Document 4QVYELa72YxkxxNZbLd5NR8ze

3M Corporate Toxicology and Regulatory Services 3M Center, Building 0220-06-E-03 ` St. Paul, MN 55144-1000 651 733 1773 Fax P-1 Certified Mail y ry ?I yr.*. , iI y7 I " 1 fv.-:* !1 rw> tf January 8, 2007 NO CBI Document Processing Center EPA East - Room 6428 Attn: Section 8(e) Office of Pollution Prevention and Toxics US EPA 1200 Pennsylvania Avenue NW Washington DC 20460-0001 RE: TSCA 8(E) SUBSTANTIAL RISK NOTICE ON: PFHS and PFOS; Supplemental to Sulfonate-based Fluorochemicals, Docket Nos. 8EHQ-1180-374; 8EHQ-0381-0394; 8EHQ0598-373 Dear Sir/Madam: In July of 2006 3M notified the EPA that preliminary data had been received from a study suggesting an effect of perfluorooctanesulfonate (PFOS) and perfluorohexanesulfonate (PFHS) on body weight, food consumption, and serum cholesterol in 15% dietary fat fed E3 Leiden transgenic mice in vivo. The final report for this study is enclosed. If there are questions, or if additional information is needed, please contact me at (651-737 1374). Sincerely, t X Deanna J. Luebker, MS, PhD 3M TSCA 8(e) Coordinator Enclosure CONTAINS NO CBI j' 89070000087 e 9u 00 U 'V.- 08