE OS mm 1 COMPANY mrCHUL CHEMICAL INDPSTKlU ELC LIVES Aitglujarcoee Cem " (Rivlaw Hitil 1 Jen 196b) ------- 5-------- i rACTUM 1 MUST VC exposure ) DATE Or DIAGNOSIS ft ----------- i------------ 10 ACE AT DIAGNOSIS YEARS or exposure to DIAGNOSIS TEAMS Or EXHJSURI 11 DATE OS DEATH ii ILISTOLOCICAL CONFIRMATION W1/A1U - UNtiiaUEUjl ii IST1HATED imsuit LEVEL n---------OCCUPATION n antes CAEEEft KICJIUCUTS ------------n 0TILES CUtftJENTS CERHAUY 11 00,00.14 Lonu WeWakut 00.00.40 OS.04.74 43 1ft u IS.OS.7ft Ye* ---------- n---------- n (MTOSII ilvaa this II C... 11) ;" ! i i i ! i 11 i ao.oo.i9 UatVir Not Aft la Me l*tlr <il II 12 SI*. Hr Tried*! mH this wee * flatteuepl' llnlliirtlAM D.r Spalaerohr* V ( citelnnei of ttl oeaopli*||o*) not attribut able to VCH 4 not rocoRftleed in luduetrtel Alaeae* 19.10.1) "ooor w ii ii n.io.H To* i Autoclave claenar and worker* Drier operator* Later aliUt leader oo.oo.ii Drnialt TrotiJeH "Jo.oi.ii 01.09. J* ii ii 20 01.09.il Yea Nigh Autoclave {LilUdi A5L end worker till luapeeliJ Hepatocellular 1944. A SI. t Carcluon* Leader anJ Nil 1975 eater J* f>* rot */) P M Met latter of 30th June ISftQ eocloelot data iroo Hr H F lrladel of SO Chaola r U Met latter ( 10ih June 1910 aucleatng date (roe II r Erledal ( SO Clienle wlikdrawlni title caea in|li*rcoa cenflierJ 09/71* Sooe detail of title 4 alee caaee 9, U, 15* 14 1 17 |lrn In NAN Report lor 1971 Aii|lu**rco*e* cuuf 1< e*d g full detail* of lllueaa elnca Iferch 1971 |ivee la HAW Had Inap Hep lor 1971. HI 1ferent detail* glvea In VC AaauclateJ Dleueee ip l.albecli end Heretuller <.1901 > i.7t. r*i u 3EKHAKY Shtai 3 iHMtXlAl. CHEMICAL INDUS TRUE TLC LIVER AiiAioeercoae Caaee - (Ravlcu Date* 1 Jea 1966} UYl/ASl._2 - Mt*GI0CASE8,ll 1 2 3 A 34 1 t 9 10 11 u 11 14 13 U COUNTRY AND AEffcHEKCt NO MAUI OR INITIALS DATA OF 1IRTU COHfAHT rAcriHir FIRST VC urosuRK DATE or DIAGNOSIS AGS AT DIAGNOSIS TSARS or BlfOSURS TO TSARS or SiroSURR DATS or DEATH HISTOIXHZICAL CONFIRMATION ESTIMATED tirosuu occurATLUH DIAGNOSIS UVLL OTHER CAREER 111 FLIGHTS OTHER ORWE NTS' GERMANY IT (NIOSU glvae aa Ca a* IS) u it zo 21 21 00.00.3T Dfoul l TreJa4orf ui.n.ti ia.oa.tr U SOOT Hacht CiiJorf TOOT ii.ii.it 505T5T Or.vit Troladorf it.io.it 00.01.11 ii Si ionr Djf.ult Troladorf U.oi.ii oA.6t.to ti oo.oo. ii OynHlt oo.oo.ii Df.Mlt Tralilftrl 0l.0l.tl oo.ot.it pronounced clinical 1 Iver tjratMl) Trl*Jotf ll.io.il 11.01.10 ii si 14 h ii it it it 11 1 6*06. TS Yea 11 iilti'.'Jt" Yea 11 ii.oi.io Via ASL a It.lA.iA Y*a IndallieUoaa of liver wltit Ha teeteeea a lt.0i.80 Taa lUaaanftio EnJoilmi |oe uf llvti utlli it Ot.11.11 Tt* ASL HI|h Autoclave worker MUli Autoclave Worker Autoclave Worker Hl|h Autoclave Worker Mo Aorinearcone coalliaid. Aaauel report of the Norik Rhine Weetphal la Mad leal loepectorate for 1*76 pagee 14T-1II ftlvaa full dalal la VUyl chloride ll aeeaa dlufitaud 02-02. OaeopheReel varlcaa* ladloU|lcl ly cowltrat4 aero oateolrel Dr SeaeliO letter of 11-04-01 to Dr II 0 f AJaua Dr Beache latter uf 13-04-61 to Dr V (1 r AJaoa Ml Ah Autoclave Worker and uorkeA to drying eliup Dr loacke latlar uf 13-04-Al ta Ur W ti T AJaa* ui|h Autoclave Worker Char|ehan4t auWaaquantly forceeu Dr Icacho letter of 11-04-A1 to Or V ti r AJaae ^^eeeo S 8t>66eo SSd 1 r*I* L* GERMANY < Sheet i IMPERIAL CHEMICAL INDUSTRIES PLC LIVER in|lotafctMi Ciiti ( Ii<r Ditai 1 Jan 1966) UPI/ABLI - UHCtOCASES.lt l 13 n COUNTRY AMO RmftEMOE HO HANK OR INITIALS DATE Or IIRTJI GERMANY n ii r 00.00.37 4 COMPANY Vicltr ) fACTORY lf|` luueia 6 rutsT vc tXr05lfRI l*Si 7 DATE or DIAGNOSIS 36.01.7* 6 ACE AT DIAGNOSIS SI ft YEARS Of EXPOSURE TO DIAGNOSIS 14 10 11 YEARS Or EXPOSURE DATE Or DEATH 31 3ft.0*.SI 13 11 14 IS UIRTOLOGICAL courmiATtoN ESTIMATED EXPOSURE UVEL OCCUPATION OTHER CAREER MICULICJITS Ml|h Cbaalatrjr (*100 PPa) Uurkar - 16 OTHER OittHENTS Prof CeJJjkl atatfta ctafttaalaftd. I'rleJel lattar lft.04.SS 34 ML 00.00.31 Uieber ftur|- 1*6* 11.10.61 SA 1) 11 la.ot.n Yt MltL Auloclava Uuua <*100 ph*> Claaaar Pr*f EJar {Munich) letlar 11.OS.SI. Prlcdel Iftltaf 1ft.04.6S IS E.Sclt 00.00. Wicker lurR- ino Raua** 36.0*.6k 56 11 11 14.01.61 Ta wish Pljrelava Uurkar aid Autoclawa Cl aaaar Pruf IiImIi (Munich) frledal latter lft.04.SS it H 00.00.31 CVIll Her) 14.04.14 54 11 ii 13.11.61 Yea uiRh Palirvorkar Di runic llepat it 1* (Ulbechl. frladal 1(tr I9.04.SS 37 UR 00.00.36 DynMlt TroMaM 1*15 16.01.61 IS 11 16 03.01.64 Tea Ulfh Autoclava Clftanar till 1*71 Lalbecli. IrtaJal latter lf.04.SS rt* I 1 ITALY iHPtRIAl CHEMICAL IKDURTAltS ttC LtVIl AA|lourewa Cami - (Ravlaw Dalai I Jan 1914) WX/ASL 1 - LAltCIOCAStR, 1 3 4 14 7 a 9 10 11 U 11 14 11 16 COUNTRY AMD REFERENCE m HAHt OK initials DATA OF KIKTU ITALY 01 (Oe KIQSH aupjtlaftotirjf Hal) 1.0 11.04.14 COMPANY FAH3AC FACTORY Hira Vaatca FIRST VC DATA OF RXP09UKR MACHOS 11 00,00.41 n.ot.n ACt AT MACHOS II 34 TEARS OF EXPOSURE TO MACHOftJl 04 YtARS or RIPOSORt DATE OF DEATH IIISTOIjOUICAL COUF1RHATIOH 01 14.04.71 IVaa ESTIMATED exposure LEVEL OCCUPATION FVC Rat eatroder OTHER CAHECR 111 CtlLI CUTS OTHER COHHEHTS Prlaary luaoor aay kave kaea parlcarJlua. Not lioao- leneoos wtlU other caeaa. a aa 01 St 01 VO n.n.i* Hftitillioi Porto 00,00.17 Mar|hera 11.11.71 14,01,10 Rolvay Ferrara 00.01.11 10.07.71 o 11 04 v% 10.07,17 AMIC Ravenua 00.04.19 00.01.11 11 01 C Daneaia 19,01.17 FAHSAC HI ra 00.00.41 07.01,41 Vaatca 44 11 04 ii.u. n Yaa Fo lyworkar a aa 11 11 10.0).71 Yaa . UlRll Auiocleaner 1971-1 Aid 4 yre (1*11- a variety of 40 Aotoclav i Juta operator Including 11 yra (1*41 - PVC paellnR. id aa n 11 10.01.11 Taa II yre - 1 C - Haver cleaned Vary UIrIi Hutuwif operator auloctavaa. See paper lay aa 1 jrf a - CHIAPPIHO at Hoa-eouker, Madlua 10 yra - al Had Lavoro Coaeuoed Autoclave Vul 4 (1962) little 4 yra - operator 4 }.p 111-161 alcohol. Ho Low otliar Jut lea AOL. la auapcna- loa pat)rair feat Ion. Area Foreman la aaae Dapt lace 1*71. it 1 04.04,41 Tea tUitxm-y Rag eat ruder Htgk 1*47-1971 CoMUtrclel Itapt 1974mi * FapllaLunge talaa of 1 Au| 1941 * Sea lUltont >kid ill Lavora 4S jiUl, 1974* Further Julalla ta letter fro* Dr tfontiaiao of 1ARC oa April tar 1981. 11 Alio aea Kiltoul anl IobJImIU la Acta Oncolo|lca Vol I 1980 pagea >1 - 49, 6^66eo fitt ]fi JAPAK 0S6660 S^tl I HP HUE. CHEMICAL iHMIftTRlftS PLC LIVER An|tircoM Caui " (lvhu DiUl l Jan UPT/ASLJE - LAHCIOCASM,ll 1 2 I A 31 7 * * 10 u 11 1) 14 13 country and tirmHCt no HAM OK initial! DAT! OP IlRTU COMPANY PACTOKY PI Bit VC ' OATS OP tieoauit 8IACHOSJR AM AT DIACNOfil* YEARS OP EXPOSURE TO DIAGNOSIS TEAM OP EXPOSURE DATE OP DEATH HISTOLOGICAL CONPIRHATION KSTIHATEO EXPOSURE LEVEL OCCUPATION OTHER CARPER INCH LI CIIT3 14 OTHER COilHEOTS JAPAN 01 TmJI toil oi.oa.ii Miaul Taataa (no coaMut bf Jap rvc Aaaoc) 0] 30 o2.oa.i 00.04.3) n 14.10.23 a 3) 00.11.31 10.OB. 74 17 a 21 n 11.10.IS u 13 10,08.7i 4 Ta* Via PVC Aaaoc . 13 pm auto aajra not clave known* * Japan cleaner 1944 - Tinea aaal|aa4 to Indicated dlflereni on IS.10.73 work alnca cipoaurea Lad 111 often at Laaltk 3000 ppa up to 1*74 Mot known In polynarlaatlon work ImMIdi autoclave claaitlnR Japan Tlnaa 73.10.73 4 Japanaat PVC Aaaoc lailar of 31.03.10 Japauaaa PVC AaaoclalIon lailar of 31.03.7ft * In Mi latter at lit April l*ftl, Or HoatMia* of 1ARC aayi Ja|)inii KJnlatrj1 at Labour |Ua Data of lla|noali A| of lla|aoila lairi *1 aipoaure 21-04-74 31 21 r<i 17 HORUAY mrttiAL chemical tubumus rLc LIVER AnilomrciiM Cam - (Kavlw Daiat 1 Ju 1966) uri/uu - UHcioaats.li 1 ll COUNTRY AND RETEREHCE HO 1 HAHR 06 INITIALS 1 DATA or RUTH 4 COtLfANY 3 *. 7 * to 11 11 11 14 13 nCTOAT NEST VC PATE or EirosuRt DIAGNOSIS ACE AT DIAGNOSIS YEARS Or EirOSURE TO DIAGNOSIS TEAM Or tirosun DA IT or DEATH HISTOLOGICAL CUKrtSHATIOtl 1 AT MATED iirosm LEVEL OCCUFATIOtf OTHER CAREER HIGHLIGHTS It OTHER CO+fllEKTl NORWAY OL Alt J3.ll,11 Monk fl/J r* 00.03.30 ll.IJ.7l 3* 11 11 04.01 * 71 Via ui|k tor*M*m 1 AutncUvc uptmliar CuaflracA by Dr Tlill*Evinnu cf HU. AC APHE lit s cl 9 June 1971 Hr f llARAI* that All ln4 Anno i intir if A itirt'tip tin* VCH 4 fVC win Mill In iMt liulUlni. Tin VCH un mJ 1 row icatyliu *S66eo ZS660O S'Sd ri l* SWEDEN ikterial chemical industries etc LIVER AjiR loaarcoee Ceeee - (Review Petei I Jea 19 66) wi/*slj - umjiocABts.n 1 31 comm anu REFERENCE NO NAME 01 INITIALS DAT! Of mru 4 COMPANY >4 T 6 J ID 11 11 n u FACT01I mat vc EXPOSURE DATE Or DIAGNOSIS ACE AT DIAGNOSIS YEARS Of IirOSURE TO DIAGNOSIS txAia or EXPOSURE DATE or DEATH UISTOIjOCICAL CONFIRMATION ESTIMATED EXPOSURE LEVEL occurATION 11 OTHER CAREER HIGHLIGHTS 14 ---------------------- j-- OTHER COT HU. NTS SUEPP.H 01 U1 HU IL n.ot.ii 11.11.11 Eeeejutrd Keaenord Suodevali 14.06.11 Sttiulirill 00*01.11 a 30.10.10 * 00.06.71 41 41 i* li 10.10.70 lee falywrlar i) 17 14*06. 71 Tee Ul|b VCN product lee Hr Sjeellu1* latter of 16 HercL 1616 ceufliaa IL wee e feeameer worker wire wee beevltp eapoeed, prebefelp even wore eo tbee e noreel reactor cleaner 01 Ml 10.04.10 KauMrl Sendavail 00.01.47 H.OJ.H 41 1 11 16.01.74 Tat UlRb folywarkir 04 AL 14.11*14 Keeetvor d lualivaU 00.00*46 ii.m.j; ti 11 31 11.01.77 Ya* Nl|b 1644-1616 pelpeer- liatlM worker (11 pro) 4 1616- l*ir for.n 0* .) In flret 11 pre ef ewplopecnl Red keen beevtIp tapneed. 1* 1674, liver bnoreel tip end necruelc ile|flatl. Date conflraaed In Or D Ijrreu letter 16*6.77 o CtflC 01 11.01.1* Kaeanord Sunlival 1 11.01*64 11.11.BO 41 14 14 11.11.BO Tee Hlftb - 1644-1670 6 Yaari Lm - caalrlfu|a paralar 10 leere 1670-1660 4rlor aparatai Letter of laid Nov 1911 true Or David Spree * lu lit* Uttar of at April 1961 Or lUnliMH si UKC y> la CusJan`1 Hjtiou.l bird o( 01 Ht.llti ilv.a 10-01-10 .. d.t. of dt.(n..l. lot C... 01 .nd 13-OJ-7J lot C* 01. fat* 19 JK SU*t l * Jl COUNTRY AND ItrEkCNCE NO 1 MAllI Ot INITIALS 1 DATA Of HATH t COHFAHV UIFASIAL C1LAKICAL INDUSTRIES tLC LIVER Juiito*fcoa Caaaa - (Ravtaw Datai t Jan 1964) wx/aslj - ukciocase924 i 6 7 ft 9 10 11 11 ii u 19 FACTORY FI AIT VC eirosuit DATA OF OlACllOS 19 ACC AT OlACHOSm YEARS OF UrOSURK TO DIAGNOSIS YAAAS Or AlfOSURE OATS OF DEATH IIUTOIOCICAL CONFIRMATION AST MATEO cxrosuiA tlVF.L occurAT [ON OTHER CAIKI UICIILICUTS 16 OfllER COHHENTS UK 01 WJ 10.04.01 IC1 Hilltiauii 04.04.44 01.11.73 71 1< 21 01.17.72 Yaa 100 pr. 1944-1 VCH (For 4 (Fox 6 1941-1 Drlar Coll lar Coll lr 1949-41 papar iaya papar Autfrclava 13.12.71) aajra oparator 13.11.71) 1941-64 Prior Lae aetl Harry Lancal 19-06074 pages 1316-1 OuVtoua 01 fabrication caaa 01 04 JSR 01.04.n ir i 11.04.10 ICI Barry 00.01.46 00.11.74 1? lltUltoua* It.Ot.H 00.04.79 99 09 i.i 14.ll.lt Yaa lUftk Anted ava elaaaar Eipoeura llaltait la 2.44 - 9.41 n II 11.10.79 Yaa HaJlia' 94-1 rra-war llah Mftli ta|tU| packer Flaat 99-4 Drier riant Mvaatiinl dteanance 94-91 rrrrii------------- Anted eve flail packer vorker 99-41 Orlar Flank 41-71 Portnait C 1/1 Naut 96600 SSU tS660 S1^ r*i* 10 UK Shott 1 12 ----------(---------- --i COUNTRY AHO REFERENCE NO UK OS NAME 01 INITIAL* JK DATE Or RlftTIL 10.01.14 COMPANY ir fACTOKY ft* ftf bi GET lill IF Uttj b) ftCl Jt.M.lo ir UTt) 4 rim vc EftrOftUftE OR.01.11 nti nti IMPERIAL CHEMICAL INDUSTRIES PLC UFI/AflL_2 - UNCIOCAflEft.il UVKt iA|UnrcMi Ct - (Itvltu l>aln 1 Jt t9R4) J ---------- i---------- i to il ------------ n------------ --n-- it IS it BATE OF DIAGNOSIS ACE AT DIAGNOSIS YEAR* OF ESPOSURE TO PIACHOS r ft years nr EXPOSURE DATE Or DEATH UISTOLOCICAL COKriSNATIOM ESTIMATED EKPOSUftft LEVEL OCCUPATION OTHER CAREER IMCIM.ICHTS OTHER COMMENTS 00.10.7* 41 31 11 1*.II.7ft 1*11-12 Polyetiuir 1*11-11 L* li ms-to r*ir floor 1*60-44 Poly Cfc*r|lk*u4 1*44-70 Qur|U| Ofiantor iiio-n Prior oporotor oi.ii.to ti/i ii ki ot.ii.w Poly Floor Opototor 1 pro 00*00.00 ib w i.i ll.Ot.M Polr Floor PoiyeliHir 1*63-1 Jlocovory 1*41-1*71 Oft WTH iii.oi.it ir lirrjr it.thi.iO iJ.li.il " 11 it is.ll.il HiOTI SOO .pa !" rp itio-Ji llli-ltu Auloclovt Hultii Hockaoic oparotor 1*40-1*10 1*11-1*17 Qfratr ao Qt*rft*a*4 AcatylaH idUclavi Froftuetlou bullllni rloac 1*17-1*74 Shift |iorvlatir autoclave UlNlnft " Novor tluoal lutodivaa but atiyarvlior1 o Job outolloft otarlMR to lit*pool tlioa .-1- N|i 11 UK KLtf 1 1 OOUHTftY A HD lirtKCHCK HO UK Q 1 HAKE 01 INITIAL* Kicr --s-- om or hath 01.03.1} 4 emirA NT IT imiiAL chemical iHnuaTiiis nc LIVE! Cim " (Nvliti Da tat I Jan 1916) ----- 5----- ~i-- ------ j------- ------ i i 10 it rAcroA* mat vc mom* DATE OF ACE AT DIAGNOSIS DfACMOfltl TEAM* or tirosuak to hiacnusi* mas or cirostnc DATE 01 DEATH Barry 13.01.30 01.01. 31 31 1 14.01.13 WX/A5L_2 - LAHCI0CA1E1, 14 ti --n-- ------ n------- --------n --------n HISTORICAL COWtEHATION Vaa KSTtHATED tirosuii LEVEL OCCUPATION 0Tlt CAKEER it t cim. i cun Hadji* Nlywrlar 1 ynra oo Acryloaltrl la Raala M ant. ilaa prior ta 1930. 4 yaata aAr alntananca. 3 yaara aotor car palntaliop. 1 yaara la Cray Inf Dock. other COUHKHTM 10 CJT 04.0A.AV ir Barry IT.04.4* Ot 03 B4 3T It 4.1 14,03.04 Vaa High - II Eftl|deir Jlaaay goola Infornatfoa aAtbi (300 1944-47. yalilcla di Ivor glvao la ppa). 9f> raya rdrJar uatll final 11 BMillia b*llr 194 V- lltaaa. latlar l1.04. H froo (30 pfo). fed Jut - 41. Blow** dova Or D H J Wllllaaa 11 atonlfca atr1?par (ioo rr-) oparator 1961-70. u clp 01.03.11 ir lirry H.li.lS 01.04.13 u 11 JT 3t.0l.JJ let lit llbouii lt.U3.3V 01.04.13 41 11 14 01.04.13 Tea Utah rolyclaanar 1143 >41 1961-41. fed 49-T9 lirvlca Low VI ~U of* ra tor 41-49. foijr Oparator 49-V9* Loading Hand 19-11. It 11 04.11.13 Taa Lou nu-is Spara aan, Ul(t< It-M bagging low n-ti I leor HIM*. Autoclawa Operator 1939-13 Latter of 04.06.13 Or foul lallla and lattar of 04.04.13 Dr D H Q Kvana Oaaophagaal linaortltiia doa to oeaupliagaal varlcaa dua to Angloaarcoo* of llvar l.rt lar 14.04.13 Dr r 1 l*a SS66E0 S'Stl 9S66C0 S'Sb fa|a 21 USA Sheet I IMPERIAL CHEMICAL INDUSTRIES PLC LIVEI AA|toaarccuu Cueae - (livliu Petal I Jan I9S6) UJt a)iti of 4ati Pit - HONfll - TEAR UPX/ASL_1 - LAHG|OCASC3,27 _ 1 1 6 5 7 a t 10 M 12 11 14 15 16 CUUKTKl A NO REFERENCE NO NAME OR INITIALS cm or 1IRTJI COMPANY PACTUAY FIRST VC exposure DATS or DlACNOSt* ACC AT DIAGNOSIS YEARS OP EXPOSURE TO DIAGNOSIS TEARS OP EXPOSURE DATE OP DEATH UISTOLOCICAL CONFIRMATION EST1HATED exposure LEVEL OCCUPATION omt CAREER NICI1LICUTS OTHER COHHRNTR USA 01 Earl 17.10.11 iro Lou It** Of.11.AS 05.05.75 41 1A 11 05.01. n Yaa Parka villa 01 u.oi.d sro Leula- 15.11.55 00.05.70 IT 14 ii 37.Of.71 Yaa villa (KI03U aajre 11.09.71) 07 EJuard 15.05.15 tra Louie* IS.11.45 11.11.71 56 1ft IS 11.13.71 Yaa OlnwIAJU villa oa tt.0l.14 spa Lou la** 0l.0J.il 11.OB.67 A3 11 15 07.0t.6S Yaa villa 05 15.01.11 iro Uulr lt.06.A4 Ot.OA.6A 51 10 10 Of.OA.64 Yaa villa Pal Cleaner (Slack Jaaa 1974) , 51 Ulaterp Riven Rollins Stana la Annel a NY Art ACAD SCIENCES Ref 1 NT Ac*4 Vol 129 (1979) af Sc Ijrap |>a|a 190 la 1974 Paper Ljr Atao Hack S S Colttna al 1 aaa 1.7.7A OSIIA , ii Pat Cleener (Cf Hack) Pal Claanar (Cf Slack) Loutavllla Courier Journal 03-09*60 Pat Claanar (Cf Slock) Ref 1 Alao Hack JAMA 1.7.7A 9 Hef 1 Alaa Bluck Hef 1 Alaa 11ock Pot Claanar (Cr Hack) Kef 1 Alaa Rtock 06 Rmjr 11.11.11 IKQ Lou la* 11.01.61 00.01.74 A5 11 11 34.07.75 Yaa Auatla villa Jouaal US AU Perea Pat Claanar (Cf Slock) Ral 1 * l.uulavllla tie.a 35.7.75 Retired April 197A Alaa Slack 0} Qurlii 05.05.11 UCC 9 Chirla- 2/.OS.44 00.00,66 AS 1A w 11.01,66 Yaa T Saart too Hal 1 OB 06.05.10 Cootlgrtir NIejara 07.10.46 00,OB. 61 41 n 15 It.06.61 Yaa Ref 1 IMPERIAL CHEMICAL INDUSTRIES PLC USA Sliaat 1 L1VCH AiiilouredM Umi " (Ktvtiu Oat at I J.n 1*44) t 1 I 1 4 34 7 4 * 10 11 UK ayata* of Jalii day Hmrni - WK/ASL 1 - LANCIUCAAeS.il 12 13 14 tl 14 COUNTRY AHO REFERENCE NO HANK 01 initials DATE Op hath COMPANY PACTOAY FIRST VC RIPOSURl DATE OP DIAGNOSIS ACS AT DIACMOAIS TEARS Or Biro&UU TO diagnosis YEARS or EXPOSURE DATE Or DEATH U1STOL0CICAL CONFIRMATION eSTIHATEO EXPOSURE LEVEL OCCUPATION OTHER CAREER HIGHLIGHTS OTHER COMMENTS USA 09 ui.ll.3J IPO Lul " 21.03.43 01,03.24 A3 1* 24 Li.03.73 1** looo pv* Guli* tint* rt Hof 1 liaa wroaiR flfwra ra flr*t apttaura. Loulavilla Tina* 2*.10.74, 11.3.13, 10.1.74 10 14.OS.11 tioodfatr 12.04.31 0U.03.4S 33 If 27 I0.03.il Vm Pol 1 N 2 2*03,09 Coodjiair 14.10.44 00.03.10 41 21 13 14.01.70 iM Hcf 1 12 Pimeti A ll.ll.lt T1 (MlOM faltatauu 11.or.41 02.03.4* 30 10 n 02.03.4* to. Kith 10 yr* 10 yr* ai Utility 4 Sf 1 4 Jaltai Rac1*an r* roactor op. lavvlea op. (not clainar latiar at 14 April 1*71 iraw - taparata Dryar op. huatoll A fail craw claaitad Stripping op. to J T Saawoll 1 pro prior af MCA aarvlca Jo tyro plant 13 Uchi rd 01.12.11 UCC 1 CVarla- n.u.ti 00.03.n a 11 24 07.04. 74 Ti. 1000 ppm Edwa rJ Ian Cl Oitrlaatan Dally Hall 21.7.73 14 Havar JlaR- noaad aa anjliitarcima of llvar. tatorv at too Rlwan la laitar 22 Hay L9S4 friM J A IoIr. 13 Act:oiiotaut j ASL - No a*l* tlaaica af VCH aapoawra. ^S660 S'Sd 8S660O S'Sd fi* 24 USA Slieat 2 IHPERIAL CIlliHlCAt INDUSTRIES Pl.C LIVKK Aiiiluaarcoaa Gaaaa - (Rtvlau PaUi I Jan 1914) UK Ayala* u( dataa DAY - MONTH - YEAR UPl/ASLJt - LANmOCASEA^ll , 2 1 4 14 1 A 9 10 11 12 13 14 11 14 COUNTRY AND EtPEMEHCI MO NAME OR initial* DATE 09 1UTH COHFAHY FACTORY mst VC DATE Of EirOSORE DIAGNOSIS ACE At DIAGNOSIS TEARS or eirosuiR to DIAGNOSIS YEARS Or EirOSUftE DATE or DEATH HISTOLOGICAL CONFIRMATION EATIHATEO ElPOSHES LEVEL OCCUPATION OTtlEA CAREEA NICllLlCltTS OTHER COMMENTS ' USA 14 Jauaa 04.11.2? IFC Howard Loulaviila 04,01,10 00.00,49 41 19 04 37.03.49 Yaa 1911-4 VCH pulyatr* laatlon rtaa 1914 Tabla 4 lu onward a lo UaRunar Amy and otliar Taatlnouy to aurvlca. US Aaaala 44-10 Amy Cwntlraad U M H Jolinaoa lir 07.01.71 Lou la** 111 12 Paaranboo* 04.0J.il 1IG villa 11.04,13 11.10.74 43 19 19 14.10. BO on 11.10.74 but no Fiit-aorlaa 14.10. AO Dr H N Jultuaoa lattar at 24,1,41 can- IUad daatti 4 yaara aflar J liinAkli 14 Uiart la 13.04.2* *ro Avon Laka 11.09.14 00.00.71 44 31 u 01.il.71 Taa n Navy Ar iliur A yra on taUl Tyra At or* plaatlclaar 4 Carboaat ayaral Ion Ikmflravd la M H JuWaou Ur 07.06,71 Alao iolllii Sion* ai|. 11.01.76 19 Vlrjll 00.00.11 ucc 3 Ctiarla9 00.00.41 19.04.71 40 11 11 04.04.74 Yaa 2000 tVm CNrlil Ian itaa Wl UitRlpOIt Sun Catatta 21 Juna 1971 ttiarlaalon Dally Hail 21.7.71 JO 31.04.11 Coodyaar MlaRara 00.00.11 ID.01.74 1A 11 IA 30.01,74 Taa N10SII lattar of 21.10.79 2) CUaatar 03.09.09 OCC 8 COarla- 00.11.44 Early 72 42 10 32 01.01.77 Taa It 1 nil a aloa 3A yra with UCC at SC RaiIraJ 33.1.77 II USA ih8t t IHPEKlAL CHEMICAL IMMJSTftlES NX LIVES Aji|loiarcM Cjim - (ftovtow Dotoi Jon 1966) UK oyotoa of diti DAY - HOHTII - TEA* VPX/ASE.JI - UH<UOCAStStJ0 2 3 6 1i 7 t * 10 It 12 13 14 13 14 COUKTHY AND SNEAENCi NO HAH* OK INITIALS DATS or mTJi COMPANY r accost rust vc MrOSUItE DATS or DIAGNOSIS ACC At DIAGNOSIS VJCAKS or cirosutc to DIAGNOSIS YKAK3 GY SftPUSUKK PATK or DCATU HISTOLOGICAL CONTI SHAT ION ItSTlHAtCD UPOSUIt UVftL OCCUPATION OTIfftft CAftECR uictiLiciira otuei CttlllKNTS USA 12 ii H (id ui.io.n sro Lulr 11.07,*) 00.01.Jt 32 23 IS Ot.U.H Too villa durlta Kdvord Huoro SOOT n.ui.U Croat AnorIcon Qtuleil Conponv UCC rl tcbburs 01.04.St iro Kata. $ Qiorlo4 ton mi ii.tii.il 30 A0 ii ll Ut.0*.)S Yoa it Hi D.ii.JJ Cholontle- (H10SII >y< It) urcMa {ft laoUall 26/2/79) ftono laiar coal 1 mod la 1 laalnikl lot tor of 3 Nov otar 1SS0 ______ _______ i _______ _________ Loulovl11* TUoo 24.1.76 00 td flO woo til* lOili AS vlclfn ot Bo 114 L*m4 of wlltMO 1 h*d died by 24.1.74 1* Mi lottor of 16.09.SI Or K H Juliaoom conflru Ibl# lo lb* coot dncrllod by D***olir Touborro 4 Yon In Tab I960 A* J Ho it loin* Vol 70 ul60 Hadiiai to for 24 *ra ll-ii non- 1917-33 via # H Uhooltr oolvont off and on vlayl roolai lobouror lotlor of 16.1.77 to unit and Sloporoloo Iiovo boon vinyl rootoa Ot|lOOd MO ] Sloflur4 Alveo ilutajli Boo4 XoniooUl unit flrot oo fittor raactnr cloonor lottor of 26/2779 bolpor, llioo 190 bocM ft ftonlnokl Lift utility ** Mil fllior 1944 teiraau ohllt o|JIUy {3 Nov I960) ouftgool# 1 Il41 NIOSll will on 24,06.61 r.lolu on rojloior olncu eo^loynyni woo tMo naaptaao iaulnatad oy bo oooocl- ai*4 ulib ASL. ii luiior of 20/2/79 ouil too* Kontnokt toiler* of lififii 6S66q 0966S0 SSH r|i 2b USA Sheat ) IHfElUL CHEMICAL INDUSTRIES NX LIVER An|taurcou Citu - (bviaw Detet I Jan 1966) UK ayateo of date* DAY - HONTH ** YEAR UfK/ASI. I - UWfiiOCABES.ll L 12 country and REVERENCE NO USA HAKE OR INITIALS DATE Of RIRTU 2b Jviui Rerry 02.02.22 2V J L ii.at.u furrail 2d 29 20 UVN il.in.u 13.10.01 ll.07.ll 21 o6.ii.il 4 ctttriHt ) ncTtut b FIRST VC Kirosutc 2 DATE OF 01 ECHOS1S ACE AT DIAGNOSIS im LouI** 02.10.42 00.00.22 22 villa (up to 2 (death) plan (tor death) ucc i arir- ol.bl.ti 10.11.It ti *too ucc S Chi{!i- od.oa.tt TTHTTi" eton ucc 1 Cbatle- oo.o6.ti 00.0), to li) Teaneco rtaalogto il.6i.tl Qnaictla lO.li.K M )l 66 UCC S Charia- ll.o6.it 6i.ol.ti w tou 9 YEARS Or EirosuRt to DIACHHSIS 10 YEARS OF EirOSURZ M date or DEATH 12 H1STOLOCICAL CUHMRHATIQH 11 ESTIMATED txrosm LEVEL 14 occurATION ' 1) OTHER CAREER HIGHLIGHTS 14 OTHER COHHEHTS 11 (death) It 11.02.2) it 20 ii.ti.it (NIOSU laya 22 and C Dally Hal J 21) H 66 ant: >6 it li Ai.oi.to 11 --n-- Jo.11.to 66 --n-- oi.ot.ti Yea Yai Yaa Ye* Yaa Yea Bipoaad la Varloue Juba aai degree u rvc Eaolnabl latter of to 22 planta frua lit2/29 and claealcala cold too* to fref. Taoburro but aaln paate lattar of aipaaura racavary to 9/1/29 was to VCH, EVC charting probably oparetar to high paata charging. Ill Auguat 196). TaraJaatad apleyoaat Jaa 1966 Nigh Oparator to txpoaura to 1 H Wtaalar 10.10.26 bulb and 1 tr of 4 Jan dloporalon FVC 1929 and Manufacture Cherleeton Dally Hall 20.U.2R and It KaulevU 26/2/29 1 Kaalnakl lattar of 6/4/29 R KaalnaU Latter# of I9tb June I960 A " UnkaowQ Halatananca 1 )th Nov 190) 9 - Htulul Haclianlc 6 yra llaewhere i\ it. dollar liouaa Oparator 9 rra Nigh (Rut Qieolcal Iroa 19S9 ta Hr Decay aot aa high Oparator io 1916 AlIpbatlc letter aa reactor clii rga Chaatcale U.IO.Rt aoJ cleaner raactor operate* and R K Wheeler uould aiparlanca) frota July 1916 let ter of to data 9.11, Si. Uorted aa Fore*an Alaa Hr Decay labourer Aliphatic letter of frua Qiaolcal 07.01,d) re Juaa 19AI to Hay 1.946 OperelIon date ef death. and nay kav cleaueJ raactor* tn that tine t*f 1} USA Slmt 6 IMPERIAL CHEMICAL INlUfftTSIK* LIMITED LIVER Attgloaercooe Caeee - (Review fiatei Jeu 1944) UK ayittM of 4Ua DAY - MONTH - mi WX/ASLJI - tAMOlOCASES.ll l I 1 4 1* 7 a * 10 11 11 11 14 11 14 COUNTRY AMD ItFtAtNCE HQ HAMS OR INITIALS DATE Or . HATH cot l/ANT FACTORY rusi vc IXFOSURS OATS OK imCrtOSIS US 11 C U Cl room 21-02-0* Honeanto 2 prlIi|fU]< u-io-ii Hooo 00-07-79 U3 33 S rerRueoa OS-IO-17 Jnr tra Uulavlll 0-0*-J4 II-0J-S2 US 34 Mr lyrun M-oi-n iro Loulavl11 , mi oi-n-ai US 31 US 14 oj-oi-n ucc ft Ckorl- 11-0 7-41 too 14-07-41 2 7-OA-ll TUa Ctntral AaU el Tiro oat* Ula lutltar Co 11-04-14 11-04-SI ACE AT blACHOfttft 71 34 4ft n 10 YEARS Or exposure to OlACNOStS O TEARS OS EXPOSURE DATE Or death HISTOLOGICAL CONN AH AXIOM ESTIMATED tirtlSURl UYCL OCCUFATIUM OTHER CARETS III CM LIGHTS OTHER guiihehto It 14 1 7-03-00 An autopay The Jaatli 1940-1911 (u rvc vaa dona and certificate Various Juba auloclava iMadlate |m In pa1)er area) Hr Clroua1 aeuuFectura dealt* given waual sumo aa areu^attoa LUSTSEl `Auftloeercone aa ItattU mi-1944 OfariUr ' Verloue Jobe In In and 'cltanlcala around FVC induatry autoclave* 1944-1973 Varloua clerical jobs la fVC polyaerieatl a laclllly/ latlrad 01-01-71, Infernalloo (Ivan In letter of 74 February 19*1 Iron Ur Walter C Samite of Muuaunto Sprliiftflald to fir A Hiinn of Hunaan to Eu rope. It 1* Allva Tea Multiple Joba Inctudln* Poly Operator -4 fa lire leaner. l*rof Tauburro letter of 11 Au| 1901 * fir H N Jobnauu letter of 1* Feb 19*3. 11 10 04.Oft.01 Til foly Operator 4 Autoclave Cleaner ms-6*. 1943 uri ora to becooe a Cleriyaao. Hr H H Joluuun letter of 1 Hue 1961, 1ft Teb 1983 and 9 Aug 1964. 1ft 14 16-07-61 Via Ilf ftb fro* 1944 to mi. MadIum fro* iftii-ma Dr Decay lettar of 3 Sept 19*3. 17 17 Allva taa Moderate 1934-34 labourer 1934-37 prod helper 1937-70 operator 1970-71 electrician 1 973-pmeent operator R W LaunJrle latter of 11 Sept ilftJj spotted at oedteal May 1901. TaelImj coauaoncad Hay 19*1 1.966C0 S'Sd r<l< I* UJi Ihaal 1 296600 StfH lttrMUL ClttMlCJkL IKIHJSTlUt UHlTtU L1VM Ki>|lontcoai C... - ( *.law P.t.l t Jan 1116) UK ayilH f *.c. HAT - HOHT - TUI WM/A3LJI - UOtaiOCtStJ.Jl l 1 1 4 1A 7 4 10 11 12 11 M 11 u COUNTSV AND SE^HENCS MO KAIJE 01 INITIALS OATS or SUTN CttifANT rACTOSV riMST VC CXPOSUKK DATS or DIAGNOSIS ACS AT DIAGNOSIS TEAM or txrosusc to DIAGNOSIS VEAE9 Or exposuse DATS or HEATH HISTOLOGICAL COHrtUUTiOH ESTIMATED exposube LEVEL OCCUPATION OTltE* CASSES uicnijciits OTIItE coriHENra. US 17 Hr J 1* 01 I) F0 Louia- 1*11 04 OS 44 S4 ii 13 04.0a.64 Vae Mllh UurkaJ Paytoa vlUa rt|uli(ly la PVC araa. la tU tarty 4*ya waa a rate tor claaacr mws. 1aloroatIon glvaa | IlltM 04.01.64 1 roUc M H JohUBOU US 16 JUI 11 01 21 Air ProAueta Calvart City 00.02*41 14.01.64 tt 20 20 21.10.03 Ya* Hlfh Mortal ftr 1*41-1*12 traatloa (isa balpar lo aaalor oparater, claJ raactora, alrlpplas an4 racovary rtaa aa wait aa charslua operator* Tbrvabo cylopanl* aaJ laukopaala alaca 1176* Cull ifaataaal lor arlbrltta 1474* UuJar Or* a cara about 4 aunt La Ualora ila* Lit, had paaaad taudard pliyaloal aiM* 1 n*l Loa 1 uoiitha carllar. J Barr laltara ol 22. 10.64 4 21/01/41. Np 19 JUGOSLAV[A IMPERIAL CHEMICAL INDUSTRIES PLC LIVER Aiiulnearcoae Cooea (Ravlew Dotes Jan I9B6> UI**/ASLJt - UWGIOCASEfl(14 1 1 y 4 1A J s t 10 II 11 n 14 11 It COUNTRY A VO EEglEMCK HO KAHE 01 DATE or INITIALS I11TU COKfAVY rACTOlY rmr VC ElfOSURE OATS or 0IACN0SI3 ACE AT DIAGNOSIS TEARS OS uroauai to diagnosis TSAIS or eirosuAt DATS Of DEATH UlSTULOGICAL COOriAHATiOK ESTIMATED ElfOSUK LEVEL occupation OTHER CANCER HIGH L1CJITS OTHER COtlHENfS . YUGOSLAVIA 01 01.04.14 Jufo Split 00,00.S3 OB.04.7) 1* 30 to US.04.71 Yea Vlll BARIC at al papr Env Noelth r*f pct iv Vol 1 7, l-P 109-192 M?t 01 u.n.n Juro 1.1U 00.00.10 11*07*71 41 n IS 11.07.71 Tu* Vial 1 0} ti.n.ii Jup Sflll Ot.Ol.M U.01.76 41 n 12 11.01.71 T a* Vlnll t 04 11*04*30 Jnt Spilt n.ii.ii 01.0S.7S 41 30 IS 01.09.7S T VUil VCH Production VCH rriNucllon *ln LIa lttar of 1 Oct 1910, Or Sjiirtai of NlOSIl changed Ilia ilatat of Como 03 to VCH productIon vaiploroc. Dr Splrioa lao noil Hurl a new Cana 01 alao a VCH product Ion worker Roao taaluiU Latter of 1 91 k Jhai 19fk> and IARC loiter of 1 April 19A1 9660 S'Sd Page 30 fr9660 S'Sd TABl.E 1 (Review Date - 1 Jan 1986) Incidence of ASL Casea Per Annum By date of deatli 1955 6 7 8 9 1960 1 2 3 4 5 6 7 8 9 1970 1 2 3 4 5 6 7 8 9 1980 1 2 3 4 5 H.B. 1 0 ........................................................................ 0 ........................................................................ 0 ........................................................................ 0 ........................................................................ 1 .................................................................................................................. I ........................................................................ 0 ........................................................................ 2 ........................................................................ 0 ........................................................................ 0 ........................................................................ 1 .................................................................. 5 ........................................................................ 3 ........................................................................ 2 ......................................................................... 3 ................................ 5 '. ........................................................................ 8 ........................................................................ 5 ........................................................................ 11 ........................................................................ 11 ........................................................................... 9 ........................................................................ 10 ......................................................................... 5 ........................................................................10 ................................................................. 5 ........................................................................ 2 ........................................................................ 9 .................... 5 ...............................................................................................................j_2 Total 117 I Does not Include Italian 01 but does Include German 03. 2 The 1977 total Includes US case 24 which Is a Cholanglosarcoma. 3 The 1982 total does not Include US 33 and F 15 who are alive. 4 The 1983 total does not Include US 36 who Is alive. WPX/ASL_2 - LANGIOCASES.35 m 31 Distribution of ASL Cases by Country TABLE USA W Cermany France UK. Canada Sweden Yugoslavia Italy Czechoslovakia Japan Belgium Norway 35 ftftft 26 Aft 18 Aft ft 11 10 5 ftftft* 4 ftft ftftft 4 ft 2 2 2 1 (Review Date - 1 Jan 1986) 2 Total 120 * Omit ItOl - atypical case of PVC bag extruder. ** Includes CE03 aerosol can filler. *** Includes case US 24 which was diagnosed as Cbolanglosarcoma &UlS 33, and 36; and F 15 who are alive. **** Includes one monomer worker. **' ***** Includes two monomer workers. l.e Western Europe North America Rest of World 67 45 8 WrX/ASL_2 - LANGIOCASES,36 Total 120 S9660 Paep 3? Pattern of ASL Cases by Factory 996600 S9y TABLE 3 (Review Date - 1 Jan 1986) (a) H Europe Of the 67 cases in W Europe, 57 have occi rred in clusters at 11 factories. Of the 26 German cases, 23 have occurred In clusters at 4 factories. ASL Cases Dynaniit, Trolsdorf, Germany Chloe Chlmie (Formerly RP), St Fona, France BP, Barry, UK Hacker, Burghausen, Germany Kemanord, Sundsvall, Sweden PCUK, Brignoud, France CWH, Marl, Germany ICI, Hlllhouse, UK Solvay, Tavaux, France Lonza, Waldshut, Germany Solvay, Jemeppe, Belgium 11 8 8 7 5 5 3 3 3 2 _2 57 NB: There are 32 pre 1962 PVC plants in VI Europe; 18 of these have had ASL cases (Ref Table 6) (b) N America Of the 45 cases in N America, 38 have occurred at four factories out of a total of 54 factories:- In N America 43 plants have not had ASL cases. ASL Cases BFG, Louisville, US BFG, Shawlnlgan, Canada UCC, S Charleston Goodyear, Niagara 14 10 10 4 38 NB: There are 28 pre 1962 PVC plants in N America; 11 of these have had ASL cases (Ref Tables 9 & (c) Rest of World The 8 ASL cases are believed to be in 1 cluster of 4 and 2 clusters of 2 cases. WPX/ASL 2 - LANG10CASES,37 p 33 LE A A (Review Date - 1 Jan 1986) l.atency Periods (Years from first Exposure to Diagnosis) W Europe N America Rest of World Summary Country Belgium France Germany Italy Norway Sweden UK US Canada Czechoslovakia Japan Yugoslavia W Europe N America Rest of World No of Cases 2 18 26 A 1 5 11 67 35 10 A5 2 2 A 8 67 A5 8 120 Total Years 35 A 59 A95 7A 22 122 25A 1A61 886 20A 1090 30 39 85 15A 1A61 1090 15A 2705 Average 17.5 25.5 * 19.0A * 18.5 22 2A.5 23.09 * 21.80 25.31 * 20.A * 2A.22 15.0 19.5 21.2 19.2 21.80 2A.22 19.2 22.5A * Of the countries with > below world average. caaea> France, UK and USA have an average latency period above world average, Germany and Canada WPX/ASL_2 - LANCIOCASES,38 ^96600 S^a Page 34 896600 S$d DISTRIBUTION OF LATENCY PERIODS TABLE 4B (Review Date - 1 Jan 1986) WPX/ASL 2 - LANCIOCASES,39 R&S 039969 Page 35 (Review date 1 January 1986) TABLE AC LATENCY PERIOD OF ASL CASES TABULATED BY TEAR OF FIRST EXPOSURE * Cholangiosarcoma ** Aerosol can filler *** DS33 and 36; and F15 still alive. WPX/ASL 2 - LANGIOCASES,40 R&S 039970 Page 36 (Review date 1 January 1986) TABLE 4D LATENCY PERIODS OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND GEOGRAPHICAL LOCATION * Cholangiosarcoma ** Aerosol can filler *** US33 and 36; and F15 still alive WPX/ASL 2 - LANGIOCASES,41 TABLE 4E Page 37 (Review dace 1 January 1986) pLAirr START UP DATE LATENCY PERIODS OF ASL CASES IN SPECIFIC PLANTS (10 OR MORE CASES) NO OF CASES AVERAGE LATENCY PERIOD LOUISVILLE USA SHAWINIGAN CANADA S CHARLESTON USA TROISDORF W GERMANY 1940? 1941? 1939? 1954 12,14,15,19 ,19 ,20,24,27,28,28,28,29,29 31 11,12,14,21,22,23,24,24,26,28 24,30,32,32,34,35,37,38,38,39 12,13,16,16,18,19,19,21,23,25,28 14 10 10 11 23.07 20.5 33.9 19.09 20 Go CO ^ 6eo WPX/ASL 2 - LANGI0CASES.42 039972 Page 33 (Review date 1 January 1986) TABLE 4? LATENCY PERIOD OF ASL CASES TABULATED BY YEAR OF FIRST EXPOSURE AND SPECIFIC PLANT (10 OR MORE CASES) WPX/ASL 2 - LANGIOCASES,43 Page 39 (Review date 1 January 1986) TABLE 4G PLANT START-UP DATE LATENCY PERIOD OF ASL CASES NO OF IN SPECIFIC PLANTS(4-9 CASES) CASES AVERAGE PERIOD SUNDSVALL SWEDEN BRIGNOUD FRANCE ST FONS FRANCE BARRY UK BURGHAOSEN W GERMANY NIAGARA USA 1945 1950 1939 1948 1933 1947 16,19,27,29,31 11,16,18,26,30 21,28,29,37,38,27,41,35 9,17,18,28,31,33,18,19 .17,21,22,25,24,13,21 15,17,21,23 5 24.4 years 5 20.2 3 31.88 8 21.62 7 20.43 4 19 SPLIT YUGOSLAVIA 1941 20,20,22,23 4 21.25 e^ e e o WPX/ASL 2 - LANGIOCASES,44 R&s 039974 Page 40 (Review date 1 January 1986) TABLE 4H LATENCY PERIOD OF ASL CASES TABULATED BY YEAR 07 FIRST EXPOSURE AND SPECIFIC PLANT (4-9 CASES) WPX/ASL 2 - LANGIOCASES,45 Page 41 TABLE 5 (Review Date - l Jan 1986) Annual Incidence of ASL Cases (Date of Death) by Geographical Area Western Europe North America Rest of World Annual Total 1955 7 1961 2 4 7 8 9 1970 t 2 3 4 5 6 7 8 9 I960 1 2 1983 1984 1985 TOTAL 1 1 1 l 4 1 3 6 6 6 7 5 6 5 1 6 4 2 | 66* ** 1 1 1 1 1 5 2 1 2 1 4 2 4 3 3 2 4 0 1 3 1 43** l 1 1 1 12 1 5 3 2 3 5 38 -5 1 11 2 11 9 1 10 -5 - 10 -5 2 9 10 51 25 8 117 list* * Includes G03 aerosol can filler but omits It 01 bag extruder ** Does not Include US33, and 36; and F 15. All Btlll alive. Cumulative Total 1 2 3 4 6 .7 12 16 17 20 25 33 38 49 60 69 79 84 94 99 101 110 115 117 Key Events Viola Maiton 1 Coodrich ccutnfit' Pi.am T WPX/ASL_2 - LANCIOCASES,46 s)o ^ ic>iL .-- SZ66S0 S^a H' -p-u td. Page 42 (Review dace 1 January 1986) TABLE 6 ASL CASE NUMBERS 3Y YEAR OF DEATH AND GEOGRAPHICAL LOCATIONS (EXCLUDING ITOl) KEY EVENTS WESTERN EUROPE NORTH AMERICA REST OF WORLD Viola Maltoni Goodrich 1955 6 7 8 9 1960 1 2 3 4 5 6 7 8 9 1970 1 2 3 4 5 6 7 8 9 1980 1 2 3 4 5 Total FI G1 Swl G2 Nl,Sw2,UKl,It2 G3*** G4.G5.UK3 F2,F3,G6,G7,G8,Xt3 Bl,F4,F5,F6,F7,Sw3 F8,F9,G10,Gll,G12,Sw4 F10,F11,G9,G13,G15 G16 ,G17 F12.F13,UK4,UK5,G18 UK6, UK7,G19,Sw5,G20,G21 It4,F14,UK8,G22,G23 G26 UK09,It5,Fl7,B2,G24,G25 UK10, F16, F18, G27 UK11, UK12 66 Cl C2 US8 C3 US5 CzZ C4,C5,US4,US7,US10 US12.US16 US11 C6.US2 C7 C8,US1,US3,US23 C9.US13 US6,US9,US18,US26 U519,US20,US22, C10,US21,US24* US27,US28 Yl,Y2,Czl Japl Jap2,Y3 Y4 US17, US29, US30, US3! US31 US35. US34, US38 US37 43*** 8 ' * Cholangiosarcoma ** Aerosol can filler *** Does not include US33, and 36; and F15. All still alive. R&S 039976 WPX/ASL 2 - LANGIOCASES,47 Page 43 (Reviev date 1 January 1986) TABLE 7 ASL CASE NUMBERS BY YEAR OP FIRST EXPOSURE AMO GEOGRAPHICAL LOCATION (EXCLUDING 1T01) KEY EVENTS WESTERN EUROPE NORTH AMERICA REST OF WORLD Viola Maltoni 1939 40 1 2 3 4 5 6 7 8 9 50 1 2 3 '4 .5 6 7 ' '8 9 60 1 2 3 4 5 6 7 8 9 70 1 2 3 Frll,Frl6 Frl4 UK1 SwZ Frl,Fr3,Sw4 S3 Fr9, Frl7 Frl2,Fr4 Fr7,Nl,UK8,UK9 Swl,UK5 G3** G15,It3 ,G26 G7,G8,UK4,G19 G11,G16,G18, Frl5*** G23.G28 FR10.G1 Fr8,G4,It2,G2,UK12 Fr6,Bl Fr2,It4 G5.G13.G25 G9,G10,G12,G17,G20 ,G22 G6 ,tJK6 ,G21, B2 Frl3, UK7,Frl8 Sw5 Fr5,UKll UK3, UK10 It5 G24 US24* C3,US27 US13, US29 C2.US19 Cl,C5,US5,US7,US28,US35 C4,US3,OS9 C7,C9,US8,US11,US21,US31 C6,US22,US26 US1 US12 US16 Y2, Cz2 US10, 0S32 US4 CIO, US37 Japl.Yl US18,US33*** Y3 US2,US17,US20,US34 US36*** US23 Czl Jap2,Y4 C8 US6 US38 US30 Total 67 45 8 39977 aj ffo a> * Cholangiosarcoma (US24) ** Aerosol can filler (G3) *** US33 and 36; and Fr 15 are still alive. WFX/ASL 2 - LANGIOCASES,48 Page 44 WPX./ASLZ - LANGIOCASES,49 (Review date 9 January 1986) TABLE 8 WESTERN EUROPE PVC PRODUCERS - SEART-OF DATES vs ASL CASES (OtanWS GQ3 & It .01) SIAKT-UP CDCOTEff NAME CDMPANT NAME IDCATION ASL CASE NUMBER TEAR OF TEAR 1st Exposure 1931 West Germany BASF Ludwigshafen 1933 West Germany Wacker Burghausen 04,07,11,15,23,24 25157,54,55,53,55,69.60 1938 Italy Montecatini Acna 1939 France Rhone Poulenc St Foes 03,09,10,11.14. 46,48,56,41,43, 15,16,17 55,41,48 1940 United Kingdom ia Runcorn 1940 United Kingdaa ICI IHillhcuse 01,04,12 44,54,57 1945 Sweden Kemanord Sundsvall( Stodorik) 01,02,03,04,05 51,45,47.46,64 Switzerland Lonza Sins 1946 France Rhone-Poulene RousUlcn 01 46 1947 Italy Montedison Porto Marghera 02 57 1948 United Kingdom BP Oiem Barry 03,05,06,07,08,09 66,51,62,63,50.50 10,11 66,65 West Germany Huls Marl 09,10,26 61,61,53 1949 Belgian Solvay Jemeppe 01,02 58,62 1950 France Puk Brignood 02,04,05,06,12 59.49,65,58,49 France Khcxie-Foulenc St Auban 07 50 Holland Shell Pernis Norway Norsk Heroya 01 150 1951 Italy Montedison Brindisi 1952 Italy Montedison Tend. 1953 Austria Halvic Hallein Franca Solvay Tavaux 08,13,18 57.63,63 Italy Solvay Ferrara 103 53 Stein Rio Rodano Hernani United Kingdom BIP Aycliffe West Germany Hoechst Gendorf 18 55 1954 West Germany Dynamit Troisdorf 01,02,08,12,16, 56,57,54,61,55,61, 17,19,20,21,22,27 54,61,62,61,55 1955 Stain Monsanto Iberia Monzon 1956 Spain Caiqsa Sabinaidgo Hispavic Torrelavega 1958 West Germany Solvay Rheinberg 1960 Italy S C Ravenna Ravenna 04 59 1960 West Germany Lonza Waldshjt 06,13 62,60 1962 Portugal Clres Oporto 1965 France Rhone-Poulenc Montluccn Italy Pozzi Ferrandina West Germany Wacker Cologne 1966 West Germany Hoechst 1967 France AID Chiade KnansackCFrankfurt) 05* Bal an 60 Soain Rio Rodano Miranda de Ebro Greece Esso Papoas Diavata Salonika 1968 Badiphtl Antwerp 1969 United Kingdom Vinatex Staveley Italy Rinrianca Cagliari Sardina 1970 Italy SIR Porto Torres Sar United Kingdom ia Runcorn 1971 Italy S C Ravenna |Ravenna Soain Hispavic (tertorell Sweden Kemanord I Scenungsund United Kingdom BP Chem IBaglan Bay 1972 Finland Pekana 1Svartback Holland DEM iBeek Limburg 1976 1 France Soc Art D'vinvllMazingarbe 1977 I Spain iMonsanto Iberia(Tarragona * Laboratory worker in Research Department PANSAC, Mira Venice, cot Lni-lirW (Xt 05), due not kncwing start up date of the Plant. Q 39978 Page 45 (Review date 1 January 1986) TABIE 9 USA. F7C PRODUCERS - START-UP DATES vs ASL CASES SIARX-UPl (XMPANX NAME LOCATION ASL CASE YEAR OP YEAR 1 1939? *UCC 1940? *BEG S Charleston Louisville NUMBER 1st EXPOSURE 07,13,19,21,24, 44,42,43,46,39, 27,28,29,31,35 41.44,42,46,44 01,02,03,04,05, 48,55,45,52,44, 06,09,16,17,22, 62,45,50,55,47, 26,33,34,37 47.54,55,53 1946? *UCC Texas City (Partially closed 1977) 1947 Goodyear Niagara Falls 08,10,11,20 46^1,46,55 _ 1943 Firestone Pottstcwn 12 49 Uniroyal Painesville (closed 1975) 1950 Monsanto Springfield 32 51 (Closed 1975 1952 Dow BEG Midland (No FVC since c 1975) Avon Lake 118 54 1953 BPG Deer Park (Formerly Diamond) 1954 General Tire Ashtabula 36 56 (Closed 1984) 1956 Air Products Pensacola Atlantic Refining Brooklyn( Closed late 1960s) Borden Leominster (Closed 1984) Conoco Hebronville (Qosed 1975) BPG Great American Niagara Fitchburg 23 58 Plastics (Closed 1983) Hooker Hicksville (Closed 1980-81) Pautosoto Passiac (Qosed 1984) 1957 Atlantic Tubing Cranston (Qosed 1%7) Tenneco Flecdngton NJ 30 59 1958 Keysor Century Saugus, Cal 1960 HFG Watson, Cal Air Products Calvert City 38 63 (closed March 1982 Re-opened Octalser 1983) Borden Illiopalis 1 1962 Tenneco Burlington NJ I 1963 Conoco Aberdeen, Miss | Stauffer Long Beach, Cal (Qosed 1982) 1965 Conoco Ethyl ** Assonet, Mass (Qosed by Olin 1975. see below) Baton Rouge (Qosed 1984) ( 1966 Georgia Gulf Delsaere City (Formerly DiaDond) | General Tire/Pantas Mt Pleasant W Va | (Qosed 1983) 1 BEG Henry, 111 1 | Stauffer Delaware City (Sold to Formosa 1983) 1967 Allied *** Painesville, 0 | (sold to Robiotech) Hooker Burlington NJ 1968 Firestone Perryville (Qosed 1982) 1969 BEG Pedrlckton NJ 1 Goodyear Plaquenrtne Olin ** Assonet, Mass (Qosed 1975) (See above) (Formerly Conoco) 11 1971 1 Coroco OkJahcma Qty | 1 039979 KPX/ASL 2 - LANGIQCASES,50 Continued Page 46 TABLE 9 (Continued) OSA PVC PRODUCERS - START-OP DATES vs ASL CASES START-UP YEAR 1972 1973 COMPANY NAME Nat Starch Borden Robintech *** 1974 1975 1979 1983 Atlantic Tubing/ Tallyrand Shintech Certain-teed Georgia Pacific Tenneco Firestone Formosa LOCATION ASL CASE NUMBER Meredosia, 111 Springfield Painesville, 0 (sold to Georgia Pacific who converted to polystyrene) Cranston RI (Closed 1982) 1 Freeport, Tex 1 Lake Charles 1 Plaouemine, La | Pasadena, Tex Flaauemine Point Comfort, Tex "" YEAR OF 1st EXPOSURE 1 ! 1 1 1 * My databank has no information on OCC before 1946 or BFG before 1950 ** Refers to same plant at Assonet ***Refer to same plant at Painesville. Allied plant never operated again for PVC after it was sold to Robintech. NB Some of the plants in this list were closed down, some have changed ownership over the years, some have changed their product. R&S 039980 WPX/ASL 2 - LANGIOCASES,51 Page 47 (Review date 1 January 1986) TABLE 10 CANADIAN PVC PRODUCERS - START-UP DATES vs ASL CASES START-OP YEAR COMPANY NAME 1943 (1941?) Goodrich LOCATION Shawlnigan ASL CASE NUMBER YEAR OF 1st EXPOSURE 01,02,03,04,05 44,43,41,45,44, 06,07,08,09,10 47,46,61,46,53 1951 Monsanto La Salle (Closed 1! 175) 1957 Goodrich Welland 1966 E 330 Sarnia 1979 Diamond Shamrock Alb Fort Saskatchewan R &s 039987 WPX/ASL 2 - LANGIOCASES,52 Page 48 (Review dace 1 January 1986) TABLE 11 EASTERN BLOC PVC FACTORIES - START-UP DATES va ASL CASES START-UP COUNTRY NAME COMPANY NAME TEAR Pre 1939 East Germany State Company 1941 Russia State Comps 1950 Yugoslavia Jugo Vinil 1951 Czechoslovakia State Comps 1955 1956 Ease Germany Rumania State Comps State Comps' 1957 Poland State Comps Rumania State Comps 1958 1959 1961 1963 1965 1967 1969 . 1970 1972 1975 1976 1977 Rumania State Comps Hungary State Comps Rumania State Comps lYugoslavia Ohis Bulgaria State Comps Poland State Comps Russia State Comps Rumania State Comps Russia State Comps Yugoslavia Vinilplastika Czechoslovakia State Comps Russia State Comps Yugoslavia Hip Rumania State Comps LOCATION Schopau Vladimir et al Split Novaky Bitterfeldt Icechim Osweicim (Dwory) Tirnaveni Turda Risnov Berente Borsod Borzesti SkoDie Varna Tarnow Dierjinsk Rlmnicu Vilcea Volgograd Zadar Neratovlce Kalush Area Pancevo Rimnicu Vilcea ASL CASE NUMBER 01,02,03.04 01,02 | | I j I I I 1 | I I | I | YEAR OF 1st Exposure 53,50,54,48 57,50 R&S 039982 WPX/ASL 2 - LANGIOCASES,53 R&S 039983 NO ;r04 Page 49 (Review date 1' January 1986) TABLE 12 JAPANESE PVC PRODUCERS - START-UP DATES vs ASL CASES START-UP YEAR 1950 1951 1952 1951 1955 1956 1957 1960 19641966 1967 1968 1970 1971 1973 1974 COMPANY NAME Chisso Corp Kanegafucfai Kag Tekkosha Mitsui Toatsu Mitsubishi Mon Sumitomo Kag Denki Kagaku Nippon Zeon Toa Gosel Ryo-Nichi Nippon Zeon Nlsshin Kagaku Kureha Kasei Shlnetsu Kag Denki Kagaku Kanegafuchi Kag Chisso Corp Tokuyama Seksui San Arrow Kagak Sumitomo Kag Ryo-Nichi Shlnetsu Kag Chisso Corp Denki Kagaku Kanegafuchi Kag Kawasaki Yuki Mitsui Toatsu Nissan Kagaku Shlnetsu Kag Tekkosha Asahi Glass Toyo Soda 1975 1977 Central Kagaku Toyo Soda Unknown LOCATION Minamata Osaka Sakata Nagoya Yokkaichl Kikumoto Shlbukawa Kambara Tckushima Uozu Takoaka Takeo Nishikl Naoetsu Ohmi Takasago Chiba Tokuyama Tokuyama Chiba Mizushima Tokuyama Mizushima Goi (Chiba) Kashima Kawasaki Sakai Chiba Kashima Yokkaichl 1 Hayatsuki Sakata Yokkaishi Kawasaki Yokkaichl Kashima ASL CASE NUMBER YEAR OF 1st EXPOSURE 53, 58 WPX/ASL 2 - LANGIOCASES,54 Page 50 (Review dace 1 January 1986) TABLE 13 SOUTH AND CENTRAL AMERICAN PVC PRODUCERS START-UP COMPANY NAME TEAR 1953 Monsanto Mexica 1954 Policyd 1955 1956 Geon Do Brazil Slchlor 1960 Eleccrochlor Viplastic 1961 InduDa 1965 (SOC Paramanga (1967 start up PET Columbiana 1966 Carburo De Col 1967 Plasticos Omega 1968 Primex 1970 Policasa Petro Dow 1971 Polimeros Mex 1975 Rico Chemicals 1976 ' Petroplas 1977 Indust Resistoc 1978 Huls Brasil Polychem Policyd 1979 PET Camacari LOCATION Lecheria (Mexico) Mexico City (Mexico) Sao Paulo (Brazil) Sao Caetano (Brazil) Capitan Bermudez(Argentina) Mendoz (Argentina) Cinco Saltos (Argentina) Paramonga (Peru) ) Cartagena (Colombia) Medellin (Colombia) Mexico Puebla (Mexico) Managua (Nicaragua) Conception (Chile) St Martin Puebla (Mexico) Guyanilla (Puerto Rico) EL Tablazo (Venezuela) Tlazcala (Mexico) Cubato (Brazil) El Salvador Coatzacoalcos (Mexico) Camacari Bahia (Brazil) ASL CASE NUMBER YEAR OF 1st EXPOSURE R&S 039984 VPX/ASL_2 - LANGIOCASES,55 R&S 039985 Page 51 (Review date 1 January 1986) TABLE 14 AUSTRALASIAN ?VC PRODUCERS START-UP TEAR COMPANY NAME Mid 1950s ICl Australia 1960s B F Goodrich Late 1970s ICl Australia LOCATION Botany, Sydney Melbourne Laverton Melbourne ASL CASE NUMBER TEAR OF 1st EXPOSURE WPX/ASL 2 - LANGIOCASES,56