Document 5L3aYG3w1GMJp8DnkyrN5pz3e

TELEPHONE NATIONAL *468 NATIONAL *408 yjuu/ctL 'i-jf-s/s- Manufacturing Chemists' Association OF THE UNITED STATES (FOUNDED 1872) ifupcKNK.X*WM*ATSON 608 Woodwahd Building Washington 5, D. C. MINUTES OF MEETING LABELS AND HSCAUTIONARY INFORMATION COMMITTEE parlors E and H, Hotel New Yorker, Mew York Thursday and Friday, October U and 5* 19h$ D-55 The meeting was called to order by Chairman V/* -N. 'Watson at 10:15 A.M*# recessing at U si+O P.M. on October lu . The meeting on October 5 opened at 9*30 A.M. and adjourned at I*. :U5 P. ii. The following members were present* W. N. Watson, Chairman T* R. Aalto Carl Anderson T. Pat Callahan (Oct.It) A, G. Cranch J. T. Fuess R, F, Hansen S. J. Hill (Oct. 5) D. D. Irish R. .VI. -Lahey Frank S. Low J.A.Noone (Alt*-for L, L. Hedgepeth) Dr. Allan Fleming (Alt. for S.J.Hill) Guests J.; B. Williamson. I. NEW LABELS (Part I covering recommended labels for new products, follows) lr-$6 part i 1. PRODUCT LABELS Recommended Labels for New Products The following labels presented by the respective subcommittees were approved: iACBTALDEHTDE " DAeiUEill Extremely Flammable. Keep aw?iy from heat and open flame* Use with adequate ventilation. Avoid prolonged breathing of vapor. ALLYL ALCOHOL Dangerous because rapidly absorbed through skin. Extremely hazardous vapor. Dc not get in eyes, on skin, or clothing. Do not breathe vapor* Do not'take internally. In case cf contact, immediately flush skin or eyes with plenty of water for at least l minutesj remove and wash clothing before refuse. AKTILOril TRICHLORIDE DANGER! CorrosiveLiquid - Hazardous Vapor. Avoid contact. Avoid breathing vapor. Keep bontainer tightly closed. In case of contact immediately flush skin with plenty of water for at least 15 minutes; remove and wash clothing before re-use. CYCLOHEXANE DANGER] Extremely Flammable. Keep away from heat and open flame. Use with adequate ventilation. Avoid prolonged breathing of vapor. Keep container closed. CYCLOHEXANOL - CYCLOHEXANONE CAUTION! Harmful Vapor. Avoid prolonged breathing of vapor. Avoid prolonged or repeated contact with skin. Use with adequate ventilation. DIOHLOROETHYL ETHER CAUTIONi Volatile Solvent. Use with adequate ventilation. Avoid prolonged breathing of vapor. -DIETHYLENE DIOXIDE WARNING] Flammable. May Cause Skin Irritation. Keep away from heat and open flame. Avoid breathing vapor. ETHYL ACETATE "WARNING! Flammable. Keep away from heat and open flame. Use with adequate ventilation. Avoid prolonged breathing of vapor. ARSENIC TRICHLORIDE DANGER' Corrosive' Liquid - Extremely Hazardous Vapor. Avoid all contact. Avoid breathing, vapor. Keep container tightly closed. In case o.f contact immediately flush skin with plenty of water for at least It* minutes; remove-and wash clothing before re-use. X. POISON .X CADhiiri, CG11RQUKDS vVARUIhCi Harmful Dust. Avoid prolonged breathing of dust. Keep away from feed or food products. Do not take internally. CRESOL Same us rhenol (See Manual L-2) ETHYL BROMIDE WARNING! Harmful Vapor. Use with adequate ventilation. Avoid prolonged breathing of vapor. Keep out of sun and away from heat. ETHYL CHLORIDE DANGER! Extremely Flammable. Keep away from heat, sparks, and open flame. Use with adequate ventilation. ETHYL METHACRYLATE MONOMER WARNING! Flammable. Avoid prolonged breathing of vapor. Avoid contact with skin or clothing. Use with adequate ventilation. iMB CHLORHYDRIN jangerous BecauseRapidly Absorbed Through Skin. ; Extremely hazardous vapor. ,,Do not get on skin or clothing. Do not breathe vapor. Do nc.t take internally. In case of contact immediately wash vdth soap and plenty of water. Poison. If swallowed make patient vomit immediately (finger down threat) c~ give warm r.ustard water or aaiit water freely. General: ueep patient warm; if consoleos give black coffee* Call physic?an. Note: Do not give adrenalin. ETHYLENE GLYCOL kODOBUTYL ETHER Sffi-IYLEire glycol i dNgHtLyl ETHER ETHYLENE GLYCOL AONOETiiYL ACETATE ETHYLENEGLYCOL MC^OhEKi YI, ETHER" CAUTION 1 Volatile Solvent^ lise with adequate ventilation. Avoid prolonged or repeated breath ing of vajjor, or contact with skin. METHYL BUTYL KETONE WARNINGI Flammable. Keep away from beat and open flame. Avoid prolonged breathing of vapor. METHYL CYCLGilSXANOL CAUTIOJvl Harmful Vapor. Avoid prolonged or repeated contact with skin. Avoid prolonged breathing of vapor. Use with adequate ventilation. METHYL CYCLO-TEIaMONS CAUTTGFi Harmful Vapor. Avoid pr.jlonged or repeated contact with skin. Avoid prolonged breathing of vapor. Use with adequate ventilation. METHYL- ISCri-.CrYL IffiTOEE WARNING I Flammable. Keep away from heat ar.d open flame. Use with adequate ventilation. METHYL MET. -.ACRYLATE MONOMER WARMING! Flammable. Avoid prolonged breathing of vapor. Avoid contact with skin or clothing. Use -with adequate ventilation. i; MONONITROPHENOL ^*1 WARNING! May Be Absorbed Through Skin. Avoid breathing dust. Avoid contact with skin. In case of contact immediately wash with soap and plenty of water. PARA TERTIARY BUTYLCATECHOL WARNINGl Causes Skin Irritation. Yi/hen moist causes burns. Do not get in eyes, on skin or clothing. In case of contact immediately wash with soap and plenty of water. PARALDEHYDE CAUTIONi Harmful Vapor. Use with adequate ventilation. Avoid prolonged or repeated breathing of vapor. Do not take internally. Solidifies at about 5UF (12C) and may break container. Store in a moder ately warm place. PROPYL ACETATE WARNING J Flammable. Keep away from heat and open flame. Use with adequate ventilation. STYRENE MONOMER WARNING! Harmful Vapor0 Use with adequate ventilation. Avoid prolonged breathing of vapor. Avoid prolonged or repeated contact 1with skin. SULFUR CHLORIDE (U types) DANGER! Causes Burns. Irritating Vapor. Avoid contact with eyes, skin, or clothing. Drum Handling and Storage Keep Plug Up to prevent leakage. Keep Drum Out of Sun and away from heat. Relieve Internal Pressure when received and at least Weekly thereafter by slowly loosening plug. Retighten immediately. Never Use Pressure to Empty. Keep Lights, Fire and Sparks Away from drum openings. Drum Must Not Be Washed Out or used for other purposes. Replace Plug after withdrawal and return with empty drum. Do not add water to contents while in a container as under this condition the material reacts violently. In Case of Spillage, flush with LARGE VOLUME of water. First Aid In case of contact, immediately flush skin or eyes with plenty of water for at least 15 minutes. sSHIfUR CHLORIDE (continued) *;r Carboy Handling and Storage Before I tovine Carboy be sure closure is securely fastened. Loosen Closure carefully. Keep Out of Sun and away from heat. Never Use Pressure To Empty. Do Hot Add Water to contents while in a container as un-ior this condition the material reacts violently. Completely Drain Carboy Before Returning. In Case of Spillage, flush with LARGE VOLUME of v;ater0 l''irst Aid In Case of Contact, immediately flush skin or eyes with plenty of water for at least I'J minutes. L-58 SULFUR DIOXIDE (uhdor^prd S3uru) WARNING! Extremely Irritating Gas and Liquid. Avoid breathing gas. Do not drop cylinder. Do not allow cylinder temperature to reach 130F. AROMATIC AMINES Recommendations r 1. Labels should be directed to pure products only, and if hazardous impurities .are usually present in the commercial product the manufacturer should add appropriate warnings for such impurities. 2. It was agreed that the cautions used for meta and paranitroaniline could be applied to most aromatic nitroamines. 3. It w'as recommended that aromatic amines other than those for which labels have teen recommended should be considered individually in accordance with known hazards. Those compounds, the hazards of which are not known, should be considered individually from the point of view of the desirability of prescribing some general precautions in their handling such as the sample label in LAfI Manual L-l, Page 7, Schedule !; PARATQLU1DIi-fE ~ WARNING! hazardous Solid and Vapor. Rapidly absorbed through skin. Avoid contact with skin and clothing. Do not breathe vapor. Use witn adequate ventilation. In case of contact immediately wash thoroughly with soap and plenty of waterj rer.ove and wasn clothing before re-use METATOLUIDINE ORTHOTOLUIDINE XILIDINES WARNING! Hazardous Liquid and Vapor. Rapidly absorbed through skin. Avoid contact with skin and clothing. Do not breathe vapor. Use with adequate ventilation. " In case of contact immediately wash thoroughly with soap and plenty of water; remove and -wash clothing before re-use. L-59 ALPHANAPHTi [ZLAI-'Ii IK ' CAUTIOi.'i Hay be Harmful if Repeatedly- Absorbed. Avoid repeated breathing of dust. Avoid repeated shin contact. jVJ?APHS?IYliSKE DLUIEIB cAlii'ICilvi i.iay Cause Skin Irritation. Avoid breat.-ling or contact -with dust* DINITROliOnOIlETi iYLAMILlHK Shipped in aciu solution in tank cars by one manufacturer only. Mo label recommended* 3ETANAPTH0L No label recommended* PARANISIDIKE YEARNINGl Hazardous Solid and Vapor. Absorbed through skin. Avoid skin contact. Avoi.d breathing dust or vapor. PARAPHENETIDE: ORTHOPHEHETTDIN CAUTION! Hazardous Liquid and Vapor* Absorbed tlirough sicin. Avoid skin contact. Avoid breathing vapor* BENZIDINE (including Benzidine Salts &. Base) WARNING! Hazardous Solid and Vapor* Rapidly absorbed through skin. Avoid breathing dust or vapor. Avoid skin contact. MBTANITRQANILINB PARANITROANILIiJE PARANITRO-ORTHOTOLUIDIMS META NITRQPAM-AMIS3DINB WARNINGi Harmful Because Absorbed Through Skin* Avoid skin contact. Avoid breathing dust. In case of contact immediately wash thoroughly with soap and plenty of water3 remove and wash clothing before re-use* QRTHOANISIDIHE WARNING! Hazardous Liquid and Vapor. Absorbed through skin. Avoid skin contact. Avoid bre'athing vapor* PARAlflDOPHENOL No label recommended* L-60 PART II II. LABEL ASSIGNMENTS FROM CALIF. LIST figments of.Dr.. Oranoh. Following a review of labels for the following products* based upon the language recommended to the California lA*C.* they were again referred to Dr. Cranch for a recheclc on uniformity of guage of the respective cautions, with the understanding that Dr. Cranch would report to the full committee not later than October 31s Amyl Acetate Butyl Acetate Butyl Alcohol Secondary Butyl Alcohol Tertiary Butyl Alcohol Methyl Ethyl Ketone Hexanone Ethyl Formate Monochlorobenzene Assignments of Carl Anderson. After review of labels submitted, the following items were returned to Carl Anderson for review and reconciliation with prior recommendations to the California IAC: Ethyl Ether Bichloride of Mercury Silver Nitrate Ethylidene Dichloride. Ethylidene Dichloride was removed from the list of product labels as reports indicated that it is not a commercial item. Fluoride Flux. The report on fluoride flux from L. L. Hedgepeth was continued on the docket. - Antidotes. The following items were referred to the Antidote Committee for recommendation of antidotes: Antimony Trichloride Arsenic Trichloride Ethyl Ether Bichloride of Mercury Silver Nitrate Other Labels. The following products were considered by the LAPI Committee and the Committee concluded, on the basis of present knowledge and experience, that no precautionary information is necessary on labels for these products: Betanapthol Paramidophenol III. OTHER LABEL ASSIGNMENTS Solvents. Dr. Cranch reported that he was not yet prepared to submit his report on solvents. Discussion emphasized the fact that this is the outstanding gap in the LAPI label program and that the chemical industry could not afford to leave this group uncovered. The matter has been pending for one year in the hands of Dr, Cranch1s committee. It was suggested that Dr. Cranch organize subcommittees for different groups and that every effort be made to report to the LAPI Committee-, as these labels should be incorporated in the new Manual L-2 to be printed in December. h ttj<t1f" ` L-61 IfflrfrT Tne` A report from Mr* Remick indicated that the recommendation of the subcommittee is not completed. As this label has been pending since September 19hk it was suggested that the Chairman, with the assistance of one or two producers, review some of the current labels and submit a draft to the Remick committee, stressing the importance of final decision and recommendation 4jbecause of the widespread distribution of this product and contact with the lay |3onsumer. IV. ANALYSIS OF SOLVENTS j|i ----------------------------------- 'll'- The Committee was advised that Industrial Hygiene Information Supplement '-,4/0* 7, Subject, "Solvents Index," dated August 2, 191/5, prepared by the Office Ibf the Chief of Ordnance, Safety and Security Division, 333 North Michigan lj?iAvenue, Chicago 1, Illinois, contained in Table 2 a list of solvents, name of 4-supplier or manufacturer, and the percentage composition according to three ' groups: (l) aromatics, (2) alcohols, esters, ethers, and ketones, and (3) i:paraffins and naphthenes. :* pi-;.' V. MIXTURES * Mr. Hansen submitted a report on Mixtures, which was approved for inclusion jin the next print of Manual L-l. r- VI, REVISION OF ANTIDOTES Mr. Anderson reported on behalf of Dr. Carlisle that the list of antidotes 4br label requirements, appropriate for the lay user, has not been completed. 3;,-This assignment followed a request by Dr* Cox to the LAPI Committee for a revispy|an of antidotes for submittal to the California Pharmacy Board. It was agreed Tiiitihat the matter should be expedited as it has been pending for about a year* Mr. Hansen offered the services of Dr. Knapp of his company to assist in the preparation of these antidotes, and the Chairman was requested to contact Dr. Carlisle on the question* VII. ADHESIVES The Committee approved the report of Chairman Hill, which was sent 'to each member of the Committee on July 23, omitting the last two paragraphs conce'rning new products. This report shows that resin adhesive Q-3605 of the National Starch Products Company, 230 Madison Avenue, New York City, is easily applied for over- and under-treatment and is resistant to water and submersion, as set forth. VIII. M.C.A. LABEL INVENTORIES The Chairman reviewed the label inventories in the Washington Office, amounting to 800,000 for C-5 and C-6 labels. He asked the cooperation of members in using these carboy labels before transferring to the subsequent label recommendations of the LAPI Committee,. IX. SULFURIC ACID IN DRUMS LABEL The Chairman reported that the sample label for sulfuric acid in drums had been submitted to the LAPI Committee on July 19 with a price of &1.90 per 1,000 (minimum order, 10,000), plus 35(4 per thousand, in large lots, for name imprinting. Ho stated that Committee members had indicated no present interest in securing this label, . L-62 X. COLOR CODE The Chairman was requested to make strike-offs for Committee use only, using the model acid label, showing red, blue, green and yellow in accordance with hr, Lahey's subcommittee report dated February 26, 19U3. XI, DEFINITION OF CORROSIVE LIQUIDS The Chairman advised the Committee that the majority recommendation of the members favored the revision of the definition for "acids and other corrosive liquids" (paragraph 21^0 of the I'.C.C. regulations), suggested by the Bureau of Explosives and referred to the LAPI Committee on July 30. He stated that the 3ureau had been notified of approval of the suggested revision as a distinct improvement over the existing definition. XII. RHODE ISLAND CODE The Chairman reported that i-ir. H, F, Reinhard had appeared before a special commission of the R. I. Department of Health on September 18, representing the LI.C.A. in connection with a proposed code for the manufacture, use and storage of industrial organic solvents in places of employment, which contained a refer ence to the incorporation of LAPI Manual L-2 labels and supplements thereto. The K.C.A. position on this code, with particular reference to the inclusion of Manual L-2 was outlined in the association's General Bulletin of October 2, 19U> and a copy of the statement presented to the Commission by Dr. Reinhard has been sent to members of the LAPI Committee. XIII. JOINT DDT COMMITTEE The committee reviewed and approved the recommended cautions prepared by the Joint Committee, consisting of two members each from the AIFA, NAIDM and the ifi. iiCA, with Dr. Paul A, Heal of the TJ.S. Public Health Service, and the late ; > Dr. H, 0. Calvery, Division of Pharmacology, Food and Drug Administration. XIV. REVISIONS OF CALIF. I.A.C. PROPOSAL FOR LABELING OF INJURIOUS p::; .. Mr. Hansen reviewed in detail the appearance of Dr. Harold E. Wales on behalf l||;bf the M.C.A. at the hearing before the California Industrial Accident Commission on October 9* The pre-hearing draft of the I.A.C. regulations was sent to the entire M.C.A. membership in August, and a copy of our recommended revisions was sent to each member of the LAPI Committee on August 27, special attention being y:-; given to the provisions of Orders 9U.1 "Application'.' $ 9U*2 "Definitions" j 9lu3 p; ; "Labeling"; 9kh "Caution Phrases", in connection with which we recommended incorporation of Schedule 3 of LAPI Manual L~l; and 9h5 "Labels", in which recommendations for revision of specific cautions were presented. XV. GENERAL SAFETY COMMITTEE The Chairman reported that the General Safety Committee had drafted chemical safety data sheets on twelve products and that redrafts had been prepared on six items which, after approval by the General Safety Committee, mil be submitted to the concerned M.C.A. Committees for comment. These include the Container Committees, Medical and Legal Advisory Committees, and the LAPI Committee. h L-63 XVI. MISCELLANEOUS Caution Labels for Insecticides and Fungicides. The subject of preparation of caution labels for insecticides and fungicides was discussed in detail and the Chairman was requested to appoint a subcommittee to initiate this project. The subcommittee follows: Richard Hansen, Chairman L. L. Hedgepeth S. J. Hill D. D. Irish DDT. Mr. Hill reviewed his recent visit to eight states with Mr. Hedgepeth, in the course of which concerned officials were interviewed concerning appropriate labels for DDT formulations, with emphasis on the important part that Manual L-l played in the concept. He recommended that a representative be sent to the meeting of North Central States officials in Omaha, Nebr. on October 16-17, The committee approved this recommendation for submittal to the Executive Committee. Dr. Irish agreed to take up the question of a label for DDT formulations with officials of the State of Michigan, Manual L-l. Each member of the Committee agreed to submit to Chairman Lahey before December 1 comments and recommended revisions for Manual L-l, for inclusion in the next print which will contain the approved report on mixtures submitted by Mr. Hansen. Manual L-2. Mr., J. T, Fuess was appointed Chairman of a subcommittee to revise Manual L-2, including all labels cleared by the LAPI Committee since its publication, and to include the solvent labels following approval. It was agreed that (l) the revised L-2 should be in the hands of the committee well in advance of the next meeting of the LAPI Committee on December 6 and 7 and (2) comments of committee members on the revision should be submitted to Mr. Fuess before November 1. Chlorine Mr. Frank Low reviewed the draft of a chlorine label prepared by a subcommittee of the Chlorine Institute. Comments and suggestions were made to Mr, Low for his information. Next Meeting. It was decided that the next meeting of the LAPI Committee should be held in New York City on Thursday and Friday, December 6 and 7, XVII. ADJOURNMENT There being no further business, the meeting adjourned. W. N. WATSON Chairman Minutes subject to approval