Document evErdNaQR0gRNED8NqJk30xgq

Adopted at the Twenty-Third Annual Meeting of the American Conference of Governmental Industrial Hygienist*. Detroit. April 9-12, 1961 Threshold limits should be used as guides In the control of health hazards and should not be regarded as fine lines between safe and dangerous concentrations. They represent conditions under which It Is be lieved that nearly all workers may be repeatedly exposed, day after day. without adverse effect. The values listed refer to time-weighted average concentrations for a normal workday. The amount by which these figures may be exceeded for short periods without injury to health depends upon a number of factors such as the nature of the contaminant, whether very high concentrations even for short periods produce acute poisoning, whether the effects are cumulative, the frequency with which high concentrations occur, and the duration of such periods. All must be taken into consideration in arriving at a decision as to whether a hazardous situation exists. Special consideration should be given to the application of these values in assessing the health hazards which may be associated with exposure to combinations of two or more substances. Threshold limits are based on the best available information from industrial experience, from experi mental studies, and, when possible, from a combination of the two. These values are based on various criteria of toxic effects or on marked discomfort; thus, they should not be used as a common denominator of toxicity, nor should they be considered as the sole criterion in proving or disproving diagnosis of sus pected occupational disease. These limits are intended for use in the field of industrial hygiene and should be employed by persons trained in this field. They are not intended for use, or for modification for use, in the evaluation or control of community air pollution or air pollution nuisances. These values are reviewed annually by the Committee on Threshold Limits for changes, revisions, or additions as further information becomes available. The Committee welcomes the suggestion of sub stances to be added to the list and also comments, references, or reports of experience with these materials. Recommended Values Cases and Vapors Substance PPM Approx. Mg. per Cu.M. Substance PPM Approx. per Cu.1 Acetaldehyde ZOO Acetic acid 10 Acetic anhydride 5 Acetone 1000 Acetylene tetrabromide 1 Acrolein 0.5 Acrylonitrile skin 20 Allyl alcohol skin 2 Ally! chloride 5 Allyl propyl disulfide 2 Ammonia 100 Amyl acetate . 200 Amyl alcohol (lsoamyl alcohol)! 00 Aniline skin 5 Arsine 0.05 Benzene (benzol) 25 Bensyl chloride 1 Boron trifluoride 1 Bromine 0.1 Butadiene (1,3-butadiene) 1000 2-Butanone (methyl ethyl ketone) 200 360 25 20 2400 14 1.2 45 5 15 12 70 1050 360 19 0.2 BO 5 3 0.7 2200 * 590 Butyl acetate (n-butyl acetate) 200 950 Butyl alcubol (n-butanol) 100 300 tart. Butyl alcohol 100 300 Butylamine 5 15 Butyl cellosolve (2-butoxyethanol) 50 240 p-tert. Butyltoluene Carbon dioxide 10 . &0 5000 9000 Carbon disulfide - skin 20 60 Carbon monoxide 100 110 Carbon tetrachloride - skin 25 160 Cellosolve (Z-ethoxyethanol) 200 740 Cellosolve acetate (2-ethoxyethyl acetate) 100 540 Chlorine 13 Chlorine dioxide 0.1 0.3 Chlorine trifluoride 0.1 0.4 Chlorobensene (monochlorobenzene) 75 350 Chloroform (trichloromethane) 50 - 240 1 -Chloro-1 -nitropropane 20 100 1. Reprinted with permission from the American Conference of Governmental Industrial Hygienists. Note: The word "skin" following a compound's name indicates that the liquid compound can penetrate the skin to cause systemic effects. t. C** and Vpon (cant. 1 t Subatance PPM Approx. Mg. par Cu.M. Subatanca PPM Appro*. Mg per Cu.M. Chloropicrin 0.1 Chloroprene (2-chloro-l, 3-butadiene) 25 Creaol (all leomera) - akla Cyelohauaa Cyclobexanol 5 400 . 50 Cyclohexanone Cyclobexene * 50 400 Oaeaboru* - akin 0. 05 DUcatona alcohol (4-hydroxy- 4-methyl-2-pantanone) 50 Diboraae 0.1 o-Dichlorobenaene 50 p-Dichlorobenmene Dichlorodifluoromethaae 75 1000 1,1 -Diehloroethaae 100 1,2-Diehloroethaae (athylana dichlorida) 100 1,2-Dichloroethylene 200 Dichloroetbyl atbar 15 Diebioronoaofluo roroathan# 1000 1,1 -Dichloro-1 -nitroethane 10 Dichlorotetrafluoroetbaae 1000 Diatbylamisa 25 Dlfluorodibromomethaae 100 Dllaobutyl katona 50 Dimethylaailine (N-dlmetbylaalline) - akla 5 Dimethylformamide 20 1,1-Dlmathylhydraalaa - akla 0. S Dimethyl aulfata - akla 1 Dlpropylaaa glycol matbyl atbar 100 Dioxaae (diethylene dioxide) 100 Ethyl acatata 400 Ethyl acrylata - akla 25 Ethyl alcohol (ethanol) 1000 Ethylamlaa 25 Ethylbaaxaaa 200 Ethyl bromide 200 Ethyl chloride 1000 Ethyl atbar 400 Ethyl formate 100 Ethyl ellicate 100 Ethylaaa chlorohydrla - aklai 5 Ethyleaedlamiaa 10 Ethylaaa dlbromida (1,2-dibromoethane) 25 Ethylaaa lmlaa - akla 5 Ethylaaa oxide 50 Fluorine 0.1 Fluorotrlchloromethane 1000 Formaldehyde 5 Furfural 5 Furfuryl alcohol 50 Gaaoline 500 ieptane (n-heptana) 500 iexane (n-hexane) 500 Hexanone (methyl butyl katona) 100 Hexone(methyl iaobutylkatoaa)100 Hydraxlna - akin 1 Hydrogen bromide 3 Hydrogen chloride '5 0.7 90 22 1400 200 200 1350 0.3 240 0.1 300 450 4950 400 400 790 90 4200 60 7000 75 860 290 25 60 1 5 600 360 1400 100 1900 45 870 890 2600 1200 300 850 16 30 190 9 90 0.2 5600 6 20 200 2000 2000 1800 410 410 1.3 10 7 Hydrogen cyaalde - akla Hydrogen fluoride Hydrogen peroxide, 90% 10 11 32 1 1.4 Hydrogen eulfide Iodine 0. 05 20 0.1 0.2 30 1 leophorone 25 140 laopropylamlna Mealtyl oxide ' Methyl acetate Methyl acetylene 5 25 200 1000 12 100 610 1650 Matbyl acrylate - akla 10 Methylal (dimethoxymethane) 1000 35 3100 Methyi alcohol (methanol) Methyl bromide - akin 200 260 20 80 Methyl eelloaolve (2-metboxyethaaol) 25 80 Methyl calloeolve acetate (ethylene glycol moaometbyl ether acetate) 25 120 Methyl chloride 100 210 Methyl chloroform (1,1,1 trlchloroethaae) 500 2700 Methylcyclohexane 500 2000 Methylcyclohexanol 100 470 Methylcyclohexaaoae 100 460 Methyl formate Methyl laobutyl carbiaol 100 250 (methyl amyl alcohol) 25 100 ft-Methyl etyreae 100 480 Methylene chloride (dlchloromethane) Monomethyl aniline - akin Naphtha (coal tar) 500. 2 200 1750 9 800 Naphtha (petroleum) Nickel carbonyl Nitric acid p-Nitroanlliae akla Nitrobeasena akin Nitroatbaaa Nitrogen dioxide Nitroglycerin Nitromethane 2 -Nitropropane Nitrotoluene - akia 500 2000 0.001 0. 007 10 25 16 15 100 310 59 0.5 5 100 250 25 90 5 30 Octane Oeone Pentane 500 0.1 1000 2350 0.2 2950 Pentanoae (methyl propyl ketone) Pe rehloroetbylene 200 700 (tetrachloroethyleae) Phenol - akia . Pheaylbydraaiae - akla 100 670 5 19 5 22 14 Phoephine Phoephorua trichloride Propyl acetate 0.05 0.5 200 0. 07 3 840 Propyl alcohol (laopropyl alcohol) 400 980 Propyl ether (laopropyl ether) 500 2100 Propylene dichloride (1,2-dlehloropropane) 75 350 Qaaea and Vapor* (cont.) ~ Substance PPM Approx. Mg. par Cu.M. _ Subatanca Approx. Mg. PPM par Cu.M. Propylana Imina akin Propylaaa oxide Pyridine Quiaona Stibina Stoddard aolvaat Styrana monoraa r (pbanylathylana) Sulfur dloxida Sulfur hexafluoride Sulfur monocbiorida Sulfur pantafluorida 1,1,2,2-Tatrachloro- athaaa - akin . 100 5 0.1 0.1 500 60 240 15 0.4 0.5 2900 100 5 1000 1 0.025 420 13 6000 6 0.25 .5 35 Tatrahydrofuran Tetranitromethane Toluana (toluol) o-Toluldina akin Tolylene-2,4-diiaoeyanate Trichloroathylona Triethylamina Tr ifluoromonobromomathana Turpantlno Vinyl chlorida (chloroatbylana) Vinyl toluana Xylene (xylol) Xylldine - akin 200 590 1 200 750 5 22 0. 02* 0.14* 100 520 25 100 1000 6100 100 560 500 1300 100 480 200 870 5 25 Probably sufficiently low to protect against primary sensitisation, but may not protact paraona specifically aanaltlaad. Puata, Fumaa and Mlsta Subatanca Mg. par Cu. M. Subatanca Mg . par CiuM. Aldrln (1,2,3,4,10,10-hexachloro-l,4, 4a,5,8,8a-hexahydro-1,4,5,8-di- methanonaphthalene) akin 0.25 Animate .(ammonium aulfamata) 15 Antimony 0.5 ANTU (alpba-naphthyl-thiourea) 0.3 Araanic 0.5 Barium (aolubla compounda) 0.5 Beryllium 0. 002 Cadmium oxide fume 0.1 Calcium araanata 0.1 Chlordane (1,2,4, 5, 6,7, 8, 8-octa- chloro-3a, 4, 7, 7e-tetra-hydr-4, 7 -m cthanoindane) 2 Chlorinated camphene, 60% 0.5 Chlorinated diphenyl oxide 0.5 Chlorodlphenyl (42% chlorine) - akin 1 Chlorodiphanyl (54% chlorine) - akin 0.5 Chromic acid and chromatea (aa CrO,) 0.1 Crag herbicide (sodium 2-(2, 4-dichloro- phenoxy) ethanol hydrogen eulfate) 15 Cyanide (aa CN) - akin 5 2,4-D (2,4-dicklorophenoxyacetlc acid) 10 DDT (2.2-bia (p-chloropbenyl)-l, 1,1- trichloroethane) 1 Dieldrin (1,2, 3,4,10,10-hexachloro-6, 7-epoxy-1,4,4a,5,6,7,8,8a-octahydro - ` 1 ,-4, 5, 8-dimethanonapbthalene) - akin 0.25 Dinitrobensena akin 1 Dinitrotoluene - akin 1.5 Oinitro-o-creaol - akin 0.2 CPN (O-athyl O-p-nitropbanyl thiono- bcnxenephoaphonate) - akin 0.5 Farbam (ferric dimethyl dithlocarbamale) IS Ferrovanadium duat 1 Fluoride ' 2.5 Hydroquinone 2 Iron oxide fume Lead 15 0.2 Lead araenata 0.15 Lindane (hexachloroeydohexane, gamma iaomar) Lithium hydride . Magnaaium oxide fume Malathion (O, O-dimethyl dithiophoephata 0.5 0.025 15 of diethyl mercaptoauccinate) - akin IS Manganeee 5. Mercury Mercury (organic compounde) - akin 0.1 0.01 Methoxychlor (2,2-di-p-raethoxyphenyl-l, 1,1 -trichloroethane) Molybdenum . IS (aolubla compounda) (insoluble compounda) 5 15 Nicotine akin 0.5 Parathion (O, O-dietbyl-O-p-nltrophenyl thiophosphate) - akin Pentachloronaphthalene - akin Peniachlorophanol - akin Phosphoric acid 0.1 0.5 0.5 1 Phoaphorua (yellow) Phosphorus pentachlorlde Phoaphorua pentaaulfida 0.1 1 1 Picric acid - akin 0.1 Pyrethrum 2 Rotenone Selenium compounda (aa Sa) 5 0.1 Sodium fluoroacatate (1080) - akin 0.1 Sodium hydroxide 2 Strychnine Sulfuric acid 0.15 1 TEDP (tetraethyl dithionopyro- phosphata) - akin 0.2 TEPP (tetraethyl pyrophoephate) akin 0.05 Tellurium 0.1 Tetryl (2,4,6-trinitrophenylmethyl- nitramine) - skin 1.5 Thallium (aolubla compounda) Thiram (tetramathyl thiuram diaulfida) 0.1 5 Titanium dioxida .IS III. Fumes and Mists (cont. 1 Substance Mg. Pr Cu. M, " Substance Mg. per Ca.M. Trlchloronapthalene - skin Trinitrotoluene - skin Uranium (soluble compounds) (insoluble compounds) Vanadium , <V25 duat> (VjOj fume) 5 1.5 0.05 0.25 0.5 0.1 Warfarin (3-(C<-acetonylbensyl)4-hydroxycoumarin) Yttrium Zinc oxide fume Zirconium compounde (as Zr) 0.5 $ 15 5 Radioactivity: For permiselble concentrations of radisotopea in air, see U. S. Department of Commerce, National Bureau of Standards, Handbook 69, "Maximum Permissible Body Burdens and Maximum Permis sible Concentrations of Radionuclides in Air and in Water for Occupational Exposure", June 5, 1959. Al so, see U. S. Department of Commerce, National Bureau of Standards, Handbook 59, "Permissible Dose from External Sources of Ionising Radiation", September 24, 1954, and addendum of April 15, 1958. Mineral and Non-Metallic Inorganic Duste Substance Silica Quarts high (above 50% free silica) medium (5 to 50% free silica) low (below 5% free silica) Cristobalite (above 5%) Amorphous Silicates Mica Portland Cement Soapstone Talc MPPCF 5 20 SO 5 20 5 20 50 20 20 Substance Miscellaneous: Aluminum Oxide Cal cite ' Dolomite Limestone Marble Silicon Carbide Other Inert Duets MPPCF 50 50 50 50 so 50 50 Tentative Values Substance PPM Acetonitrile 40 Allyl glycidyl etber (ACE) 10 Boron oxide tert. Butyl chromate (as CrQj) n-Butyl glycidyl etber (BCE) 50 Butyl mercaptan . 10 Chloroacetaldehyde 1 C biorobromome thane 200 DDVP (O, O-Dimsthyl-2,2- Dichlorodivinyl phosphate) Diglycldyl etber (DCE). 10 Dimethyl acetamide 10 Endrln (1,2,3.4,10.10-hexa- chloro-6,7-epoxy-1,4,4a, 5,6,7,8,8a-octa hydro-1, 4-endo, endo-S, 8-dimeth- anonapbthalene) Ethanol cm ins 0.5 Ethyl mercaptan 250 ulycidol . 50 Heptachior (1,4,5,6,7,8,8-hep- tachloro-3a, 4,7, 7a-tetrahydro- 4, 7-methanoindene) Approx. Mg. per Cu.M. Substance PPM Approx. Mg per Cu. M. 70 45 IS 0. 1 270 35 3 1050 1 55 35 0.25 1 640 150 0.25 sec-Hexyl acetate 100 Isopropyl glycidyl ether (ICE) 50 Ketene Methyl mercaptan 0. 5 50 1 -Nitropropane 25 Pentaborane 0. 005 Perchlorometbyl mercaptan Phenyl glycidyl ether (PGE) 0. 1 50 Phosdrin (2-carbomethoxy-1 methyl vinyl dimethyl phos- phate) n-Propyl nitrate 25 Systox 2,4,5T (2,4, S-trichloro- phenoxy acetic acid) Teflon decomposition products (as F) 1,2,3-Trlchioropropane 50 1, l,2-Trichloro-l,2,2-tri- fluoroethane 1000 Triorthocresyl phosphate Tripbenyl phosphate 590 240 0.9 100 90 0.01 0.8 310 0.1 110 0.2 10 0.05 300 7600 0.1 3 (Signed): William L. Ball W. Clark Cooper Herbert E. Stokinger Hervey B. Elkins Keith H. Jacobson Russel C. Scovill William F. Rsindollar Allan L, Coleman, Chairman