Document 6R5LEg1JygYeeeQe7wZY7mONd

3M Specialty Materials 6 7 * f( January 29, 2003 3M Center St. Paul, MN 55144-1000 651 733 1110 m 0<Z03- 0!57g FYI-00-001378 FYI-00-001378 VIA FEDERAL EXPRESS l0 7 2003FEB 19 A M I h O l Document Control Office (DCO) Office of Pollution Prevention and Toxics (OPPT) US Environmental Protection Agency EPA East, Room 6428 1201 Constitution Avenue, NW Washington, DC 20460 Attention: Docket No. AR-226 and the FYI Docket Dear Sir or Madam: This continues 3M's voluntary submissions of data on perfluorooctane sulfonates and related compounds, as part of our ongoing dialogue with EPA regarding fluorochemicals. Included in this submission are the following: 1. Assay Validation Report, Quantitative Determination of PFOS, PFOSA, PFOSAA, N-MeFOSE-OH, N-EtFOSE-OH, POAA, and PFHS in Human Serum by LC/MS/MS, Northwest Bioanalytical (NWB), Study No. NWBS98-082, Report No. NWBR99-005, May 13, 1999. 2. Assay Revalidation Report, Quantitative Determination of PFOS, PFOSA, PFOSAA, POAA, PFHS, M556 and M570 in Human Serum by LC/MS/MS, Northwest Bioanalytical (NWB), Study No. NWBS00-040, Report No. NWBR00-108, January 24, 2001. 3. Assay Revalidation Addendum Report, Quantitative Determination of PFOS, PFOSA, PFOSAA, POAA, PFHS, M556 and M570 in Human Serum by LC/MS/MS, Northwest Bioanalytical (NWB), Study No. NWBS00-040, Report No. NWBR00-122, November 20, 2001. 4. Sample Analysis Report for Protocol EPI-0011, Quantitative Determination of PFOS and Related Compounds in Human Serum by LC/MS/MS, Northwest Bioanalytical (NWB), Study No. NWBS00-088, Report No. NWBR01-001, November 30, 2001. 85030000004 iBO ON Niv'XNOO 85030000004 77 5 <2 000001 Page 2 Document Control Office (DCO) 5. Sample Analysis Report for Protocol EPI-0013, Quantitative Determination of PFOS and Related Compounds in Human Serum by LC/MS/MS, Northwest Bioanalytical (NWB), Study No. NWBS00-128, Report No. NWBRO1-066, January 9, 2002. 6. Sample Analysis Report for Protocol EPI-0016, Quantitative Determination of PFOS and Related Compounds in Human Serum by LC/MS/MS, Northwest Bioanalytical (NWB), Study No. NWBS00-145, Report No. NWBROl-155, January 10, 2002. The first three reports listed above refer to the assay validation methods developed by Northwest Bioanalytical. The fourth, fifth and sixth reports listed are the final analytical reports from Northwest Bioanalytical of the children, adult and elderly serum study data, respectively. The statistical analyses of these data have been previously submitted to the EPA by 3M. We will continue to provide information as it becomes available. Please feel free to contact me if you have any questions. Very truly yours, cc: Dr. Charles Auer Dr. Oscar Hernandez Michael A. Santoro Director of Environmental, Health Safety and Regulatory Affairs Specialty Materials 3M Center, Building 236-1B-10 St. Paul, MN 55144 651-733-6374 (phone) 651-733-1958 (fax) E-mail: masantoro@mmm.com 000002