Document M91Lw0pgY4ob985Qm2BQ91dM

Office of Researd ED 002061 00269049-00001 Description -- Cross-Federal Agency information sharing workshop on PFAS -- Sponsored by Toxics & Risk Subcommittee* -- NIH Campus, Bethesda, MD February 5 - 6 , 2018 Objectives -- Workshop participants will emerge with: Better understanding of current PFAS state of science and knowledge gaps across participating federal agencies Operational-level cooperation and collaboration among decision-makers and those who are effecting the science at the lab bench and in the field *The Toxics & Risk is a Subcommittee of the National Science and Technology Council's Committee on Environment, Natural Resources, and Sustainability; Co-chaired by DoD, EPA and NIEHS 2 Sierra Club v. EPA 18cv3472 NDCA Tier 10 ED 002061 00269049-00002 Format: -- Opening remarks by senior government leaders (NIEHS, CDC, ERA, DoD) -- Historical perspective: EPA's Office of Water -- Panel discussion: Issues confronting state health officials -- Plenaries: Overview; Health Science; Exposure Science; Remediation; Risk Assessment -- Breakouts: Exposure Science; Health Science; Remediation and Treatment -- Final session with path forward; of particular interest for the T&R # Common knowledge basis to inform policy-makers within federal agencies; # Report-out list of needs to inform future federal PFAS strategy; and # Continued open communication among agencies Participation: -- About 200 participants -- Several regulatory and non-regulatory agencies, e.g., DoD, EPA, CDC, NIH/NIEHS, NIST, FDA, NIOSH, USGS, NASA, NOAA, OMB, ECOS/ITRC Proposed Outcomes: -- Public Report (contingent on continued T&R Subcommittee existence) -- Continued collaboration under the T&R working groups or independently 3 Sierra Club v. EPA 18cv3472 NDCA Tier 10 ED 002061 00269049-00003 EPA Panelists: State health officials from NC, CO, PA, NH Some (not all) of the issues identified: -- State-specific health advisory levels are a substantial challenge; need a uniform health advisory at federal level -- Reference Dose (RfD) levels or cancer slopes needed -- Developing health advisories - communications with states prior to release -- Need for standardized testing approaches -- Need for remediation methods -- Conducting biomonitoring in blood; what does it mean?- risk communication -- Communication tools to engage health care providers -- Concerns with other sources, e.g., food -- Identifying routes of exposure -- Need for a shift away from chemical by chemical assessment -- Communicating the meaning and consequences of low exposure levels -- Identifying vulnerable populations 4 Sierra Club v. EPA 18cv3472 NDCA Tier 10 ED 002061 00269049-00004 Centralized source of PFAS standards -- Define the chemical landscape for consistency Define relevant human health end-points or adverse outcomes -- RfDs and slope factors Explore and define relevant ecological end-points or adverse outcomes Epidemiological studies to assess associations between exposures and defined human health endpoints *From plenaries, breakout sessions and close out discussions Sierra Club v. EPA 18cv3472 NDCA Tier 10 ED 002061 00269049-00005 Which specific PFAS will EPA and NTP use for Tier I and Tier II testing? What type of data/information will be generated from this testing and subsequent utility? Data generation for prioritizing PFAS with greatest potential risk Access to non-public toxicity and exposure information Consistency and comparability across data sources *From plenaries, breakout sessions and close out discussions Sierra Club v. EPA 18cv3472 NDCA Tier 10 6 ED 002061 00269049-00006  Analytical methods for non-drinking water (DW) media (consistency in approach) Relative source contributions and exposure pathway-specific contributions Exposure route-specific mode of action Identification of precursor and transformation product relationships Point of use remediation methods Cheaper/faster methods to support remediation monitoring *From plenaries, breakout sessions and close out discussions Sierra Club v. EPA 18cv3472 NDCA Tier 10 7 ED 002061 00269049-00007  PFAS issue represents an opportunity for the use of new alternative methods to assess exposure and hazard and conduct risk assessments Visual research activity resource, "who is doing what, where" Centralized, cross-Federal government database available to states and communities -- Study results -- MS Library -- Precursor and transformation products Improved risk communication -- Consistent, easy to understand -- Translation to understanding *Within the purview of the T&R Sierra Club v. EPA 18cv3472 NDCA Tier 10 8 ED 002061 00269049-00008 T & R Subcommittee Co-Chairs: Bindu Nair (DoD); Christopher Weis (NIEHS); Ron Hines (EPA) Executive Secretary: Jennifer Coughlin Science and Technology Fellow: Caitlyn Mcguire Hosts: NIEHS/NIH Speakers and Participants Disclaimer: The views expressed in this presentation are that of the presenters and do not necessarily represent the views and/or policies of the U.S. Environmental Protection Agency. Sierra Club v. EPA 18cv3472 NDCA Tier 10 ED 002061 00269049-00009