Document 8RxDvraa13QzXdOyLR9DedBVa

TO: Gerald Uptain JJH: JCtr Te& (HF XF: XwJW Interoffice Communication FROM: DATE: SUBJ: Tom Grumbles November 21, 1984 HEALTH AND SAFETY DATA FOR CAB-O-SIL VISTA Enclosed is a MSDS and other technical information on Cab-O-Sil. This product is an amorphous^ silica with sub-micron particle size and a density of 3-5 lbs/ft . Cab-O-Sil is inherently non-toxic (toxicity data summary enclosed) and the potential inhalation hazard would be our main concern. The product is amorphous containing little or no quartz. As such it does not have the silicosis producing capability of other silica dusts. The sub-micron size makes it highly respirable. However, it's low density would probably prevent significant settling of the dust in the lower lungs. The applicable TLV for this product is 20 mppcf. Due to the physical properties of this product a particle count determination is more applicable than a gravimetric determination. The following questions need to be answered if the plant decides to use this material. 1. Can the existing dust control systems contain and filter a dust of sub-micron size? 2. How can we best evaluate employee exposures to this product? We are not currently capable of particle count determinations. 3. If respiratory protection is necessary for safe handling what type of filters are necessary to efficiently remove sub-micron particles? The importance of these questions will be clearer once the decision is made on a handling system and the product delivery quantities. Then we will have a better idea of the potential for dust exposures to occur, and necessary exposure controls. Thomas G. Grumbles ajo 005 Attachment cc A1 Sather, John McCulley, Steve Saborsky VVV 000016165 CODE Information about Cab-O-Sil fumed silica, a Cabot performance chemical. CAB-O-SIL* MATERIAL SAFETY DATA SHEET DATE ISSUED July 1981 IISSUED BY Regulatory Compliance Office CHEMICAL NAME OR COMPOSITION Silicon Dioxide, Amorphous TRADE NAME & SYNONYMS CAB-O-SIL Fumed Silica, Colloidal Silica, Pyrogenic, Amorphous, Synthetic Silica CHEMICAL FAMILY MOLECULAR FORMULA Oxide SiOe HAZARD RATING /^FIRE Xo/\ < 1 X0 > HEALTH / n. REACT. CAS NO. 7631-86-9 COMPONENT Silicon Dioxide (Amorphous) PERCENT 99 plus PERMISSIBLE EXPOSURE LIMIT 20 mppcf SHORT TERM EXPOSURE LIMIT DOT HAZARD Non Hazardous PHYSICAL CHARACTERISTICS SECTIONjnSPHySICAEDATA? Fine White Powder, Odorless BOILING POINT NA VAPOR PRESSURE (mm OF MERCURY) NA VAPOR DENSITY (AIR = 1) NA FREEZING POINT NA SPECIFIC GRAVITY (WATER = 1.0) 2.2 pH 4.0(4% Aqueous Slurry) SOLUBILITY IN WATER , , ,, Insoluble ^fe^^l^^^^^^SECTlONIV^FIRE AND EXPLOSION HAZARD FLASH POINT (SPECIFY METHOD) FLAMMABLE (EXPLOSIVE) LIMITS (PERCENTAGE BY VOLUME) LOWER EXPLOSIVE LIMIT UPPER EXPLOSIVE LIMIT NA NA NA FIRE EXTINGUISHING MEDIA NA SPECIAL FIRE FIGHTING PROCEDURES NA ,NUSUAL FIRE AND EXPLOSION HAZARDS See Section IX VVV 000016166 TOXICITY ACUTE EFFECTS OF OVEREXPOSURE CHRONIC ^SECTION V - HEALTH HAZARD Non-Toxic LD50=Greater than 5000 mg/kg (oral) Temporary Discomfort Unknown EMERGENCY AND FIRST AID PROCEDURES Eyes & Skin: Flush with plenty of water. GENERAL REACTIVITY If irritation or discomfort persist, consult a physician. ECTIQ NVK,REACTIVITY DAT7F Stable 1 HAZARDOUS POLYMERIZATION None CONDITIONS TO AVOID NA VIUSP1LL PROCEDURES 7-DISPOSAL-REOUIREMENTS STEPS TO BE TAKEN IN CASE MATERIAL IS RELEASED OR SPILLED Spilled CAB-O-SIL is not a hazardous waste under U.S. Federal RCRA Regulations. WASTE DISPOSAL METHOD Can be swept up, flushed or vacuumed for normal disposal. CONTAINER DISPOSAL Ordinary method for non-hazardous waste. EYE PROTECTION ISECrflQN^HigSPcrA\^ Safety goggles recommended GLOVES Not necessary RESPIRATORY Approved dust respirator recommended for concentration above TLV (20 mppcf) VENTILATION Adequate for dusty environments OTHER NPCA-HMIS CODE E ECTfON lX?SPECIAL7PRECAUtidN! Dry powdered materials can build static electrical charges when subjected to friction. Proper precautions, when using CAB-O-SIL in the presence of flammable or explosive liquids, should be taken to prevent accidents. (See NFPA-77 Static Electricity) ^^^?^3S^^?SECTIONXr SHlPPING REGULATIONS (D.O.T. NOMENCLATURE) PROPER SHIPPING NAME CAB-O-SIL fumed silica is not-restricted/non-hazardous HAZARD CLASS NA TYPE OF PACKAGING NA LABEL NA PLACARD NA MARKING NA EXEMPT NA VVV 000016167 ____ 2M 1-1-84 Heaiih ana safety data TOXICOLOGY CAB-O-SIL fumed silica is amorphous and does not possess the ftbrogenic potential of many crystalline silicas. Experience over the past 24 years of manufac turing fumed silica shows not a single complaint case of lung fibrosis or loss of pulmonary functions due to siiica inhalation. Recent tests with laboratory animals have given the following results: Acute Oral Toxicity CAB-O-SIL fumed silica was ad ministered by oral gavage to 10 aibino rats at dose levels of 5 grams per kilogram of body weight following methodology described in 44 FR 44054, Part 772.112-21. All animals survived the 14 day duration of the study. When tested under the stated conditions, the Oral LD-50 for CAB-O-SIL fumed silica is greater than 5g/kg. Primary Dermal Irritation CAB-O-SIL fumed silica was evaluated for primary dermal irritation potential when applied under impervious bandages to clipped, Intact, and abraded skin of albino rabbits by the methodology described in 44 FR 44054, Part 772.112-25. The Primary Irritation index was calculated to be 0.44 on a scale of 0-8. The fumed silica was considered inert to mildly irritating. Primary Eye Irritation CAB-O-SIL fumed silica was evaluated for primary eye irritation potential when instilled in the eyes of rabbits by the methodology described in 44 FR 44054, Part 772.112-24. The mean Primary Eye Irritation Scores for unwashed eyes were 1.0 and 0.3 (in a scale of 0-110) after 24 and 48 hours respectively and 0.0 for the duration of the test. Scores for washed eyes were 0.0 throughout the 7 day test period. The fumed silica was considered inert to very mildly irritating. Acute Dust Inhalation (4 hr. Gravimetric) A group of 10 test animals (rats) was exposed to an atmosphere with a gravimetric concentration of 2.08 mg/1 (nominal con centration 59 mg/I) of CAB-O-SIL fumed silica for a 4 hour period followed by a 14 day observation period. No animals perished during the exposure or in the 14 day period after exposure. At necropsy, no gross lesions were observed. When tested under the stated conditions, the LC-50 for CAB-O-SIL fumed silica is greater than the gravimetric concentration of 2.08 mg/I or nominal concentration of 59 mg/I. REGULATORY STATUS CAB-O-SIL fumed silica in Foods The use of CAB-O-SIL fumed silica has been approved by the Food and Drug Administration for many food applications as both a direct food additive at levels up to 2 percent by weight and as a substance allowed in the manufacture of aterials that come into direct contact with food in ,-ious producing, manufacturing, packing, preparing, transporting, and holding operations. Pertinent sections can be found In Title 21 Code of Federal Regulations, Part 172 "Food Additives Permitted for Direct Addition to Food for Human Consumption." Food Chemicals Codex CAB-O-SIL fumed silica meets ail of the requirements for "Silicon Dioxide" (Synthetic Amorphous Silica). Lot analysis available upon request. CAB-O-SIL fumed silica in Cosmetics CAB-O-SIL fumed silica has been authorized by F.D.A. for use In cosmetic products. CAB-O-SIL fumed siiica In Pharmaceuticals CAB-O-SIL fumed silica has been authorized by F.D.A. for use in pharmaceutical products for internal and topical applications. USP-Nationai Formulary CAB-O-SIL fumed silica meets all of the requirements for "Colloidal Silicon Dioxide" as described in the USP-Natlonai Formulary. Lot analysis available upon request. ERA Status CAB-O-SIL fumed silica is registered in the EPA/TSCA Inventory as Silicon Dioxide, C.A.S. #7631-86-9; EPA Code A-343-7356. Hazardous Materials Act (P.L 93-633) CAB-O-SIL fumed silica is classified as a non-hazardous, non-restricted substance under the provisions of the Act of 1977. Federal Labeling Act CAB-O-SIL fumed silica meets ati of the requirements of this Act with respect to exemp tions from Hazardous Labeling. HANDLING AND STORAGE Handling Since CAB-O-SIL fumed silica is a dry powder material, we recommend the following for maximum comfort and safety: 1) Avoid continued excessive inhalation. Fumed silica dust levels should not exceed an 8 hour time weighted average dust exposure of 20 million particles/cubic foot (OSHA standard) or 10 mg/cubic meter (ACGIH proposed standard). 2) Provide adequate ventilation of the work area. Where ventilation is not available, use an NIOSH approved dust mask. 3) Wear eye protection. 4} Extended exposure to fumed silica dust may dry skin, hence protective skin oils and gloves are useful. 5) Clean up of CAB-O-SIL fumed silica spills can be handled using a broom, vacuum, or wet absorbent materials. 6) Dry powders, such as CAB-O-SIL fumed siiica, can build static electrical charges when subjected to friction by pouring, conveying, or mixing. Proper safety precautions, including electrical grounding, inert atmosphere, etc., should be taken when handling near flammable or explosive liquids. For further information see NFPA-#77, 1977, "Static Electricity." Storage CAB-O-SIL fumed silica should be stored in a dry environment, away from chemical vapors, to main tain its purity and properties. Cabot will supply Material Safety Data Sheets for CABO-SIL fumed silica and provide additional recommen dations for handling our products in your plant if requested. Compliance with the various regulations of OSHA, EPA, FDA, and other Federal Agencies, as well as those of State and Local Agencies, is incumbent upon the user. 10 VVV 0 0 0 0 1 6 1 6 8 0 9 Grades of Cab-O-Sil i CAB-O-SIL fumed silica is available In several grades, which vary in surface area, bulk density and thickening efficiency. Typical properties of CAB-O-SIL fumed silica grades are shown in Figures 13 and 14. Grade Standard Densed L-90 L-90D LM-130 LM-130D LM-5 LM-7 M-5 MS-7* PTG MS-55 HS-5 MS-75 EH-5 S-17 i 1f ! i I Surface Area (mJ/g) : Primary Particle Diameter (Microns) 90 + 15 130 15 V . . .024 " . : .018 . ;160+15 . : .016 : 200 + 25 200 20 .014 . - .014 250 + 20 .. 325 25 : ' .380 30 '- : .on r .008 ; ..007 Bulk Density (lbs/ft3) Standard Densed : Loss on Heating (Max. % @ 105*C) \ . '3 ,5 0.5 -.-v'-'v.' - - - - -r'r.3 .3 2 2 5. - 5....... -\. .-T* : -1 : ~v. : ;\ I -1.5 .. ;1-5 .. :2 5 v; ij5 Loss on Ignition . " (Max. % @ 1000 *q . :1 `1 -2 - 2 ' /2 Thickening Efficiency (Standard Grade) . ~ Low Moderate Moderate T. *'*.'*, ' - 'Also available in superdensed form, MS-7SD, at 10 Ibs/cu ft. High --------- * ' . Very High High '- 22 -- -:+-5 - .71 .)> 1 5 v-1.5 2 V '* - - ~vtr\ -.High v.: i - 2.5 ..Very -.High . Fig. 13 -- Typical Properties for Various Grades .. -----*; '*M . _ ... .. '- Property -f pH (4% Aqueous Slurry) 325 Mesh Residue (%) Specific Gravity - Refractive Index X-Ray Form Assay (% SiOa) Typical Values . 'v 3.6-4.3 0.02 Max 2.2 - 1.46 Amorphous - >99.8 - Fig. 14 -- Typical Properties (or All Grades *. ' /r- 00l 6*69 11 Introduction Properties of Cab-O-Sil Manufacture Cab-O-Si! is fumed silicon dioxide, a material which is generally regarded as unique in industry because of its unusual particle characteristics. Cab-O-Sil's ex tremely small particle size, its enormous surface area, its high purity and its chain-forming tendencies set it apart in a class of its own. So useful has Cab-O-Sil become -- in so wide a variety of products -- that a Cab-O-Sil sample is a standard item on most laboratory shelves. Yet almost every day, someone finds a new way to use Cab-O-Sil. Foremost among Cab-O-Sil's several contributions to product performance is its ability to modify a product's flow properties by building a three-dimensional network which alternately forms and disrupts in response to the degree of shear forces present -- thereby controlling flow characteristics in accordance with the formulator's exact requirements. At the same time the success of Cab-O-Sil in simul taneously enhancing several different properties of a formulated product makes possible distinctive chemi cal creations which would be difficult to achieve with any other single material -- or even with the costly addition of several materials. Combinations of thickening, thixotropy, suspension of solids, and optical clarity, for example, have been obtained in such diverse products as coatings, ad hesives, cosmetics, inks, plastics, and rubbers. Cab-OSil's action to promote free flow of dry powders, gran ules and pellets has been beneficial in foods, cosmetics, and chemicals. This general brochure is intended to (1) introduce the researcher to Cab-O-Sil and the properties it can impart to both liquid and dry systems, and (2) aid him in evaluating Cab-O-Sil in his own formulations. For certain industries and functions, special brochures have been prepared to aid in identifying the areas where Cab-O-Sii can help improve product and process effectiveness. Cab-O-Sil is produced by the hydrolysis of silicon tetrachloride vapor in a flame of hydrogen and oxygen, as shown in the reactions: (1) : 2Hz + 02 -------- 2HzO (2) : SiCU + 2HzO--------------------------- - Si021 + 4HCIT (Overall reaction): 1Hnnon SiCU + 2H2 -p 02------ ----------------- `Si02 i + 4HCI T In the combustion process, as shown in Figure 1, molten spheres of silica are formed. The diameters of the silica spheres are varied through process param eters from averages of 7 to 30 millimicrons. This pro duces grades with final surface areas ranging from 400 square meters per gram through 100 square meters per gram, respectively.* These molten spheres, termed primary particles, collide and fuse with one another to form branched, three-dimensional, chain-like aggregates. As the aggregates cool below the fusion temperature of silica (approximately 1710C.) further collisions result in some reversible mechanical entanglement or ag glomeration. Further agglomeration also takes place in the collection process. The residua! adsorbed hydrogen chloride on the Cab-O-Sil surface is then reduced to less than 200 ppm by calcination. Certain Cab-O-Sil grades go through an additional proprietary densing process which raises the bulk density from its normal average value of 2 pounds per cubic foot to more than 4 pounds per cubic foot, depending on the grade. 1 Surface areas are measured by the nitrogen adsorption method ol S. Brunauer, P. H. Emmet, and E. Teller, J. Am. Chem. Soc., 60, 309 (1938), and primary particle diameters are calculated from these, assuming spherical particles. Light, fluffy, pure white Cab-O-Sil, piled on a laboratory micro-spatula. 2 VVV 00001&170