Document 0q3Z3YGJQ0rJkabpnadgkBDLm

800 North Lindbergh Blvd. , St, lewis 66 Mlssot CHEMICAL SPECIALTIES DATA REPORT The information in this r>t>orl was compiled to assist you in your evaluation and development of special uses for Monsanto products. Kvery effort has been made to include pertinent material beorinft on the subject. Thin information is intended No. C (j ffJo7E. ' lvc+e_ Date Marcb, 1961^ to Ruido your development work, but Monsanto cannot take part in the specific formulation or evaluation of any finished product. . . since knowledRe of auch should be reserved to youraelt and ia often your most valuable trade secret rytdT yfc ^ik'UcU- ~7%^> f/CevsW MONSANTO AROCLOR* RESINS FOR INSECTICIDE FORMULATION:'. A Discovery ||a simple method of increasing the service life of expensive II lindane sprays was developed several years ago by U. 3. Depart- I II ment of Agriculture scientists at their Beltsvll.le, Maryland, I testing station. The technique was to incorporate Monsanto's "Aroclor" 5^60, a resinous chlorinated terphenyl in the lindane solution. This pale yellow solid reduces volatility of the i lindane -- slows it down to an effective, but not wasteful, I evaporation rate. The result is an insecticide deposit on treated surfaces that lastB up to ten times longer than that left by straight lindane solutions. Normally, simple solutions of lindane leave a crystalline residue that dissipates within a few weeks. On hard surfaces such as glass, metal or painted areas, the residues last only about a week. Because lindane is a well established and effec tive pesticide, U.S.D.A. researchers sought a way to improve the lasting qualities of lindane residues, of numerous com pounds tested, "Aroclor" 5^60 gave the best results at lowest cost. Test Work A major objective of these studies was to develop a suitable formulation for application to crops and other plants. Al though results under carefully controlled conditions were quite promising, subsequent tests by other agricultural ex perimenters gave only moderate success. Consequently, interest has been slow to develop in agricultural circles. Apparently, the vagaries of sunlight, weather, and plant growth represent too many variables for effective study of the formu lation residues by direct application to exposed plants. * Aroclor: Reg. U. 3. Pat. Off. i 021^2 \ Tha Information In ihla buU.tln la, to our baM Imowladfa, troa and connwtkm with tha u*n of ibwt data r unfaallona aocurnla, but all wcommondatlona or mj**atlon< ar mada without Furtbarmora, nothin* eontnlnad harab> xhall ha cnnalruad aa a raoom ffuaranlao, .Inca tha condition* of uaa nr* bayonet our eonlro). Tha mandatlon to uaa any product in conflict with aatattn* pa tan t* covarin* I Motwanlo Chamloal Cpmpany dlaolalma ary liability ipeurrad In r 'Mv.vl/- ` -<.' r Pti 't ' ' * * 1 Any malarial or It* uat. EX P-2891 ad 7 Page 1 of 6 PCB-ARCH0748937 <;) ) A New Idea But another possibility for putting the U.S.D.A. discovery to work has lain dormant until recently; thia is the poBBlblllty of using to good advantage the ability of "Aroclor" resins to make the lindane adhere to smooth hard surfaces like metal, glass, painted areas, eto. This would oonslst of painting or spraying "Aroclor"/llndane formulations on such areas as the Inside of garbage can lids, on window screens, doorsllls, the painted walls of outbuildings, dairy plants, storage areas, etc.. In order to obtain lasting control of flies, ants, roaohee, sllverfish and other troublesome peatB. Suitable formulations oan be readily packaged in shoe-polish type "dauber" bottles, aeroBol spray cans, and bulk packages for meohanlcal spray application. Development of this Idea is based on the following! Advantages of Using "Aroclor" Resins In Insecticide Formulations * A suitable "Aroclor" (Monsanto makes seven) can remarkably extend the effective life of lindane and othor chlorinated inBeotioldes as much as ten timet, (up to 2 and 3 months). * "Aroclor" resins are very low In cost (around 20^/lb.). * Small quantities are sufficient (5 to 25 parts per hundred, by weight). * Formulation is extremely simple -- the resin is dissolved in a suitable solvent compatible with the insecticide. * Stable In Inventory and in insecticide formulation. "Aroclor" resins are fire-resistant, non-oxidizable, non-coj\roslve, withstand weather extremely well. * Non-Btainlng "Aroolor"/insectlcide films formed when the solutions dry are practically Invisible. "Aroclor" >460 , has a pale yellow color as supplied. Other suitable "Aroolor" products are nearly colorless. * "Aroclor" resins are odorless -- won't Impart "ohemioal" odors. * "Aroclor" resins are safe to handle aB long as they are not volatilized and inhaled. They are praotically non-volatile at ordinary temperatures, do not irritate or sensitize normal skin. * The nature of the residue can be varied. Monsanto supplies a variety of "Aroclor" resins. These are ohlorinated to various degrees and vary in physioal properties as follows* Monsanto Chemical Specialties Data Report CS-6, ....page 2 EX P-2891 Page 2 of 6 PCB-ARCH0748938 o ) Chlorinated Terphenyls Aroclor 5460 - Yellow, transparent, friable solid (dries hard) Aroolor 5442 - Yellow, transparent, sticky semi-solid (dries tacky Aroclor 4465 - Yellow, transparent, brittle resin (dries sticky) Chlorinated Biphenyls Aroclor 1262 - Light yellow, sticky, vIbcotjo semi-solid (dries stii Aroclor 1260 - Pale yellow, soft, sticky semi-solid (dries sticky) Aroclor 1254 - Pale yellow, viscous oil (dries "wet") Experlmental Work and Formulations The following information was derived from preliminary reports on work done by U.S.D.A. research groups. These data are not to be construed as recommendations by either the U.S.D.A. or Monsanto, but rather are intended to serve as a guide or starting point for the development of private formulations. Pifty to 200 milligrams of lindane per square foot of surface haB given good insect control on nonporous surfaces. The ratio of lindane to "Aroclor" 5460 haB been varied from 1:1 to It4. For most purposes a 1:1 or a 1:2 mixture Is satisfactory. Formulations sb used in the U.S.D.A. experiments arei 1) For application as a solution. Lindane "Aroclor" 5460 Carbon Tetrachloride 5 parts by weight 5 parts by weight 750 parts by weight (Carbon tetrachloride 1b toxic and should be handled with extreme caution. Less toxic solvents are easily obtained.) 2) For application as an emulsion. , Lindane "Aroclor" 5460 Yvl ftfifa "Triton" X-100 (available from Rohm & Haas) 20 parts by weight 20 parts by weight 100 parts by weight 3 parts by weight To obtain a stable Vf> lindane emulBlon, mix 1 part by weight of the above concentrate to 13 parts by weight of water. Monsanto Chemical Specialties Data Report CS-6, ..........Page 3 0717522 XX P-2891 Page 3 of 6 I PCB-ARCH0748939 () 3) For uog ao a pressurized (aerosol type),,epray a) Lindane "Arcelor" 5460 Methylene chloride "Freon" 12 (DuPont) 5 partn by weight 5 par to by weight 40 parts by weight 50 parts by weight b) Lindane "Aroclor" 5**60 Cyclohexanone Ortho-dichlorobenzene "Freon" 12 (DuPorit) 5 parto by weight 5 parts by weight 10 parts by weight parts by weight parto by weight Experimental Results - American Roaches Using Formula 3a or 3b, the toxloant was applied onto a painted wall, depositing about 200 mg./sq. ft. of lindane and a like amount of "Aroclor" 5**60. When the toxicant coat was one month old, it gave 90-100^ kill of Amerioan roaches when the roacher contained in a petri dish were placed againBt the surface of the treated Wall for two hours. The U.S.D.A. research team found that the lindane-"Aroclor" 5460 mixture (used at the rate of 50 mg. of actual lindane per sq. ft.) would kill 80$6 of all cockroaches exposed for 2 hours to a 60-dayold treated surface. It remained lethal to 66of the roaoheB after 90 days. Regular lindane sprays used at the same rate killed only 4# of the roaches after 60 days. Results with Houseflies Deposits of 25 mg. of lindane plus 25 mg. of "Aroclor" 5460 applied from carbon tetrachloride onto glass and aluminum (hard surfaces) gave lOOjlS kill of normal houseflies exposed for 2 hours to these treated surfaces after they bad aged 10 weeks, the duration of the test. Without the "Aroclor" the hard surfaces treated with lindane alone were effective only about a week. A lindane plus "Aroclor" mixture sprayed as an aerosol onto leaves of a willow tree continued to kill houseflies after 2 months of outdoor weathering. Careful Inspection of the treated leaves showed that the toxloant was held firmly to the surface and notwithstanding rain and weather, the costing re1 malned in good condition. Also, within limits of a preliminary inspection there seemed to be no ln,1ury to the willow leaves* Monsanto Chemical Specialties Data Report CS-6, ..........Page 4 EX P-2891 Page 4 of 6 PCB-ARCH0748940 ) (Notes The primary purpose of thin report io to provide in formation for the development, of suitable insecticide formula tions for application to "nonnonsltive" surfaces such as metalB, glass, paints, and other materials that will not be damaged by the application. Development of formulations for living plants requires sufficient test work to Insure that the formulations will not be injurious to the plants or their products.) Anothor Formulatlon Report ed A more recent development In these experiments is the following simple formulation: "Aroclor" 5**60 25% Lindane 2$% Methylethyl Ketone (MEK) 50/> Work on this was reported in the August l'l, 195*1 issue of Chemical Week magazine. This simple formulation appears to be most suitable for "painted on" formulations packaged in bottles but should be used with caution in mechanical spray equipment since the MEK solvent will soften rubber and certain plasties. The formulation could also be modified easily for aerosol packaging. Since MEK evaporates rapidly, it should not seriously affect painted areas unless too heavy applications are made. The package label should include a caution to this effect. AIbo, MEK is flammable. Possible substitutes that are less flammable are mothylch.1 oroform or a mixture of mothylehloroform and methylene chloride. Formulating Other Insecticides The beneficial effects of "Aroclor" 5**60 apply generally to other chlorinated insecticides including chlordane, aldrin and dieldrin, but do not apply to phosphate type insecticides such as TEPP, parathion, methylparathion, malathion and chlorothion. ' . * * For samples of the "Aroclor" products mentioned In this report, contact the nearest branch office (see attached list) or write tot MONSANTO CHEMICAL COMPANY Organic Chemicals Division PlasticlzerB Department 800 North Lindbergh Boulevard St. Louis 66, Missouri Monsanto Chemical Specialties Data Report CS-6, ....page 5 tip!?* PCB-ARCH0748941 t ) MONSANTO CHEMICAL COMPANY Organic Chemloals Division District Sales Offices ATLANTA: 1*101 Peachtree St. N.E., Atlanta 5, Georgia BOSTON: Everett Station, Boston 49, Massachusetts CHICAGO: McGraw-Hill Building, 520 N. Michigan Ave., Chioago 31, 111. CINCINNATI: 2330 Victory Parkway, Cincinnati 6, Ohio CLEVELAND: 427 Hanna Building, Cleveland 15# Ohio DETROIT: 18230 Orand River Avenue, Detroit 23, Michigan HOUSTON: 2472 Bolsover St., P. 0. Box 6863, Houston, TexaB LOS ANGELES: 6670 E. Flotilla St., Los AngeleB 22, California ! MINNEAPOLIS: Foshay Tower, Room 515, Minneapolis 2, Minnesota NEW YORK: 445 Park Avenue, New York 22, New York PITTSBURGH: 20 Cedar Boulevard, Pittsburgh 28, Pennsylvania SAN FRANCISCO: 111 Sutter Street, San Franoisoo 4, California SEATTLE: 9H Western Avenue, Seattle 4, Washington SYRACUSE: 731 James Street, Syracuse 3, New York WILMINGTON: 2005 Conoord Pike, Fairfax, Wilmington 3, Delaware # # * # LONDON: Monsanto Houbo, 10-18 Victoria St., London S.W. 1, England MELBOURNE: 256 Flinders Street, Adelaide, Australia MONTREAL: P. 0. Box 900, Montreal 3, Canada TORONTO 183 Front St. East, Toronto 2, Ont., Canada VANCOUVER: 1550 Rand Avenue, Vanoouver 14, B. C., Canada EX P-2891 Page 6 of 6 PCB-ARCH0748942