Document 91a3djR1GJgL8D3kXBDqjy8yR

Katherine E. Reed, Ph.D. Staff Vice President 3M Environmental. Health and Safety Operations S'eus - 0106 - oo 573 A(L a a - 3667 p. 1 '-tOO Bush Avenue. Budding 42-2E-26 PO Box 3333 I St. Paul. MN 55133-3331 651 778 4331 Mm Certified Mail June 29, 2006 * * H o c mC o if lt o / , CNTAIi\j f, CB/ Document Processing Center EPA East - Room 6428 Attn: Section 8(e) Office of Pollution Prevention and Toxics US EPA 1200 Pennsylvania Avenue NW Washington DC 20460-0001 89060000377 S90b000 03 Re: TSCA 8(e) Substantial Risk Notice: Sulfonate-based and Carboxylic-based Fluorochemicals, Docket Nos. 8EHQ-1180-374; 8EHQ-0381-0394; oOV 8EHQ-0598-373 - Pilot Study to Assess Serum Fluorochemical Concentrations in American Red Cross Blood Donors, 2005. = "-o~px-*t. t Dear Sirs: cn ^ .rn Cui 3M is submitting this notice to supplement its previous submissions on sulfonyl and carboxylic*-' based fluorochemicals. 3M has recently received the enclosed final report for serum ^ fluorochemical concentrations in a small sample population of American Red Cross bloed donors in 2005. The purpose of this pilot study was to determine whether general population PFOS and PFOA concentrations, as measured in 2005 in a small sample of American Red Cross blood donors, may represent a decline from prior general populations measurements made in 2000. The study found that there was an approximate 50 percent decline in serum concentrations of PFOS and PFOA consistently observed across sex and two age categories for both PFOS and PFOA. 3M does not believe that these data indicate a "substantial risk of injury to health or the environment." Nevertheless, 3M has decided to report these data, recognizing the ongoing work by U.S. EPA to assess fluorochemical exposure pathways and potential risks. If you have any questions, please do not hesitate to contact Dayna Blomquist at 651-736-5413. Sincerely Katherine E. Reed Staff Vice President Environmental, Health and Safety Operations f