Document Z4Od2nad7bMVBRYOOY5rbp1QV

Message From: Sent: To: Subject: Beck, Nancy [/0=EXCHANGELABS/OU=EXCHANGE ADMINISTRATIVE GROUP (FYDIBOHF23SPDLT)/CN=RECIPIENTS/CN=168ECB5184AC44DE95A913297F353745-BECK, NANCY] 4/18/2018 12:18:06 PM Gillay, David [David.Gillay@btlaw.com] RE: Harmonizing TCE Efforts David, While we could send someone to participate in a broad widely attended workshop, this has more of the feel of a smaller planning meeting. OCSPP will take a pass on participating. Thanks for thinking of us. Nancy Nancy B. Beck, Ph.D., DABT Deputy Assistant Administrator, OCSPP P: 202-564-1273 M: Ex. 6 Personal Privacy (PP) ! beck.n3ncy@ep3.gov From: Gillay, David [mailto:David.Gillay@btlaw.com] Sent: Wednesday, April 18, 2018 7:43 AM To: Beck, Nancy <Beck.Nancy@epa.gov> Subject: RE: Harmonizing TCE Efforts G ood morning - please find our proposed a ge n d a for next M onday's m eeting. If you have any questions or need any further inform ation, please let m e know, dave Ex. 6 From: Beck, Nancy f mailto:Beck.Nancy@epa.qov1 Sent: Monday, April 16, 2018 12:21 PM To: Gillay, David S ubject: RE: Harmonizing TCE Efforts David, When its available, please share the workshop agenda and I can use that to see who the best participant from EPA may be. Sierra Club v. EPA 18cv3472 NDCA Tier 12 ED 002061 00051072-00001 Thanks, Nancy Nancy B. Beck, Ph.D., DABT Deputy Assistant Administrator, OCSPP P: 202-564-1273 heck.nancy@epa.gov From: Gillay, David [mailto:David.Gillay@btlaw.com1 Sent: Monday, April 16, 2018 12:19 PM To: Beck, Nancy <Beck.Nancy@epa.gov> Subject: RE: Harmonizing TCE Efforts Nancy - hope you had a nice weekend. Thanks so m uch for your follow up a n d I apologize for m y d e la ye d response (spring break w ith my senior son, etc.) It looks like w e are a g o for an initial m eeting in DC on 4/23. Do you have a senior staff or some one else you could d ele g a te to a tte n d or p articipa te on 4/23? dove David I. Gillay lam es and Thornburg IIP Chair, Rem ediation & R edevelopm ent 317-231-7474 (o) | Ex. 6 From: Beck, Nancy f mailto:Beck.Nancy@epa.qov1 Sent: Friday, April 06, 2018 10:10 AM To: Gillay, David S ubject: RE: Harmonizing TCE Efforts David, Thanks for thinking of me for this. I don't think that at this time it would be appropriate for me to be on the steering committee, but of course EPA will surely consider participation as appropriate in future workshop activities. Regards, Nancy Nancy B. Beck, Ph.D., DABT Deputy Assistant Administrator, OCSPP P: 202-564-1273 Sierra Club v. EPA 18cv3472 NDCA Tier 12 ED 002061 00051072-00002 beck.nancy@epa.gov From: Gillay, David [mailto:David.Gillay@btlaw.com1 Sent: Thursday, April 5, 2018 8:20 AM To: Beck, Nancy <Beck.Nancy@epa.gov> Cc: 'am a ierO; E r6 J pe7s~oT~arpriv~acyTpp)~ J ;>; 'Thompson, Rod B (rodnthom@iupui.edu)' <rodnthom@iupui.edu>; 'Ed Pfau' <epfau@hullinc.com>; 'Michael Dourson' <dourson@tera.org>; Clark, Becki <Clark.Becki@epa.gov> Subject: Harmonizing TCE Efforts Dr. Beck, g o o d m orning a n d I h op e you are having a nice w eek. In co o rd in a tio n w ith A nd y Maier, Mike Dourson, Rod Thompson, a n d Ed Pfau, w e w o u ld like to form ally invite you to p a rtic ip a te in a steering co m m itte e m eeting a n d workshop (at a d a te to b e d ete rm ine d soon, but hopefully in April) to d e ve lo p a c o o rd in a te d effort in co n n e c tio n w ith n o n -c a n c e r endpoints for TCE. We have prepared the following description to outline our thoughts, objectives, and path forward. Harmonizing Efforts to Address the Non-Cancer Regulation of Trichloroethylene in the United States Nationally, m any science and science policy efforts are underw ay atte m p tin g to im plem ent effective regulation of the n o n -c a n c e r endpoints of trichloroethylene (TCE). These efforts have illustrated the need for an e n h a n c e d understanding of n o n -c a n c e r toxico lo g ica l assessment, exposure q u a n tifica tio n a n d n o n -c a n c e r risk ch aracterization for purposes of risk m a n a g e m e n t. For exam ple, the p ra c tic a l a p p lic a tio n of n o n -c a n c e r risk assessment science is being explored through a national effort to characterize a key a sp e ct of U.S. EPA's Reference C o n ce n tra tio n for TCE th a t includes " up to an order of m a g n itu d e uncertainty," w h ich m ight define a "ra n g e " of a c c e p ta b le rem edial risk levels for risk m a n a g e m e n t decisions. Efforts are also u n d e rw a y to verify the findings of the Johnson e t a/. (2001) study a n d to dete rm ine the im plications of this study in the c o n te x t of the existing n o n -c a n c e r toxicolog y d a ta b a se . These efforts m a y m ore fully ch aracterize the p ote ntia l risk of feta l heart m alform ations, or confirm o th e r studies th a t d o not show this e ffe ct, through inhalation exposures to TCE in am bient air under different exposure scenarios. In 2013, the A lliance for Risk Assessment (ARA) led an initiative to e va lu a te risk-based decision-m aking based on the Reference C o n ce n tra tio n for TCE finalized by U.S. EPA in 2011 a n d published in IRIS. This effort resulted in a h alf-da y w e b c a s t w ith international participa tio n, a nd a g u id a n c e d o c u m e n t on the risk m a n a g e m e n t a t TCEc o n ta m in a te d sites.1 The evalua tio n also resulted in a published m anuscript (Dourson e t al., 2016)2 a n d m any o ther national, regional a n d local efforts to address the problems associated w ith risk m a n a g e m e n t of TCE. Five years a fte r the ARA initiative, it appears th a t a renew al w o u ld support harmonizing ong o in g TCE-related risk science efforts to b e tte r understand a n d re gulate the risks of exposure. A proposed first step in this effort is to c o n ve n e a steering co m m itte e to plan future activities to support harmonizing TCE risk assessment a n d m a n a g e m e n t. Such activities m ight include o pe n workshops, e d u c a tio n sessions, te c h n ic a l p ro je ct d e ve lo p m e n t, a n d o th e r outreach. We solicit your involvem ent in this effort as a steering c o m m itte e p a rticip a n t w ith an a n tic ip a te d n ear term c o m m itm e n t of a tte n d in g a planning m eeting in the Law Offices of Barnes & Thornburg LLP in W ashington D.C. (with a w e b in a r option) a n d a h a lf-d a y workshop. The m ain g oa l of this steering co m m itte e workshop is to share inform ation on efforts underw ay am ong stakeholders, have a brief overview of the work currently being done, and form a steering co m m itte e action plan to help guide future efforts and avoid duplication. We are looking a t scheduling this planning m eeting a n d workshop on the w e e k of 4/16, 4/23, or 4/25. Please let us know your preferred d a te a n d tim e as soon as possible so w e ca n sync our schedules. O nce a d a te is confirm ed, w e will circulate a draft a g e n d a for input. 1 Alliance for Risk Assessment (ARA). G uidance for C ontam inated Sites: Trichloroethylene (TCE) Risk Assessment Case Study. April 15, 2013. Sierra Club v. EPA 18cv3472 NDCA Tier 12 ED 002061 00051072-00003 'Dourson ML, Gadagbui BK, Thompson RB, Pfau EJ, Lowe J. M anaging risks of noncancer health effects at hazardous waste sites: A case study using the Reference Concentration (RfC) of trichloroethylene (TCE). Regul Toxicol Pharmacol. 2016 O ct 80:125-33. Thanks in a d v a n c e for your tim e a n d willingness to p articip a te , dave Ex. 6 I_____________________________ BARNES & A THORNBURG LLP CONFIDENTIALITY NOTICE: This email and any attachments are for the exclusive and confidential use of the intended recipient. If you are not the intended recipient, please do not read, distribute or take action in reliance upon this message. If you have received this in error, please notify us immediately by return email and promptly delete this message and its attachments from your computer system. We do not waive attorney-client or work product privilege by the transmission of this message. CONFIDENTIALITY NOTICE: This email and any attachments are for the exclusive and confidential use of the intended recipient. If you are not the intended recipient, please do not read, distribute or take action in reliance upon this message. If you have received this in error, please notify us immediately by return email and promptly delete this message and its attachments from your computer system. We do not waive attorney-client or work product privilege by the transmission of this message. CONFIDENTIALITY NOTICE: This email and any attachments are for the exclusive and confidential use of the intended recipient. If you are not the intended recipient, please do not read, distribute or take action in reliance upon this message. If you have received this in error, please notify us immediately by return email and promptly delete this message and its attachments from your computer system. We do not waive attorney-client or work product privilege by the transmission of this message. Sierra Club v. EPA 18cv3472 NDCA Tier 12 ED 002061 00051072-00004