Document 3QjEb7nGbRZODrJ7wVwNKnX0O

D.W.H. CUSEY Bth October, 1970. P.C.B'a. omc/m .r. RECAN. vs Q> StU I A meeting concerning polychlorblphenyla in eamaetlon alth CLC analytical methodo and t'lldllfa aaa held at tha Tuntall Laboratorlaa of Shell fleeeareh limited at Blttlnnboume, Kant an 30th Boptambat 1970. Tho neolinq aaa errenoad by tha Piniatry af Agriculture, fleherlaa and rood, and folloeed a alnlla* aaatlna hald in 1949. Approximately fatty paoole attended, aalnly from varloua branched ef tha rinlatty and ralatad naaaareh Aeaoelatlane. reurrel Unlvaraltlaa aata repreaented. Induatrlal tapranantatlan aaa llnltad to 'jnllover, Shall and I'.onaanto. Tha proeeadinge aara conducted infernally, although oreeentntlane on vnrloua teplea ma aada In btlaf laetura fora# Sona notaa ara prevented. gevo a btlaf account of tho ptavlaua moating ahleh had baan hald to dlaeuaa vatloua eapaeta <f PCS determination. Tha intaraat had atlaan fron aotk carried out on determination of varloua chlorinated peeteldo realduaa in animal and nqtleultural aanplaa ahota tha PCS'a flrat appeared aa untmoan contaminating paaka. A. Wlohardaan fthalll dlaeueaod cone eapaeta of DOT and PCS analyila, Ha aantlonod durq | Canada] mho had evolved a technique af catalytic ' raductlon/hydroqanatlan converting PCS'a to dleyclohaayl typo hydrocarbana fat flD datermination. Thia aaa generally thouqht to be ef little uaa if tha analyet had aaeeaa te CC detection. Cleanup tachnlquaa aara briefly mentioned. Tailing A Sleaena funllavorl outlined their aathode amphaelrlng an ottldatlvo elaon-tt) procedure. Total reeovorlaa aara good. In the MMl! range alth tha main loaaaa occurring during aclvant removal. Thait main raaaarohmtypa development aaa a ohift to high.revolution [eg. capillary^ chromatography alth uee of cowled phyolcal cathode a.g. WW or tes In order to oatabllah peek Identity. Thla ahoaad that com ordinary CC paaka aara actually aultlplata. m Clocking up proeadurea aara mentioned, etroeelnq their need ahare other realdue paaka overlay PCS oaake. A nee r.c otatlonary phaee polypephanopylona had bean triad and aoc ana of tha fee phaaoa found to eluta DDC [a chlorinated PfuUelrio] In an area free from largo PCS paaka. Thm pheeo had a good wper tomparatuca Unit of about aork. Prom The Desk OP W. B. Papageorge 11 -70 /coni. MONS 099957 z o ** briefly outlined the net position oo for a* onolytleal methods am concerned Mentioning thet the MC "methodology package" had been node available. The present ceeenteh Investigations Into hlgtwreaolutlan GC olth otho* phyuleel eethode being used to eatabllah peak Identity ooro else Indicated* The writer, aeked to eoenont briefly rron a ylait producing Aroclors, eutllned the equipnont evallobla at Neeport and Mentioned our Monitoring of effluent dtceherge and edvlaary carvlee to customers, or any other Interested parties. Profreeeor van Cenderen [Utrecht, Holland! described eons of the cork on PCO'e at Ulrseht. Three ooonarelal chlorinated dlphenyla ooro being looked at In one portleuler Investigation. These ooro, Aroelor 1ZG0, Clophen [of Cernan erlglnT teyorj end Pheneehlor [freneh origin - T Prodelee*), both of the letter being In the eane range as 1260. these three appeared ta be of different toaieity levole olth Iroelor 1280 being the leest heroful fro the etudles olth controlled diet feeding to rate. Analytical Investigation shooed that the Clophen and Phenechlor contained coapoistde of the following typesi CL U. tetra ehler dlbenrefuren [ponte] Tatra ehlor dlbenro dtoxadlene [pants] oMeh free ether eerk ere kneen to be quite taxlei In particular they eon set 19. akin eontUtlone of the ohlot-ocne typo, monsurnwent and Identlfleatien oero aade by a eeeblnetlon ef gee ehroaeteqrsphy end ness epeetrenetry. Arcelor 1260 see found to have none ef these eeepeiwde. Clephen could have tp to 5 ppn and Phenechlor up to 20 ppn. Helden ffishery Beeooroh, Pitlochry], apoks about poselble nodes of entry of PCB'e into the third environment [ospoclally the narlne environment]. One apporont source that they had uneovered aes froa the dueplng ef sewage sludges. Sewage feme in the deepen area periodically dugwd elbdgea aell dean the Clyde and sesu, but not ell or theao feme hod eludgee olth PCR eontente giving a total dunp of about 1 ten of PCB per year. Slnller checks in the tendon area hod shown the*sene state ef affaire. The Bristol region, however, had not shown any worthwhile dmp rets. The epeeksr eondered whether lend dingo else presented s poselble route vie the anInal feeding chain i.e. for snail ersaturse to pick m Pen's in their diet, ending i porhsee with the large animals such as blrde and various marine enlaals. He nonUnhid that es yet no PCB'e had been fowd in fresh eater flah /eant. HONS 099958 franklin Tf.holana Collnnol. Speaking an onryme induction offnot* of PCS'* _ clnnerlbod (pertinent* in prograoe on rots where rsthor lorgo [29mc/kq bodyweight] V Injoetlan* of Atoolor 1242 wro given. In teat* looting up to 20 day* no 111- offoeto ton oboerved In that tho rote did not rilo and remained vlolbly healthy, pn examination choobd the exacted lneroooo In fatty tlaouo mound tha llvor Meh la not paoullat to PCS'*, but la eauood by many ether eompounda aa eell. Varloua In vivo and In vitro taoto aara daoerlbad to domonotrata that the PCS ffaet earned to ba eaualng an Ineraaaed production of varloua anrynaa. fimmal mediation. . Conaldarabla gonaral dloeuaolon took place and aoaa polnte are noted balooi 1* Tho Ponoanto attitude to the PCn ouaatlon aao aarmly aaleomed In that the Company ano taking pert In the proKent dloeueelone. In that It made Information on methoda roudlly iv-llablo and provided aamploa of Areclora, and aaa plainly eem to bo co-operative* I* Deny opeekara dapracetad the Praoa praoantatlon on PCS'* which tended to laply that thla aaa the mejor raaaon for toalo nffeota partleularly on aaa blrda and other earlna aniaale* Ae one apaaki.r aucclntly put It *ohy blame PCO'eT*. It aaa hoped that the praoant accent on PCS'* aaa not drawing off lameeeaaerlly a large anoint of technical effort. Here the PCI people could only point out that aroelora had boon made in thla cointry for 2 yeara* and In the U.S. for obout 20 yeare before that and that one night have apaaotad toxio offaeta to have ahoan up earlier* 3. Tpa Btlatol Channel aran aaa mentioned aa having boon aurvoyod for evldanee of PCS'a and eome eurpriee aaa fait at vlrtaally none being found, although the Hoepart Plant aaa In that area. We atreeead that our eorka affluent awe non1torad and tho PCB dieeharge aaa at o very loa figure, [no figure uea nontlanad, nor aaa refarenew made te aatuarina mud axaminotlon], 4. One npoekar guaottuned the normal variation In chlorine content of on Drooler. The anoner of about r 0*6< an the nominal value atth no effect on the intarorotation of a PCS chromatograph aaa oetlafactory* Thla queetlon aaaaod to lndloata that many people marking In thla field did not have oil tho technical information available to than. The lnoraealon aaa formod that aoma paeplo althout a chemical background fait that a.g. Aroelor 1242 non a dlotlnet chemical entity, different from o.g. Drooler 1254, and did not fully appreciate that both aero mixture* of aimllar ehloro eompounda In differing ration. 5. harttion aaa made of the fact that anna toxicity aork aoo being dona on Aroelor 12S0, eome on 1242 end eo on. Thie led to gueetlone on the quentltlno produced of the varloua grade* and alaa on the uaa-pattern by area and parhep* by lnduatry. Doha of thnaa oimatlona nee ancoarad directly, but It aoo pointed out that eertein Information might ba made available to aorkere In the field If e written reguoat aaa praaantad. ' . MONS 099959 /cent... f 0 -4 - ThIs might enable Interoet to ba aoneantrated an aona PCB'a aora oldoly ucod than other*. It *oa further pslntnd out that PC aaa not tha only producor af PCB'a and thua North Boa pollution alqht ba arlalnq not fro* DC notarial. In thla raapaet aona of Profaaaer van Condaron'e ranorho oaro quit* relaxant. (. Tha trend to high-rooolutlon CC and lndontlflootton of paaka prontad aavaral people to point out that than oould bo eonaldaroblo dlffaranenm in taxlolty batooon tha varloua ooaponanta of a PCD. Although tha claa of the teak of Identifying all tho pooka in a chromatogram oeo large enough, that of attempting tonicity atudlaa on Individual coapenenta aaa vary nuoh larger. The moating aarvad to keep Heoport in touch dth poaalbla analytical ' ' davalapmanta In tho PCI riold. and alao outlined tha alder coaplleatlonc. It aaa alao fairly abvloua that although tha Company ho* made nueh Information avallabla. *e might etlll have more to do In tha aduaatlva line oven If only to anauro that people do not aaka ortanaouo aaauoptlona about PCB'a. . /f\/^ WtMuOSU MQNS 099960