Document QgGbe6e5559Qpzkva225M7eKv

MIN 'JTES of '.he HEALTH AND SAFETY COMMITTEE NATIONAL INSULATION MANUFACTURERS ASSOCIATION New York, N. Y. May 10, 1966 The meeting was called to order at 10:00 A, M. with the following in attendance: R. Cotts Yf. Van Derbeek J. Destafano F. Edwards H. Johnston R, Kahn. C. Sheckler J. M. Barnhart C-ustin-Bacon Mfg. Company Johns-Manville Sales Ccrp. Pittsburgh Fiate Glass Company Owens-Cornir.g Fiberglas Corp. The Ruberoid Como* anv Baldwin-Ehret-Hill, Inc. John5-Manville Sales Ccrp. NIMA C, Scheckler was elected acting Chairman cf the Committee. The Chairman was asked to be present at the Executive Committee Meet ing on May 24, 1966. Following background discussion relating to adverse publicity, etc., pertaining to asbestos and mineral fiber, the Committee agreed that the projects should be separated with respect to (a) asbestos and (b) mineral fiber. {a) The program pertaining to asbestos should be left with the Industrial Hygiene Foundation. This organization has sent a proposal to various companies for consideration, as per attachment. Other companies (than those listed in the April 15, 1966, letter) have since been asked to participate. A three year project is estimated to cost $175,000. (b) It was agreed that an independent agency be contracted with to study erosion with respect to mineral fiber duct liners and fibrous glass air ducts. It is estimated that the cost cf this program would approximate $25,000. The Committee agreed that NIMA should act as a clearing house for in formation relating to: 1. Adverse publicity 2. Code regulations 3. Public laws 4. education program with IDCNA (a) Preminm rates and excessive costs (b) Y.'crkman compensation claims (c) Health program Further, the Committee agreed that its function was to delve into the medical, research, engineering, publicity and legal aspects pertaining to health and safety problems concerning mineral fiber and asbestos. ADJOURNMENT There being no further business, the meeting was adjourned. Respectfully submitted Or J; M, Earnnart Indus Vk.al kyoISks rouN' w-.riON or amirr,:ca, inc. H I.-2I. I< Y17 V? , 4- " C1 FI :VTX Avf L? <t F*TTfc*.> UOH, Pa. l April 15, 196S Ml 4. V*' F II: Ids* .rd; Ivt r.. Grant J. K. Volfs ie C irt^in-fcced Products Core;satic?. Jeh'-.fi-i-itr.viilc- Cc rpcrttic-n O'.vsr.iCcrr.'lr.j Fiberglae CcrporxV...*:! Pittsburgh i s. r: Cla<s Coi-piny U. S. Rubber Company Attached ii xr. Industrial Hygiene Foundation ^sbeates and fibreglass tnreeyes.i rtitijth project proposal inccrporc tins uggee:ionf rr.tda by tho*e listed above vhc attended a ret'exrch planning meeting ir. rr:y c/fine cn April 12, IS66, Also enclosed i ? contractual .'greemer.t in an original end cue copy' in the event that sponsorship of this project is approved, boih should bt signed, the carbon returned and the original retained for the sponsor's fil^s. Robert T. P. deTrevillt, M.D. Mane, ring Director djl:t jc Enclos ures cc: Mr. Marshall Burch, O"oer.s -Cori.ir.c Fiberglis Corpcratlr Dr. C. S. Eiehop, Ower.s-Corning: Fiberglta Corrovttion f /7~S s (\ , t i t ~/~ -7 *A^ a* a*ooatc* or iaout<c rcw tms aova..ccc*t or utAuTxrui. v*c.T*ia oo*o.-tiom 'iK&USYftLV. MeLV&K ?*&y; :V}*T:U & V A ?-\ C f. i *'*<! Pi S. ? srFrt rlvV^&y^A, tg.fc'.S <A.vrii is, i ?'$?5--5 35r-.2 fas1 Aj; Ssi-vislif/t Jios c: & Sa c-f. A.s'hssiaj &-lt2 lad .b; `Tbi .uair of Tries f-cV ti*rxc5- A-5i>5ii.Wi ^yr.t, C^*9:IU AibasS-if'. tEtsTsCxucrs?^.nwsuvc< aTeaionryu* ,4>^**. c- r>>4; .m^ r cavi ls,s $Z;:. oi ths ps-epii Sixri Jr.ad eilj.i, la Laiplu-ii* Is. i. {rv'4 2-a*sv.UT<? cuj&^sUsI La, *5*jks?:z Ixt&tgg** is . fcLi li.g-.;, `Z'Lvr r,t/;:* s>i.'th;.1;r2";\ >*& s> pr.tviii^s o ''isbactcs b*lscM ttflang ts Lsif-is?4 d.?3>Sfcs Is Ml-.sal, Florida. C^.cs, Tcttsc sad {3> V^-'a-.L':5i SLa. i`1--1 J- sd iOv fcSiS-O^dASAiCt Ilik'clti-l CRCih.3 i3T ^hisL. acrtopsy psrnUsel&.'s. had bata ,ff.fcodict" It. K.ilj: itJ <r<jad ths.1 4C &f lha !^i las J?^"J rass&il;- stipssitd a 4?^ 5?GVi.iitri; Is Jib^i;r>sb?if2. `S'hiss lit ;U p?asaa.ic s. Is dcubi ti^-S "t.z'zisi&s bodl-ss*5 ftssifU ladle tiers c5 tbr, ish.sJz.ll2s. ei t- bisect filers. isab. bed's s have been iovsrd is cii riels.*:?;; ix.d Uis w;.?l'>~*2ra 'chi.::?, bs/ savs c&LUi ''pseudooasfccitca bodies." Rscs'tly Davic^ and Gbll-str^ tiavo cem$n.!?t:;i33& *" the tntrtesUultr dsvj.iepss:sS c-tiisritl. #* "r.cbssi'Ji bo<lioju s'sstr.ds.ry to amorphous #- at. cs? xai'jcara*: ?os r.< i3C *> r<* -:ii jriTv^ cr>-j._';.>s ezxsvnrx^ ix3v^'s./.u r.f-wis-z fcyxu/.vs^x c? Asl: ; ecct-lif as. resistor is !?? sV.'!`y tr rjcdsc* ysr C"::^^; c f-v : f~ ; d'/d^as ftfcsssh' ; 's?'.;.*$.s tis psfC&aaHsa. a' Ira- easesy, l; [? U'.:v.\v.iz i.7 zz $.11 z? cilice* Jaw bori el.:-.*? a to possess &`.s ability. Tao i'i:u:r- is ^srs;* ti lSs.U* it the trcmoiiij v&alV which If ssV'-wtOx fch; 'd*>cr b'.tjc hs j/istsm-^o`"sio tt z'szitAif. srlib; thi cvls.ir.s <r: '.. \s.:*.-;&i!- C'llUii-#} Li ? sc? ts>2 tey$*ti5:&?*! s&-striae fezi!;'. aci tfc: t:\Vi-&;. sivlty e fcli ds.'U *K'ii. A? rr.it s Li s set fccc. tLsr tiilcttis ctay ovt&r .'liX.a? r/.Liirr.si or s &&$iv*lv alieh? iri..v.i.ic-"7 -tb-s^.y f, xai eo::iiixI;- i?s iiiiApAt-.a cJ pr ;.*/ lij lux*; st,ai*-t Xs &.*.v.sL t e^rt^ls j-tlyzycllu Lydrs-earbeas std ts-aes CiiX^li Saisri. tc ba pc-t*r>t cftr-ci? "pz-od^sisp agoris br rs h-yd^Gvsj.r VJ.Sid lr s.r b<t0Cj pi'?6'c.vi*rly t'-ths: Rsd bixsep ;-:rs.a'. tl.; Tytiiiibb'ity oxict* tif-t*. is *?& CivStil cr-d/j? tL; polycyclic Lydrc'r.ii^l-r" .ir.ry fcs t.titly rsi-p^albla J;*r fe* &LssrY*a / 7hlc p-c;* Lbiiliy tc sup?-set 5 si by bi-c fiadLxjzi lr 2*L> s-sTs-.trt e: S>7fci sxd Tzv-rxr tr*dck lsiUci?d aha ptivc* 2*2 r-i e/ iurir css? I'.ViSic GiSi-dlics ,.:e-sstc? 'Vt.a E.S gTrstss ibis. ti.if, cd jp-spuda-tlcx,' This 'itj.j is crxirsri t? iss rapor1: o: Doll'-3'1' which L-tilc*.tsd t jrsi.tiy Iscrcsasd risb ? lusj essra? snsioss Sritlib r/v5?lss?o erp*:ctd tr fi.-ibx^ics dust rrhlis /abs'icfi?-c; tLo !iob*2St^3. 2. It i i-s&ast isYsaiisrtlos Is tltb-orstc^y c tb* JsdMf trif-I - Foundatioa, lusj caacorc wars fcua-i is rs.t3 osc-osad fc? 13 months to hi^h concostaaticns of chryjstiia d^rt.^r.^csssa ^.ts orrsoss-i to chryoctiij dus? ** 1 \ fcy th.;r isva rtt^itsTs InUad t-o davolop Irmj sasoo!?, b.2ro io a 3-a-od prob-ablilyy t iJie'Uk'fttA-. K'.u:?k> TiiOF axz*;&s.i& S r^tt. tV? cl.ry dust- Cut jrrc&isod Iv.r.j' essss? iwr.s ei^slflstsily dltrr** f i?c-rr_ > vf vdr ;-r..\ d'.i not hm fils afosi, II Is IHcsSy tht$ this 4li*2*n?s Is- r.;. i scslbi? c cUb-tl alley .j$.-Ll te tbs czVsotcs duot mantels c during tr.* tea:lave-is htariff irk;iU;: vs3?c *V-* ruddering th* iext reepiraVl*, Telt; flatbed hs.s rei fe<ssa us-ad by jiyavicsso l&rs'ttlfj.scyc. Klefesi bi l- k-s-z tau-d cs.-ps.tl* c-i p.'fjyic-slaj iv-as; cancs-e iis traes s^Si-e-vali. Aiksi.'S- tibosres tni !:.;* e.ya b*tk eLiik.M**? tbJ ladvcsTlsi, hssiib. 4jo::i .t: villi vftj&ss-* c- &*c& tty astSsrlsis has b* vastly dslijyoai, '.>otiry: tii^t.a. ass kata rspaassi la w^sksys ie gives iuii. ?-hsl>i s tks i'il <& fLLsesxatsv.:? sites is?.v Vasa lab-slid a? hijfLiy la tbs- i&y pr-sce by aiaoel-ssicr, vith tebsstca,; U ic a Izst that felVlvr.-v-h tL:- *.#i ?* c! litfc* glasi cv.il a iaj tea.?* of taluatlit has b* stsa^siad.- f'.X'llJ.r1 sbv'.fy has bias- cetd* the dv-cl ; i *lrf e vriskrail as. 6.;-L*zUt*{, r.',iL--? i'JlcSt . . FROy^gAL Phaos i. Xr U ta *s?Aiali3 the y* 3 pease- t s.-:t2sai3 dlifsrai* v Ix.crefc^U fierrve raturlsJa ef essxSrasti^g ch^triicsl- cesajcsltica, 5a ehi.?seJi?Li5 tki dl^arjitor */?i elniiieililjs La Iks essT>-s>a?3s PLj.SC 5. It Is cvop.issi to tcvasSi^ots lbs Issii'jaacs cf t?s.C3 tainersio and p-siy ^ ` r, . . cyclic hydroctr-bac* (1,3,, bt-nyopyrsas) aaaoeiaiad sritb oabcatoo ora or tk C'-bi squat p?c-c*5sla.r co. tko len^-t^yzc ?33i>-5c.sa sf Iks lung So tks t. f-NC'UtTH'.AU ^YCICKC rOUKCATtOH Of AMtHICA.INC. 4. Another objective of ii:i? phaao Ia to obtain dfl^inltlvo datf. sa the long* 4 Siria offset .? dust derived troe filf.mci tou* gl&3f wpoa thn lnja, Thres , varieties of such gi3s dust vriir ha lnvectlg?.tedi ... , lc t/llh tho pUenoNforvncLdehyrto-typo of binder 2, vlfci tl'-a binder urea iii textiles 3t tritivwt Mc4or. \ MyrsroALg PbiSQ A, ' The following fibrous nr.iitaxi&lc '/til b reduced to respirable particle lae (<3>J end 'will bn Injected la amounts of 3.5 raj. to 30 neg:. ar ntpuseus tuspcoptcos: 1. carysutil* duct (prey&red by tclliing in T'rlghr. mill wad 'alih demon rtratnd carcinogenic potential} 2. chryfotile dust (unroll led aynthstlc)* 3. aluminum nitride '4. trie ale lum phosphite (fU.amss*cuo) / 5. fibrous glaoe a.' vlth phenol-formcldahydotyp-a binder b. urith binder used fer tertian c. v^thout binder 6. ctfcarlua hydroaids (bruelio) 7. in la* r si vool 8. cine ride (filamentous) There materials trill bo ixjoctad intratraehekily ifcto iAznriora fcaeor other .r.9thaala. Previous oxp-trltncc hae dcincjcstraied that ao'osstoa bo.iioa trill form in resp^sao to chryretllo &isi crlthla sT/s zncmthz. The aulaMls Trill therefore ba hold for ela montha &r.d the a hilled. The lunjo t?Ul bo sxpaaded ^eilb bufforad formally under a hel d o v 10 cm. cf trator. Diochs removed fro.*?, thee lungr *crlll ba sectioned as 6/^ o Synthetic chrysotlls has been prepare i at Meilm jtaatltuta by Pr. V.r 111lata Gran^ulat. Electron photomicrographs choT/ ?hs chare.ct-ss.'l'JSlc tubul&j srys riyir -- Kra.cxi rou;.OA.Tif<h of a* cftiCA.uso. 5. if'-e: t.sxs.ii:\ unyrtinr.tiou. The. s sessions ^:U bi titLsd t> difiixcns 'rnaihout t..i ph^SoF*5T-h..sd sequcnL'.nL'y to provide crie*.ts for studyInc; mors compi e..?iv t'hs lisau* reteitea tc. this3 various mit^rlrly. Search lor ths ao-caliid tibifbr-di-ts will b* sn*.dp v.slag routinely stained sectiour, And section st/irsd fr>? Ircr. In idditlcsi* esits-lasd rs?tlez.s will b* er.md uac j.r CH-rr.-fUiel eend'.ilerc ir,z aabost** bfcdias. Tiv: iccisr gio'e* .whet txir.-.ts >c. be ti/s >ii*.uuar. Tci diii&rsar.i it. tistv* reictlro tb* synthetic chryistUs dust s--d tistt chic's is kiova t h flbsogaaic ts rroil is carcltrj* ale vill pcict io ti..t CiiSr-ibviici tc ps/thc jrac/.di-y tatdo by ct.x rnc,'`<. of ths varies tries which city Ia, kssooLMad iyis*. chrysctiii xiebistc? dust &r a rsaul: cf f rc'f esltij, Th* diY-Ieymsac of uasfcatcis l; vd'.-as1*', biXtts* to>rrnid ferritin bodies (Wolisie} tt> dusts ou':.tr rh.tr, asbestos -vould point to the non-specificity of . these structures and to ths desirability of collecting euch #tasbs8tc3 bodies11 from hurr.it lung; In order to subject f ism tc sloct-rco-procs i^elytis, Such snaiyils could plv* Laisrm?.tlic la rags-rd to tks eLeaclcsd ccnks-up cf th4 <tv.r.i responsible for thi Aaveiopaiett of the. ferritin body. Picas* 2. In ordtr tc explore the etlclogic role of the various corny ruentr cf chrysotila aobattoa La the production ci' luaj flbrccis and lung cancor, ria series of rets will be injected latratrtiheally with th; following: i 1, cfcryroiila dust knows. to ta ^orcfnojinic 2, syuthstic ehrysotiio t IhOJtTftlAL HYOICNC .TOUHOATICH CT AMERICA.tMO. 3. aynthctic chrysotiie plus nirkel 4. synthetic chrysotilc pluo nickel, plus benzopyrene 5. nickel alone or with carbon r.o carrlar 6. benxcpyrcne with carbon as carrier. These rat# will be hold for twe years and than, killed. The lunco srili be prepared for examination and sections cut In the same manner as In Phase 1. Three other series ol rats will bo Injected Intratrachsally -with tbs following dusts: 1. filamentous gls.se with phjnol-formaldehyde-type binder 2. filamentous glaae with thn binder used fer textiles 3. filamentous glass without binder. These animals will tl^o be held for two years f-nd then killed. The lungs will be prepared and studies as in the preceding group. The number of animals per aeries will bs ouch that thore will bs ac doubt regarding the statistical sigcificonco cf. tho rasuitn. / ' PROGRSSS REPORTS A prograss report givlx^ the rcralte of Phaeo 1 will be submitted at the end of 12 months, ' An interim report ca Phase Z will hs submitted at the ond c 24 a tnooths, and a final report will be subsisted at ';ks end of ths third ycaz. COSV The cost of this investigation Ir $10,000 por year for three yoars, or $30,000 for each of ths flvo participating companies. .. s . IfcOUfeTfclAi. KYICMC rOw'KCA?IOK CT SUPEP.v;si0N I-\tccarci will bo performed under ths direct cupervialon of Dr. Paul G.?o$t Director of the foundation'# Xleecarch Laboratory, The Fcundatior.'# atv.dias ot tabor too p recently are being conducted under partial support of the U.S. Government through & National Institutes of Health grant and a contract with the U.S, Public Health Service, Division 'of Occupational Health (Dr, Lewis J. Cr&lley), A list of D*. Gross' publication# in the pathology of pulmonary disease#, ar.cl a membership Information booklot describing laboratory project# presently In progress, aro attached. .. . wKi. xr\r>-> cr AMSRICA.IVC. I janFKp.':'Kr-r 4, t f Tncmjor., J. C., KefchiJa, R. C, C. ar.d M*cDonald, R. R. Asbestos t. Modern UrVar. Hcst.rd. S. Afr. Mod. J. 36:759, 1962. Taomtoi, J, C. Acb*fltc.3 ac<i tho Urban Dvellor In BlcltnU Ejects c' A*hteU>i, An.iale el Non? York Acade*r.y Sciences j?ril96, 1H5. Caunr, D., Totten, R. S. &rJ Oroas, P, Asbestos Boiicr Ir. Kckrtax; Lur.r* a* Autopsy. J.A-M.A. 2r?71 1963. V. cbt*r, 1. ar.d Chat^iduki*. M3r.clcenca of Asbestos E^poe-crc* pp. 2<jr Atvrvjvl Report or. Medical Research 1965*1964. GSUl GpecU.l Report, Pretoria, f, A/rlcct 1965. a Davie, J\ M. Q. Electron Microscopic Givdioe of Aobeatocis la Kji cad Ar.imfJ.6 la Biologic EiCecto of Aouoetoa, Aar.alt c* Navr York Ac&dcsny of Scicnc*ft 15?:93, 1965. Collet. A.. Personal connrsrar.lcat'rn to Dr. Gross, 1964. r*vn, D. C. and Tiniw:, T. D. ^jldBmlOicjical Srody of L*ru C-iaos? In Aebeetos Miners, AreB, Iad-ast, ge&lfc 17:654. 195$. , / \ '' Doll, R. Mortality from Lunj C-:cT:"oy is Aabestco Y'ork-ar*. Srifc. J. Induet, Med. 17:61, 1955, / ;;;