Document e7Qv7O2gawVLxk9ypkJXgrq29

Arrrg~ iH-sy Jah, 2 99 02: 02p DuPont-Chasbers Werks 609-540-4654 p .2 CC: B. H. Karrh, M.D. r j pu P ont de N em ours & C o m pan y W ilm ing to n. Delaw are g e n e r a m uyicm i om irrM iiiT - March 15, 1979 PERSONAL AND CONFIDENTIAL PCD. trGP . GILBY B-13265 i FLPORCOHSAUMLBFEARCSTAK0NRTKSSTUDY (Ref. Letter from RDR to PGG, 1/23/79) In response to our request to the plant for additional information to analyze the data statistically, we received a tab ulation of the Dispensary Visits and Disability Wage incidents in the exposed and control groups (Attachment V ) . These data were broken dovm by body systems. We were also informed of the number of employees in each group who had abnormal liver function tests. We performed a "chi-square" test to test the significance of differences between the exposed and control groups. The at tached table shows only those differences that were found to be statistically significant. In the category, "Allergic, Endocrine, and Metabolic" disorders, a significantly higher incidence was found in the exposed group for both Dispensary Visits and Disability Wage incidents. This was attributed in the report to a higher number of diabetics in the exposed group. The exposed group also showed significantly higher numbers for "mental and psycnoneurotic" disorders and for disorders of "skin and cellular tissues." The control group, on the other hand, had considerably, more Disability Wage incidents for circulatory diseases, 25 com pared to 5. This difference is highly significant (P< 0.001). Explanations for these differences cannot be found from the available data. It would be helpful to find out what specific diagnosis within these general categories accounted for the differences between the two groups. GK000378 --* YwtwAf %a/r AD6 nniwr. sampthimB AttOUT iSlSWftffSSSIWB--- .. GK000378 000141 I Pan. S6 99 02:02p DuPont-Chaabars Works -2 609-540-4654 P-3 Although the number of employees with abnormal liver function tests was notably higher in the exposed group (6 com pared to 1), the difference is not statistically significant (P < 0.05). Nevertheless, the data do suggest that the' exposed group may be at.an excess risk of developing liver disease, so continued surveillance would be advisable. MEDICAL DIVISION ASPt:tma csdh . Sidney Pell Manager Epidemiology Section GK000379 ( GK000379 000142